Results 71 to 80 of about 1,608 (126)

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

The Effect of Disease and Season to Hepatopancreas and Intestinal Mycobiota of Litopenaeus vannamei

Frontiers in Microbiology, 2019
Increasing evidence has manifested that the gut bacterial microbiota of shrimps is closely related to the environmental factors, host developmental stage and health status like that of humans and animals does.
Juan Li, Haiying Jiang, Linmiao Li, Xiujuan Zhang, Jinping Chen   +4 more
doaj   +1 more source

Microbial metabolites in tumor epigenetic regulation

iMeta, Volume 5, Issue 1, February 2026.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

Exploring the mycobiota in multiple sclerosis: its influence on disease development and progression

Frontiers in Immunology
BackgroundMultiple sclerosis (MS) is a complex immune-mediated disorder influenced by genetic, environmental, and microbial factors. Recent research has focused on the gut microbiota’s role in MS, yet limited studies have examined the fungal microbiota ...
Ane Otaegui-Chivite, Ane Otaegui-Chivite, Miriam Gorostidi-Aicua, Miriam Gorostidi-Aicua, Laura Martins-Almeida, Laura Martins-Almeida, Ainhoa Alberro, Ainhoa Alberro, Leire Romarate, Idoia Mendiburu, Idoia Mendiburu, Amaya Álvarez de Arcaya, Maialen Arruti, Maialen Arruti, Tamara Castillo-Triviño, Tamara Castillo-Triviño, Tamara Castillo-Triviño, David Otaegui, David Otaegui, Laura Moles, Laura Moles   +20 more
doaj   +1 more source

LC3-Associated Phagocytosis Is Required for Dendritic Cell Inflammatory Cytokine Response to Gut Commensal Yeast Saccharomyces cerevisiae

Frontiers in Immunology, 2017
The human fungal microbiota known as mycobiota is increasingly recognized as a critical factor in human gut health and disease. Non-pathogenic commensal yeasts such as Saccharomyces cerevisiae promote homeostasis in the gut, whereas dysbiosis of the gut ...
Dimitra Lamprinaki, Gemma Beasy, Aleksandra Zhekova, Alexandra Wittmann, Steve James, Jo Dicks, Yoichiro Iwakura, Shinobu Saijo, Xiaomin Wang, Chung-Wai Chow, Ian Roberts, Tamas Korcsmaros, Tamas Korcsmaros, Tamas Korcsmaros, Ulrike Mayer, Thomas Wileman, Thomas Wileman, Norihito Kawasaki   +17 more
doaj   +1 more source

Impact of a GABA‐Producing Lactococcus lactis on Microbiota and Mycobiota During CNS Inflammatory Demyelination

FASEB BioAdvances, Volume 8, Issue 1, January 2026.
GABA‐producing Lactococcus lactis protects against experimental autoimmune encephalomyelitis (EAE) in a mouse source‐dependent manner. The study focuses on the therapeutic potential of genetically engineered gamma‐aminobutyric acid (GABA)‐overproducing Lactococcus lactis (P8s‐GAD L. lactis) in the EAE model.
Kristina Hill, Alexandra LaFollette, Trevor O. Kirby, Soledad Negrete, Dani Babcock, Kari Felton, Hannah Kohl, Kavita Sharma, Andrea Castillo, Jean‐Baptiste Roullet, K. Michael Gibson, Javier Ochoa‐Repáraz   +11 more
wiley   +1 more source

Advancing Yeast Identification Using High‐Throughput DNA Barcode Data From a Curated Culture Collection

Molecular Ecology Resources, Volume 26, Issue 1, January 2026.
ABSTRACT Yeast identification is essential in fields ranging from microbiology and biotechnology to food science and medicine. While DNA barcoding has become the standard for identifying cultured strains, environmental DNA (eDNA) metabarcoding has revolutionised microbial community profiling, providing deeper insights into yeast communities across ...
Duong Vu, Michel de Vries, Bert Gerrits van den Ende, Jos Houbraken, R. Henrik Nilsson, Balázs Brankovics, Margarita Hernández‐Restrepo, Johannes Z. Groenewald, Pedro W. Crous, Ferry Hagen, Wieland Meyer, Gerard J. M. Verkley, Marizeth Groenewald   +12 more
wiley   +1 more source

The interplay between tissue‐resident microbiome and host proteins by integrated multi‐omics during progression of colorectal adenoma to carcinoma

iMeta, Volume 4, Issue 6, December 2025.
This study integrated metagenomic and proteomic profiling of 185 colorectal tissue samples—spanning adenoma (A), tumor (T), and para‐tumor (P)—to characterize multi‐kingdom microbiome and host protein dynamics in colorectal cancer (CRC). In total, 4057 bacterial, 61 fungal, 108 archaeal, and 374 viral species were identified, revealing CRC‐specific ...
Di Wu, An‐Jun Wang, De‐Chao Bu, Yan‐Yan Sun, Chen‐Hao Li, Yue‐Mei Hong, Shan Zhang, Shi‐Yang Chen, Jin‐An Zhou, Tian‐Yi Zhang, Min‐Hao Yu, Yong‐Jing Ma, Xiu‐Li Wang, Jia Xu, Wei He, Christopher Heeschen, Jian‐Feng Chen, Wen‐Jun Mao, Hui Ding, Wen‐Juan Wu, Yi Zhao, Hui Wang, Ning‐Ning Liu   +22 more
wiley   +1 more source

Interaction between intestinal mycobiota and microbiota shapes lung inflammation

iMeta
Gut microbiota is an intricate microbial community containing bacteria, fungi, viruses, archaea, and protozoa, and each of them contributes to diverse aspects of host health.
Youxia Wang, Fang He, Bingnan Liu, Xiaoyan Wu, Ziyi Han, Xuefei Wang, Yuexia Liao, Jielin Duan, Wenkai Ren   +8 more
doaj   +1 more source

Bimodal distribution of intestinal Candida in children with autism and its potential link with worse ASD symptoms

Gut Microbes Reports
The gastrointestinal (GI) tract harbors a complex and remarkably diverse microbial ecosystem that profoundly impacts various aspects of health and pathophysiology.
Khemlal Nirmalkar, Jigar Patel, Dae-Wook Kang, Andrew Bellinghiere, Devin A. Bowes, Fatir Qureshi, James B. Adams, Rosa Krajmalnik-Brown   +7 more
doaj   +1 more source