Results 11 to 20 of about 247,905 (333)

HAPPI GWAS: Holistic Analysis with Pre and Post Integration GWAS [PDF]

Bioinformatics, 2020
AbstractMotivationAdvanced publicly available sequencing data from large populations have enabled in-formative genome-wide association studies (GWAS) that associate SNPs with phenotypic traits of interest. Many publicly available tools able to perform GWAS have been developed in response to increased demand.
Marianne L Slaten, Yen On Chan, Vivek Shrestha, Alexander E Lipka, Ruthie Angelovici   +4 more
openaire   +2 more sources

Using the power of innate immunoprofiling to understand vaccine design, infection, and immunity

Human Vaccines & Immunotherapeutics, 2023
In the field of immunology, a systems biology approach is crucial to understanding the immune response to infection and vaccination considering the complex interplay between genetic, epigenetic, and environmental factors.
Jennifer Connors, Gina Cusimano, Nathan Mege, Kyra Woloszczuk, Emily Konopka, Matthew Bell, David Joyner, Jennifer Marcy, Virginie Tardif, Michele A. Kutzler, Roshell Muir, Elias K. Haddad   +11 more
doaj   +1 more source

Genetic Basis Dissection for Eating and Cooking Qualities of Japonica Rice in Northeast China

Agronomy, 2020
The japonica rice in Northeast China is famous because of its high quality. Eating and cooking qualities (ECQs) are the most important factors that determine cooked rice quality.
Yaolong Yang, Xin Xu, Mengchen Zhang, Qun Xu, Yue Feng, Xiaoping Yuan, Hanyong Yu, Yiping Wang, Xinghua Wei   +8 more
doaj   +1 more source

Beyond the coding genome: non-coding mutations and cancer

Frontiers in Bioscience-Landmark, 2020
Latest advancements in genomics involving individuals from different races and geographical locations has led to the identification of thousands of common as well as rare genetic variants and copy number variations (CNVs). These studies have surprisingly
Kaivalya Walavalkar, Dimple Notani
doaj   +1 more source

A Multiple-Trait Bayesian Variable Selection Regression Method for Integrating Phenotypic Causal Networks in Genome-Wide Association Studies

G3: Genes, Genomes, Genetics, 2020
Bayesian regression methods that incorporate different mixture priors for marker effects are used in multi-trait genomic prediction. These methods can also be extended to genome-wide association studies (GWAS).
Zigui Wang, Deborah Chapman, Gota Morota, Hao Cheng   +3 more
doaj   +1 more source

Genome-Wide Association Analysis of Plant Height Using the Maize F1 Population

Plants, 2019
Drastic changes in plant height (PH) are observed when maize adapt to a higher plant density. Most importantly, PH is an important factor affecting maize yield.
Yong Zhang, Jiyu Wan, Lian He, Hai Lan, Lujiang Li   +4 more
doaj   +1 more source

Genome-wide Studies of knee Osteoarthritis: Review [PDF]

Travmatologiâ i Ortopediâ Rossii, 2021
Background. Knee osteoarthritis (OA) is a multifactorial disease resulting from the interaction of many environmental, epigenetic and genetic risk factors, and the latter account for 40% to 65%.
Vitaly B. Novakov, Olga N. Novakova, Mikhail I. Churnosov   +2 more
doaj   +1 more source

Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis [PDF]

, 2020
Background A non-invasive method to grade the severity of steatohepatitis and liver fibrosis is magnetic resonance imaging (MRI) based corrected T1 (cT1).
Banerjee, R, Banerjee, R, Bell, J.D., Bell, J.D., Hemingway, H., Hemingway, H., Hingorani, A.D., Hingorani, A.D., Kelly, M., Kelly, M., McGonigle, J., McGonigle, J., Neubauer, S., Neubauer, S., Nicholls, R.C., Nicholls, R.C., Parisinos, C.A., Parisinos, C.A., Patel, R.S., Patel, R.S., Thomas, E.L., Thomas, E.L., Wilman, H., Wilman, H., Yaghootkar, H., Yaghootkar, H.   +25 more
core   +3 more sources

Single-Step Genome-Wide Association Study for Resistance to Piscirickettsia salmonis in Rainbow Trout (Oncorhynchus mykiss)

G3: Genes, Genomes, Genetics, 2019
One of the main pathogens affecting rainbow trout (Oncorhynchus mykiss) farming is the facultative intracellular bacteria Piscirickettsia salmonis. Current treatments, such as antibiotics and vaccines, have not had the expected effectiveness in field ...
Agustin Barria, Rodrigo Marín-Nahuelpi, Pablo Cáceres, María E. López, Liane N. Bassini, Jean P. Lhorente, José M. Yáñez   +6 more
doaj   +1 more source

POPULATION STRUCTURE AND GENOME-WIDE ASSOCIATION ANALYSIS FOR SALINITY TOLERANCE IN BREAD WHEAT USING SNP, SSR AND SCOT MARKER ASSAYS [PDF]

Arab Universities Journal of Agricultural Sciences, 2020
Wheat is an essential staple food in the developing world, where demand is projected to grow exponentially in the future; simultaneously, climate changes are projected to reduce supply in the near future. One of the main consequences of climate change is
Alsamman Alsamman, S.D. Ibrahim, Mohamed Rashed, Ayman Atta, M.S. Ahmed, Alaa Hamwieh   +5 more
doaj   +1 more source