Results 131 to 140 of about 5,207 (162)
Distinct characteristics of the gut virome in patients with osteoarthritis and gouty arthritis. [PDF]
J Transl MedChen CM +22 more
europepmc +1 more source
The Gut Virome Database Reveals Age-Dependent Patterns of Virome Diversity in the Human Gut [PDF]
Cell Host and Microbe, 2020 The gut microbiome profoundly affects human health and disease, and their infecting viruses are likely as important, but often missed because of reference database limitations. Here, we (1) built a human Gut Virome Database (GVD) from 2,697 viral particle or microbial metagenomes from 1,986 individuals representing 16 countries, (2) assess its ...
Olivier Zablocki +2 more
exaly +3 more sources
Gut Virome and Inflammatory Bowel Disease [PDF]
Inflammatory Bowel Diseases, 2016 Gut virome has been shown to yield some beneficial effects on humans, being deeply involved in physiology, inflammation, immunity, and disease. Together with transkingdom interactions, it can interplay with genetic variation in the host to establish specific phenotypes. These interactions can lead to phenotypes not observed with either the virus or the
Franco Scaldaferri +2 more
exaly +5 more sources
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Advances and challenges in cataloging the human gut virome
Cell Host and Microbe, 2022The human gut virome, which is often referred to as the "dark matter" of the gut microbiome, remains understudied. A better understanding of the composition and variations of the gut virome across populations is critical for exploring its impact on diseases and health.
Junhua Li +2 more
exaly +3 more sources
Enteric Virome and Carcinogenesis in the Gut
Digestive Diseases and Sciences, 2020Colorectal cancer (CRC) is a leading cause of cancer-related deaths in both the USA and the world. Recent research has demonstrated the involvement of the gut microbiota in CRC development and progression. Microbial biomarkers of disease have focused primarily on the bacterial component of the microbiome; however, the viral portion of the microbiome ...
Cade, Emlet +2 more
openaire +2 more sources
The gut virome in inflammatory bowel diseases
Current Opinion in Virology, 2021Dysbiosis of the microbiome has been extensively studied in inflammatory bowel diseases (IBD). The roles of bacteria and fungi have been studied in detail, but viral communities, an important component of the microbiome, have been less thoroughly investigated. Metagenomics provided a way to fill this gap by using DNA sequencing to enumerate all viruses
Guanxiang Liang +3 more
openaire +2 more sources
Giant oversights in the human gut virome
Gut, 2019We read with interest the paper by Zuo et al ,1 which used deep sequencing to identify gut mucosal virome alterations in individuals with UC. One of many interesting findings reported by the authors was the detection of giant viruses infecting algae and amoeba ( Mimivirus and Chrysochromulina ericina virus).
Thomas D S Sutton +2 more
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HIV, AIDS, and the virome: Gut reactions
Cell Host & Microbe, 2022In 2016 we discovered alterations in the gut bacterial and viral populations in HIV-associated AIDS (Monaco et al., 2016). Herein, I relate the background behind these developments and discuss how they advanced the field and propelled my current research endeavors.
openaire +2 more sources
Progress and prospects of the healthy human gut virome
Current Opinion in Virology, 2021Not all viruses associated with humans cause disease. Non-pathogenic human-infecting viruses are predicted as important for immune system induction and preparation. Phages that infect bacteria are the most abundant predators of the human microbial ecosystem, promoting and maintaining bacterial diversity. Metagenomic analyses of the human gut virome and
Stephen R Stockdale, Colin Hill
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