Results 81 to 90 of about 223,316 (222)

Integrative metagenomic analysis reveals distinct gut microbial signatures related to obesity

open access: yesBMC Microbiology
Obesity is a metabolic disorder closely associated with profound alterations in gut microbial composition. However, the dynamics of species composition and functional changes in the gut microbiome in obesity remain to be comprehensively investigated.
Xinliang Hu   +9 more
doaj   +1 more source

Multivariate Analysis of Gut Microbiota Composition and Prevalence of Gastric Cancer [PDF]

open access: yesarXiv
The global surge in the cases of gastric cancer has prompted an investigation into the potential of gut microbiota as a predictive marker for the disease. The alterations in gut diversity are suspected to be associated with an elevated risk of gastric cancer.
arxiv  

Gut Microbiota and Obesity

open access: yesJournal of Clinical Gastroenterology, 2016
Intestinal microbiota is composed by symbiotic innocuous bacteria and potential pathogens also called pathobionts. The human gut normally hosts roughly 1014 bacterial organisms of up to 1000 different species. The genome size of this microbial organ, collectively named microbiome, exceeds the size of the human nuclear genome by 2 orders of magnitude.
VALSECCHI, CHIARA   +2 more
openaire   +5 more sources

From metagenomic data to personalized computational microbiotas: Predicting dietary supplements for Crohn's disease [PDF]

open access: yesarXiv, 2017
Crohn's disease (CD) is associated with an ecological imbalance of the intestinal microbiota, consisting of hundreds of species. The underlying complexity as well as individual differences between patients contributes to the difficulty to define a standardized treatment.
arxiv  

Improvement of Asia-Pacific colorectal screening score and evaluation of its use combined with fecal immunochemical test

open access: yesBMC Gastroenterology, 2019
Background The Asia-Pacific Colorectal Screening (APCS) score is effective to screen high-risk groups of advanced colorectal neoplasia (ACN) patients but needs revising and can be combined with the fecal immunochemical test (FIT).
Xu-xia He   +14 more
doaj   +1 more source

The same but different: impact of animal facility sanitary status on a transgenic mouse model of Alzheimer's disease [PDF]

open access: yesarXiv
The gut-brain axis has emerged as a key player in the regulation of brain function and cognitive health. Gut microbiota dysbiosis has been observed in preclinical models of Alzheimer's disease and patients. Manipulating the composition of the gut microbiota enhances or delays neuropathology and cognitive deficits in mouse models.
arxiv  

Combing fecal microbial community data to identify consistent obesity-specific microbial signatures and shared metabolic pathways

open access: yesiScience, 2023
Summary: Obesity is associated with altered gut microbiome composition but data across different populations remain inconsistent. We meta-analyzed publicly available 16S-rRNA sequence datasets from 18 different studies and identified differentially ...
Yu Lin   +7 more
doaj  

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