Results 31 to 40 of about 7,489 (208)

Differential responses of the gut microbiome and resistome to antibiotic exposures in infants and adults

open access: yesNature Communications, 2023
Despite their crucial importance for human health, there is still relatively limited knowledge on how the gut resistome changes or responds to antibiotic treatment across ages, especially in the latter case.
Xuanji Li   +9 more
doaj   +1 more source

The human gut resistome [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2015
In recent decades, the emergence and spread of antibiotic resistance among bacterial pathogens has become a major threat to public health. Bacteria can acquire antibiotic resistance genes by the mobilization and transfer of resistance genes from a donor strain.
openaire   +2 more sources

Food substances alter gut resistome: Mechanisms, health impacts, and food components. [PDF]

open access: yesCompr Rev Food Sci Food Saf
Abstract Antibiotics are effective in treating bacterial infections, but their widespread use has spurred antibiotic resistance, which is linked closely with human disease. While dietary components are known to influence the gut microbiome, specific effects on the gut resistome—the collection of antibiotic‐resistant genes in the gut ...
Liang Z   +5 more
europepmc   +3 more sources

Antibiotics and the developing infant gut microbiota and resistome [PDF]

open access: yesCurrent Opinion in Microbiology, 2015
The microbial communities colonizing the human gut are tremendously diverse and highly personal. The composition and function of the microbiota play important roles in human health and disease, and considerable research has focused on understanding the ecological forces shaping these communities. While it is clear that factors such as diet, genotype of
Molly K, Gibson   +2 more
openaire   +2 more sources

Abundance and diversity of resistomes differ between healthy human oral cavities and gut

open access: yesNature Communications, 2020
Antimicrobial resistance (AMR) represents a global health threat. Here, the authors analyse the oral and gut resistomes from metagenomes of diverse populations and find that the oral resistome harbours higher abundance but lower diversity of ...
Victoria R. Carr   +7 more
doaj   +1 more source

Rapid resistome mapping using nanopore sequencing [PDF]

open access: yes, 2017
The emergence of antibiotic resistance in human pathogens has become a major threat to modern medicine. The outcome of antibiotic treatment can be affected by the composition of the gut.
Ellabaan, Mostafa M Hashim   +5 more
core   +2 more sources

Identification of aminoglycoside and β-lactam resistance genes from within an infant gut functional metagenomic library. [PDF]

open access: yesPLoS ONE, 2014
The infant gut microbiota develops rapidly during the first 2 years of life, acquiring microorganisms from diverse sources. During this time, significant opportunities exist for the infant to acquire antibiotic resistant bacteria, which can become ...
Fiona Fouhy   +8 more
doaj   +1 more source

Characterization of wild and captive baboon gut microbiota and their antibiotic resistomes [PDF]

open access: yes, 2018
Antibiotic exposure results in acute and persistent shifts in the composition and function of microbial communities associated with vertebrate hosts.
Boolchandani, Manish   +9 more
core   +2 more sources

Proteomics as the final step in the functional metagenomics study of antimicrobial resistance [PDF]

open access: yes, 2015
peer-reviewedThe majority of clinically applied antimicrobial agents are derived from natural products generated by soil microorganisms and therefore resistance is likely to be ubiquitous in such environments.
Cotter, Paul D.   +4 more
core   +1 more source

Antimicrobial resistance characteristics and fitness of Gram-negative fecal bacteria from volunteers treated with minocycline or amoxicillin. [PDF]

open access: yes, 2014
A yearlong study was performed to examine the effect of antibiotic administration on the bacterial gut flora. Gram-negative facultative anaerobic bacteria were recovered from the feces of healthy adult volunteers administered amoxicillin, minocycline or ...
Abu-Oun, M   +9 more
core   +9 more sources

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