Results 21 to 30 of about 256,390 (380)
GWAS in the southern African context [PDF]
PLOS ONE, 2022 Researchers would generally adjust for the possible confounding effect of population structure by considering global ancestry proportions or top principle components. Alternatively, researchers would conduct admixture mapping to increase the power to detect variants with an ancestry effect.
Yolandi Swart +5 more
openaire +4 more sources
Investigating the genetic architecture of non-cognitive skills using GWAS-by-subtraction
Nature Genetics, 2021 Little is known about the genetic architecture of traits affecting educational attainment other than cognitive ability. We used genomic structural equation modeling and prior genome-wide association studies (GWASs) of educational attainment (n = 1,131 ...
F. Dostoyevsky +27 more
semanticscholar +1 more source
G3: Genes, Genomes, Genetics, 2020 The natural genetic diversity of agricultural species is an essential genetic resource for breeding programs aiming to improve their ecosystem and production services.
Thomas Keep +13 more
doaj +1 more source
Nature Communications, 2021 Genetic factors are recognized to contribute to peptic ulcer disease (PUD) and other gastrointestinal diseases, such as gastro-oesophageal reflux disease (GORD), irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).
Yeda Wu +5 more
semanticscholar +1 more source
G3: Genes, Genomes, Genetics, 2020 Bayesian regression methods that incorporate different mixture priors for marker effects are used in multi-trait genomic prediction. These methods can also be extended to genome-wide association studies (GWAS).
Zigui Wang +3 more
doaj +1 more source
Genome-Wide Association Analysis of Plant Height Using the Maize F1 Population
Plants, 2019 Drastic changes in plant height (PH) are observed when maize adapt to a higher plant density. Most importantly, PH is an important factor affecting maize yield.
Yong Zhang +4 more
doaj +1 more source
G3: Genes, Genomes, Genetics, 2020 Exercise is recommended by health professionals across the globe as part of a healthy lifestyle to prevent and/or treat the consequences of obesity. While overall, the health benefits of exercise and an active lifestyle are well understood, very little ...
Louis P. Watanabe +3 more
doaj +1 more source
Reducing GWAS Complexity [PDF]
Cell Cycle, 2016 Genome-wide association studies (GWAS) have revealed numerous genomic 'hits' associated with complex phenotypes. In most cases these hits, along with surrogate genetic variation as measure by numerous single nucleotide polymorphisms (SNPs) that are in linkage disequilibrium, are not in coding genes making assignment of functionality or causality ...
Rosalind A. Eeles +8 more
openaire +3 more sources
Deriving GWAS summary estimates for paternal smoking in UK biobank: a GWAS by subtraction [PDF]
BMC Research Notes, 2023 Abstract Objective To use genome-wide association study (GWAS) by subtraction, a method for deriving novel GWASs from existing summary statistics, to derive genome-wide summary statistics for paternal smoking. Result A GWAS by subtraction was implemented using a weighted ...
Benjamin Woolf +3 more
openaire +4 more sources
Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules [PDF]
, 2017 Motivation: Network-based genome-wide association studies (GWAS) aim to identify functional modules from biological networks that are enriched by top GWAS findings.
Alzheimer’s Disease Neuroimaging Initiative +10 more
core +1 more source