Results 21 to 30 of about 13,532,360 (331)

Parkinson’s disease-associated ATP13A2/PARK9 functions as a lysosomal H+,K+-ATPase

Nature Communications, 2023
Mutations in the human ATP13A2 (PARK9), a lysosomal ATPase, cause Kufor-Rakeb Syndrome, an early-onset form of Parkinson’s disease (PD). Here, we demonstrate that ATP13A2 functions as a lysosomal H+,K+-ATPase.
Takuto Fujii, Shushi Nagamori, Pattama Wiriyasermkul, Shizhou Zheng, Asaka Yago, Takahiro Shimizu, Yoshiaki Tabuchi, Tomoyuki Okumura, Tsutomu Fujii, Hiroshi Takeshima, Hideki Sakai   +10 more
doaj   +1 more source

Sistemas primários de transporte de prótons integram os mecanismos de desintoxicação do mesotrione em plantas de milho Proton transport primary systems used as mechanisms of mesotrione detoxification in corn plants

Planta Daninha, 2009
O mesotrione é um dos mais efetivos herbicidas desenvolvidos para o controle de uma ampla gama de plantas daninhas que infestam campos de milho (Zea mays).
J. Ogliari, S.P. Freitas, A.C. Ramos, R.E. Bressan Smith, A.R. Façanha   +4 more
doaj   +1 more source

Extra-renal locations of the a4 subunit of H+ATPase [PDF]

, 2016
Background Vacuolar-type proton pumps help maintain acid–base homeostasis either within intracellular compartments or at specialised plasma membranes. In mammals they are made up of 13 subunits, which form two functional domains. A number
Golder, Zoe J, Karet Frankl, Fiona E
core   +10 more sources

Early salinity response in root of salt sensitive Olea europaea L. cv Leccino

Plant Stress, 2023
The present study evaluates the molecular mechanisms involved, under salt stress, in the roots of Olea europaea L. cultivar Leccino (salt sensitive).
Mirko Sodini, Alessandra Francini, Luca Sebastiani   +2 more
doaj   +1 more source

The parietal cell gastric H, K-ATPase also functions as the Na, K-ATPase and Ca-ATPase in altered states [v2; ref status: indexed, http://f1000r.es/1tc]

F1000Research, 2013
This article offers an explanation for the apparent lack of Na, K-ATPase activity in parietal cells although ouabain has been known to inhibit gastric acid secretion since 1962.
Tushar Ray
doaj   +1 more source

Modulation of iron responsive gene expression and enzymatic activities in response to changes of the iron nutritional status in _Cucumis sativus_ L. [PDF]

, 2010
Regulation exerted by the iron status of the plant on the iron deficiency responses was investigated in cucumber roots (_Cucumis sativus_ L.) both at the biochemical and molecular level. Absence of iron induced the expression of the CsFRO1, CsIRT1, CsHA1
Gianpiero Vigani, Graziano Zocchi, Patrizia De Nisi   +2 more
core   +2 more sources

Maintenance of mesophyll potassium and regulation of plasma membrane H+-ATPase are associated with physiological responses of tea plants to drought and subsequent rehydration

Crop Journal, 2018
Drought stress is one of the main factors limiting yield in tea plants. The plant cell's ability to preserve K+ homeostasis is an important strategy for coping with drought stress.
Xianchen Zhang, Honghong Wu, Linmu Chen, Linlin Liu, Xiaochun Wan   +4 more
doaj   +1 more source

Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase [PDF]

, 2016
Breast cancer is the most common type of cancer affecting women. Despite the good prognosis when detected early, significant challenges remain in the treatment of metastatic breast cancer.
Blumwald, Bowman, Bowman, Brock, Capaccioli, Choi, Choi, Côrte-Real, Deng, Fais, Farina, Forgac, Forgac, García-García, Iwatsuki, Kano, Kanwar, Khundmiri, Krissansen, Liu, Martínez-Zaguilán, Mu, Mutharasan, Müller, Ohkumaji, Parra, Pierce, Pouyssegur, Randall, Rascón-Cruz, Rodrigues, Rodrigues, Rodrigues, Sanderson, Srinivas, Tsuda, Ullrich, Varadhachary, Vollmar, Vollmar, Wieczorek, Yokoyama, Yokoyama, Zhou, Zhou   +44 more
core   +3 more sources

The Ca2+ Sensor SCaBP3/CBL7 Modulates Plasma Membrane H+-ATPase Activity and Promotes Alkali Tolerance in Arabidopsis

The Plant Cell, 2019
The Ca2+ sensor SCaBP3 promotes the self-inhibition of plasma membrane H+-ATPase and is involved in the response to alkaline stress in Arabidopsis. Saline-alkali soil is a major environmental constraint impairing plant growth and crop productivity.
Yongqing Yang, Yujiao Wu, Liang Ma, Zhijia Yang, Qiuyan Dong, Qinpei Li, Xuping Ni, J. Kudla, Chunpeng Song, Yan Guo   +9 more
semanticscholar   +1 more source

Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes [PDF]

, 2017
The vacuolar-type H+-translocating ATPase (v-H+-ATPase) has been implicated in the amino aciddependent activation of the mechanistic target of rapamycin complex 1 (MTORC1), an important regulator of macroautophagy. To reveal the mechanistic links between
Damme, Markus, De Brabander, Jef K., Eskelinen, Eeva-Liisa, Haas, Albert, Heeren, Joerg, Ichihara, Atsuhiro, Jabs, Sabrina, Kissing, Sandra, Kornak, Uwe, Luellmann-Rauch, Renate, Rudnik, Soenke, Saftig, Paul   +11 more
core   +2 more sources