Despite their crucial importance for human health, there is still relatively limited knowledge on how the gut resistome changes or responds to antibiotic treatment across ages, especially in the latter case.
Xuanji Li +9 more
doaj +1 more source
In recent decades, the emergence and spread of antibiotic resistance among bacterial pathogens has become a major threat to public health. Bacteria can acquire antibiotic resistance genes by the mobilization and transfer of resistance genes from a donor strain.
openaire +2 more sources
Food substances alter gut resistome: Mechanisms, health impacts, and food components. [PDF]
Abstract Antibiotics are effective in treating bacterial infections, but their widespread use has spurred antibiotic resistance, which is linked closely with human disease. While dietary components are known to influence the gut microbiome, specific effects on the gut resistome—the collection of antibiotic‐resistant genes in the gut ...
Liang Z +5 more
europepmc +3 more sources
Antibiotics and the developing infant gut microbiota and resistome [PDF]
The microbial communities colonizing the human gut are tremendously diverse and highly personal. The composition and function of the microbiota play important roles in human health and disease, and considerable research has focused on understanding the ecological forces shaping these communities. While it is clear that factors such as diet, genotype of
Molly K, Gibson +2 more
openaire +2 more sources
Abundance and diversity of resistomes differ between healthy human oral cavities and gut
Antimicrobial resistance (AMR) represents a global health threat. Here, the authors analyse the oral and gut resistomes from metagenomes of diverse populations and find that the oral resistome harbours higher abundance but lower diversity of ...
Victoria R. Carr +7 more
doaj +1 more source
Rapid resistome mapping using nanopore sequencing [PDF]
The emergence of antibiotic resistance in human pathogens has become a major threat to modern medicine. The outcome of antibiotic treatment can be affected by the composition of the gut.
Ellabaan, Mostafa M Hashim +5 more
core +2 more sources
Identification of aminoglycoside and β-lactam resistance genes from within an infant gut functional metagenomic library. [PDF]
The infant gut microbiota develops rapidly during the first 2 years of life, acquiring microorganisms from diverse sources. During this time, significant opportunities exist for the infant to acquire antibiotic resistant bacteria, which can become ...
Fiona Fouhy +8 more
doaj +1 more source
Characterization of wild and captive baboon gut microbiota and their antibiotic resistomes [PDF]
Antibiotic exposure results in acute and persistent shifts in the composition and function of microbial communities associated with vertebrate hosts.
Boolchandani, Manish +9 more
core +2 more sources
Proteomics as the final step in the functional metagenomics study of antimicrobial resistance [PDF]
peer-reviewedThe majority of clinically applied antimicrobial agents are derived from natural products generated by soil microorganisms and therefore resistance is likely to be ubiquitous in such environments.
Cotter, Paul D. +4 more
core +1 more source
Antimicrobial resistance characteristics and fitness of Gram-negative fecal bacteria from volunteers treated with minocycline or amoxicillin. [PDF]
A yearlong study was performed to examine the effect of antibiotic administration on the bacterial gut flora. Gram-negative facultative anaerobic bacteria were recovered from the feces of healthy adult volunteers administered amoxicillin, minocycline or ...
Abu-Oun, M +9 more
core +9 more sources

