Results 171 to 180 of about 283,327 (339)

Meta-GWAS of lumbar spinal disorders

, 2020
Pradeep Suri
openalex   +2 more sources

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study

, 2022
C.G. Downie, S.F. Dimos, S.A. Bien, Y. Hu, B.F. Darst, L.M. Polfus, Y. Wang, G.L. Wojcik, R. Tao, L.M. Raffield, N.D. Armstrong, H.G. Polikowsky, J.E. Below, A. Correa, M.R. Irvin, L.J.F. Rasmussen-Torvik, C.S. Carlson, L.S. Phillips, S. Liu, J.S. Pankow, S.S. Rich, J.I. Rotter, S. Buyske, T.C. Matise, K.E. North, C.L. Avery, C.A. Haiman, R.J.F. Loos, C. Kooperberg, M. Graff, H.M. Highland   +30 more
openalex   +1 more source

Single-cell deconvolution of 3,000 post-mortem brain samples for eQTL and GWAS dissection in mental disorders [PDF]

, 2021
Yongjin Park, Liang He, José Dávila-Velderrain, Lei Hou, Shahin Mohammadi, Hansruedi Mathys, Zhuyu Peng, David A. Bennett, Li‐Huei Tsai, Manolis Kellis   +9 more
openalex   +1 more source

Integrated trajectories of systolic and diastolic function differentially associate with risk for heart failure with preserved and reduced ejection fraction and proteomic profiles

European Journal of Heart Failure, EarlyView.
Graphical overview of derivation and testing of multiparametric trajectories of cardiac function. This study identified six trajectories of LV systolic and diastolic function from mid‐ to late‐life. Predicted trajectory from single echocardiogram identified four trajectories at differential risk for HFpEF and HFrEF.
Anne Marie Reimer Jensen, James C. Ross, Victoria Arthur, Michael E. Hall, Kunihiro Matsushita, Brandon Lennep, Pamela L. Lutsey, Tor Biering‐Sørensen, Amil M. Shah   +8 more
wiley   +1 more source

Genetic Overlap Between Obstructive Sleep Apnea and Ischemic Stroke: A Large-Scale Genome-Wide Cross-Trait Analysis

Nature and Science of Sleep
Wanqing Lin,1,2,* Zhiyi Zhang,3,* Chenlin Wang,4 Yingling Ye,4 Lingrong Zheng,4 Qianqian Hu,4 Renyu Yu,1 Mingxia Wu,4,5 Bin Chen1 1Department of Rehabilitation Medicine and National Clinical Research Base of Traditional Chinese Medicine, The ...
Lin W, Zhang Z, Wang C, Ye Y, Zheng L, Hu Q, Yu R, Wu M, Chen B   +8 more
doaj  

Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS [PDF]

, 2017
Erdogan Taskesen, Aniket Mishra, Sophie van der Sluis, Raffaele Ferrari, D. G. Hernandez, M. A. Nalls, Jonathan D. Rohrer, Adaikalavan Ramasamy, John B. Kwok, Carol Dobson‐Stone, Peter R. Schofield, Glenda M. Halliday, J. R. Hodges, Olivier Piguet, Lauren Bartley, Emma E. Thompson, Eric Haan, Israel Alejandro Quijano-Hernández, Agustı́n Ruiz, Merçé Boada, Barbara Borroni, Alessandro Padovani, Carlos Cruchaga, Nigel J. Cairns, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Gianluigi Forloni, Diego Albani, Daniela Galimberti, Chiara Fenoglio, María Serpente, Elio Scarpini, Jordi Clarimón, Alberto Lleó, Rafael Blesa, María Landqvist Waldö, Kristina Nilsson, Christer Nilsson, I. R. A. Mackenzie, Ging‐Yuek Robin Hsiung, David Mann, Jordan Grafman, Christopher M. Morris, Johannes Attems, Timothy D. Griffiths, Ian G. McKeith, Alan Thomas, Pietro Pietrini, Edward D. Huey, Eric M. Wassermann, Atik Baborie, Evelyn Jaros, Michael Tierney, Pau Pástor, Cristina Razquín, Sara Ortega‐Cubero, Elena Alonso, Robert Perneczky, Janine Diehl‐Schmid, Panagiotis Alexopoulos, Andrea Kurz, Innocenzo Rainero, Elisa Rubino, Lorenzo Pinessi, Ekaterina Rogaeva, Peter St George‐Hyslop, Giacomina Rossi, Fabrizio Tagliavini, Giorgio Giaccone, James B. Rowe, Johannes C. M. Schlachetzki, James Uphill, J. Collinge, Simon Mead, Adrian Danek, Vivianna M. Van Deerlin, Murray Grossman, John Q. Trojanowski, Julie van der Zee, Christine Van Broeckhoven, Stefano F. Cappa, Isabelle Leber, Didier Hannequin, Véronique Golfier, Martine Vercelletto, Alexis Brice, Benedetta Nacmias, Sandro Sorbi, Silvia Bagnoli, Irene Piaceri, Jens Høiriis Nielsen, L. E. Hjermind, Markus J. Riemenschneider, Manuel Mayhaus, Bernd Ibach, Gilles Gasparoni, Sabrina Pichler, Wei Gu, Martin N. Rossor   +99 more
openalex   +1 more source

Deep phenotyping of heart failure with preserved ejection fraction through multi‐omics integration

European Journal of Heart Failure, EarlyView.
Deep phenotyping of of heart failure with preserved ejection fraction (HFpEF) through multi‐omics integration. AI, artificial intelligence. Aims Heart failure with preserved ejection fraction (HFpEF) has become the predominant form of heart failure and a leading cause of global cardiovascular morbidity and mortality.
Jakob Versnjak, Titus Kuehne, Pauline Fahjen, Nina Jovanovic, Ulrike Löber, Gabriele G. Schiattarella, Nicola Wilck, Holger Gerhardt, Dominik N. Müller, Frank Edelmann, Philipp Mertins, Roland Eils, Michael Gotthardt, Sofia K. Forslund, Benjamin Wild, Marcus Kelm   +15 more
wiley   +1 more source

Integrating eQTL and GWAS data characterises established and identifies novel migraine risk loci [PDF]

, 2023
Ammarah Ghaffar, Dale R. Nyholt
openalex   +1 more source

Unsupervised machine learning for cardiovascular disease: A framework for future studies

European Journal of Heart Failure, EarlyView.
Unsupervised machine learning can improve the characterization and stratification of patients with cardiovascular diseases (CVDs). Clustering algorithms, which group patients based on patterns in clinical data, can reveal distinct subgroups that may differ in prognosis and treatment response.
Emmanuel Bresso, Claire Lacomblez, Kévin Duarte, Luca Monzo, Guillaume Baudry, Jasper Tromp, Abhinav Sharma, Nicolas Girerd   +7 more
wiley   +1 more source

Additional file 2 of An RTM-GWAS procedure reveals the QTL alleles and candidate genes for three yield-related traits in upland cotton

, 2020
Junji Su, Caixiang Wang, Qi Ma, Ai Zhang, Chunhui Shi, Juanjuan Liu, Xianliang Zhang, Delong Yang, Xiongfeng Ma   +8 more
openalex   +1 more source