Results 161 to 170 of about 244,292 (300)

Epidemiological evidence for the role of puberty and immune senescence in Hodgkin lymphoma aetiology from 1992 Danish cases

open access: yesInternational Journal of Cancer, EarlyView.
What's New? The understanding of the epidemiological and clinical distinctions between Epstein–Barr virus (EBV)‐positive and EBV‐negative classic Hodgkin lymphoma remains incomplete. Here, the authors generated unique sets of population‐based sex‐ and age‐specific incidence rates of classic Hodgkin lymphoma in Denmark stratified by histological subtype
Klaus Rostgaard   +18 more
wiley   +1 more source

GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors [PDF]

open access: bronze, 2011
Beben Benyamin   +14 more
openalex   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng   +4 more
wiley   +1 more source

Exploring the Link Between Psoriasis and Genetic Predictors of Cardiac Magnetic Resonance Traits: A Bidirectional Mendelian Randomization Study

open access: yesiNew Medicine, EarlyView.
ABSTRACT Psoriasis is a chronic autoimmune disease characterized by systemic inflammation and skin involvement, affecting millions of individuals worldwide. However, few studies have evaluated whether psoriasis and cardiac magnetic resonance imaging (CMR) traits share a common genetic basis.
Junlin Yang   +8 more
wiley   +1 more source

Genetic and environmental influences on sleep quality, ability to settle, and crying duration in 2‐ and 5‐month‐old infants: A longitudinal twin study

open access: yesJCPP Advances, EarlyView.
This study found that genetic factors largely influence crying duration and settle ability in infancy, while shared environmental factors primarily affect the number of night wakeups. Etiological influences tended to change from 2 to 5 months, reflecting a highly plastic period in infant brain development and in child‐environment interactions. Abstract
Charlotte Viktorsson   +5 more
wiley   +1 more source

Young adult self‐harm: The role of victimisation and polygenic risk in a population‐based longitudinal study

open access: yesJCPP Advances, EarlyView.
Abstract Background Victimisation has been associated with self‐harm (with or without suicidal intent), but little is known about this association during young adulthood—a distinct developmental period. Further, not all individuals who experience victimisation will later engage in self‐harm, suggesting the influence of other factors.
Filip Marzecki   +8 more
wiley   +1 more source

Investigating the impact of early adversity on perceived support from parents and friends in preadolescence: Do genetic predispositions and timing of exposure matter?

open access: yesJCPP Advances, EarlyView.
This study found that youth with a higher genetic risk for internalizing and externalizing problems were more likely to face adversity within their home, highlighting the need for risk mitigation. These associations varied by adversity type and timing. Additionally, low family income, parental divorce, and externalizing behaviours were linked to lower ...
Christina Y. Cantave   +3 more
wiley   +1 more source

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou   +6 more
wiley   +1 more source

Genome‐wide association study of periodontitis severity and progression

open access: yesJournal of Periodontology, EarlyView.
Abstract Background To add to the knowledge base of periodontal genomics, we carried out a genome‐wide association study (GWAS) of periodontitis severity and progression among 416 mixed‐ethnicity adult participants of a periodontitis clinical study. Methods Participants were 168 adults (mean age = 50 years, 46% males) with severe periodontitis and 248 ...
Flavia Teles   +12 more
wiley   +1 more source

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