Results 161 to 170 of about 247,905 (333)

Causal effects of reproductive traits on cognitive function: A two‐sample and multivariable mendelian randomization study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Potential associations between reproductive traits and cognitive function have been discovered; however, the results are inconsistent, and the causalities are unclear. This study utilized Mendelian randomization (MR) analysis to assess the causal impact of reproductive traits on cognitive function.
Xia Wang, Yunyun Guo
wiley   +1 more source

Review: A Meta-Analysis of GWAS Studies and Age-Associated Diseases

, 2020
William R. Jeck, Alex P. Siebold, Norman E. Sharpless   +2 more
openalex   +1 more source

Socioeconomic Status Modifies the Risk of Gastric Cancer Through Metabolomic Signature: Evidence From a Prospective Cohort Study

iNew Medicine, EarlyView.
ABSTRACT The role of metabolites in the association between socioeconomic status (SES) and gastric cancer remains unclear. This study seeks to elucidate the role of metabolomics in the association between SES and gastric cancer, as well as to explore potential interactions between metabolic signatures and polygenic risk score (PRS) in the context of ...
Shiyin Meng, Shangxin Zhang, Jing Wang, Zhuoyi Wu, Wenjie Xuan, Jiawei Zhang, Qihong Zhao, Anla Hu, Jing Ni   +8 more
wiley   +1 more source

Genome-Wide Association Study (GWAS) Identifies Key Candidate Genes Associated with Leaf Size in Alfalfa (Medicago sativa L.) [PDF]

, 2023
Ming Xu, Xueqian Jiang, Fei He, Bilig Sod, Tianhui Yang, Fan Zhang, Lili Cong, Ruicai Long, Mingna Li, Xue Wang, Qingchuan Yang, Tiejun Zhang, Junmei Kang   +12 more
openalex   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Additional file 3 of GWAS and co-expression network combination uncovers multigenes with close linkage effects on the oleic acid content accumulation in Brassica napus

, 2020
Min Yao, Mei Guan, Zhenqian Zhang, Qiuping Zhang, Yixin Cui, Hao Chen, Wei Liu, Habib U. Jan, Kai P. Voss‐Fels, Christian R. Werner, Xing He, Zhongsong Liu, Chunyun Guan, Rod J. Snowdon, Wei Hua, Lunwen Qian   +15 more
openalex   +1 more source

Monocytes with trained immunity–like signatures are associated with acute anterior uveitis in ankylosing spondylitis

Interdisciplinary Medicine, EarlyView.
In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun, Lu Zhang, Xinyu Yao, Yunfei Liu, Xin Li, Feng Wen, Yong Dai, Ye Dai, Ziyu Du, Dijie Qiao, Ziwei Meng, Cong Hu, Chun Yan, Wei Chi   +13 more
wiley   +1 more source

Editorial: the applications of new multi-locus GWAS methodologies in the genetic dissection of complex traits [PDF]

, 2019
Dunwell, Jim M., Jia, Zhenyu, Zhang, Yuan-Ming   +2 more
core   +2 more sources

Exploring the Relationship Between MDM4 Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case–Control Study

Journal of Clinical Laboratory Analysis, EarlyView.
Our findings indicated that the rs4245739 A>C polymorphism was not associated with BC risk in the Bangladeshi population, whereas the rs1380576 C>G polymorphism was significantly associated with BC risk. This study provides new insights into the genetic factors influencing breast cancer susceptibility in the Bangladeshi population, highlighting the ...
J. M. Aousiful Islam, Sharif Ahamed, Shafiqul Islam, M. Mahboob Hossain, Md Sadbean Hossain, Md. Shaki Mostaid, Md. Rabiul Islam, Md. Aminul Haque   +7 more
wiley   +1 more source

Association of Lactate with Risk of Cardiovascular Diseases: A Two-Sample Mendelian Randomization Study

Vascular Health and Risk Management
Xindi Chang,* Wang Zheng,* Yingli Zhao, Wangkang Niku, Bing Deng, Ping Liu, Yiru Wang Department of Cardiology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China*These authors ...
Chang X, Zheng W, Zhao Y, Niku W, Deng B, Liu P, Wang Y   +6 more
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