Results 1 to 10 of about 33,619 (164)

Coordination and Management of COVID-19 in Africa through Health Operations and Technical Expertise Pillar: A Case Study from WHO AFRO One Year into Response [PDF]

Tropical Medicine and Infectious Disease, 2022
Background: following the importation of the first Coronavirus disease 2019 (COVID-19) case into Africa on 14 February 2020 in Egypt, the World Health Organisation (WHO) regional office for Africa (AFRO) activated a three-level incident management ...
Nsenga Ngoy, Ishata Nannie Conteh, Boniface Oyugi, Patrick Abok, Aminata Kobie, Peter Phori, Cephas Hamba, Nonso Ephraim Ejiofor, Kaizer Fitzwanga, John Appiah, Ama Edwin, Temidayo Fawole, Rashidatu Kamara, Landry Kabego Cihambanya, Tasiana Mzozo, Caroline Ryan, Fiona Braka, Zabulon Yoti, Francis Kasolo, Joseph C. Okeibunor, Abdou Salam Gueye   +20 more
doaj   +2 more sources

Longitudinal Monitoring of Systemic Cytokines After Mild Zika Virus Infection Revealed an Association Between Th17 Polarization and Clinical and Serological Outcomes. [PDF]

J Med Virol
ABSTRACT Zika virus (ZIKV) is a neurotropic virus that can cause a variety of neurological manifestations, ranging from mild forms to severe disorders like Guillain–Barré syndrome and congenital Zika syndrome. The pathophysiology of these complications is not fully understood, but they have been linked to host immune responses, particularly a ...
Marquine S, Mura M, de Laval F, Grard G, Badaut C, Briolant S, Trignol A.   +6 more
europepmc   +2 more sources

Comparative Efficacy and Safety of Anakinra and Canakinumab in Patients With VEXAS Syndrome: An International Multicenter Study. [PDF]

Arthritis Rheumatol
Objective The aim of this study was to compare differences in clinical response, drug survival, and adverse event rates between anakinra and canakinumab in VEXAS (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) syndrome. Methods This multicenter international study includes patients with VEXAS from France, Israel, and Italy treated with ...
Eviatar T, Capelusnik D, Campochiaro C, Lacombe V, Jachiet V, Zisapel M, Sagy I, Tayer-Shifman OE, Ozeri D, Kivity S, Tomelleri A, Terrier B, Peleg H, Comont T, Sacre K, Woaye-Hune P, Arnaud L, Lazaro E, Grobost V, Lifermann F, Samson M, Ardois S, Garnier A, Maria A, Cantagrel A, Meyer A, Bouaziz JD, Heiblig M, Dagna L, Diral E, Kosmider O, Elkayam O, Hadjadj J, Georgin-Lavialle S, Fain O, Mekinian A.   +35 more
europepmc   +2 more sources

Inflammatory Mechanisms of Dysmenorrhea: Novel Insights From Menstrual Effluent in an Adolescent Cohort. [PDF]

BJOG
ABSTRACT Objective To examine how eicosanoid levels in menstrual effluent of adolescents within 3 years of menarche relate to the severity of menstrual pain. Design Prospective cohort study. Setting Community teaching hospital. Population or Sample Adolescents within 3 years after menarche.
Kyathanahalli CN, Tu FF, Hellman KM.
europepmc   +2 more sources

Diapause characterisation and seasonality of Aedes japonicus japonicus (Diptera, Culicidae) in the northeast of France

Parasite, 2021
The invasive mosquito Aedes japonicus japonicus (Theobald, 1901) settled in 2013 in the Alsace region, in the northeast of France. In this temperate area, some mosquito species use diapause to survive cold winter temperatures and thereby foster ...
Krupa Eva, Henon Nicolas, Mathieu Bruno
doaj   +1 more source

Efficiency of human monocyte-derived suppressor cell-based treatment in graft-versus-host disease prevention while preserving graft-versus-leukemia effect

OncoImmunology, 2021
Background Immunosuppressive cell-based therapy is a recent strategy for controlling Graft-versus-Host Disease (GvHD). Such cells ought to maintain their suppressive function in inflammatory conditions and in the presence of immunosuppressive agents ...
Nona Janikashvili, Claire Gérard, Marine Thébault, Andrea Brazdova, Clovis Boibessot, Claudie Cladière, Marion Ciudad, Hélène Greigert, Séthi Ouandji, Thibault Ghesquière, Maxime Samson, Sylvain Audia, Philippe Saas, Bernard Bonnotte   +13 more
doaj   +1 more source

Tradutor: o inescapável hôte da língua do Outro The translator: the inescapable hôte of the Other´s language

Trabalhos em Linguística Aplicada, 2011
A partir de algumas concepções de língua, tradução e hospitalidade desenvolvidas pelo filósofo francês Jacques Derrida, pretende-se, neste trabalho, estabelecer uma relação entre as considerações derridianas sobre a tradução do termo francês hôte ...
Erica Lima
doaj   +1 more source

CRISPR Interference of a Clonally Variant GC-Rich Noncoding RNA Family Leads to General Repression of var Genes in Plasmodium falciparum

mBio, 2020
The human malaria parasite Plasmodium falciparum uses mutually exclusive expression of the PfEMP1-encoding var gene family to evade the host immune system. Despite progress in the molecular understanding of the default silencing mechanism, the activation
Anna Barcons-Simon, Carlos Cordon-Obras, Julien Guizetti, Jessica M. Bryant, Artur Scherf   +4 more
doaj   +1 more source

Predictive biomarkers and specific immune responses of COVID-19 mRNA vaccine in patients with cancer: prospective results from the CACOV-VAC trial

BMJ Oncology, 2023
Objective Vaccinated patients with cancer in follow-up studies showed a high seropositivity rate but impaired antibody titres and T cell responses following mRNA vaccine against COVID-19.
Laura Mansi, Olivier Adotevi, Marie Kroemer, Laurie Spehner, Adeline Bouard, Marine Jary, Romain Loyon, Christophe Borg, Dewi Vernerey, Syrine Abdeljaoued, Myriam Ben Khelil, Quentin Lepiller, Emeline Orillard, Antoine Falcoz, Hamadi Almotlak, Stefano Kim, Elsa Curtit, Guillaume Meynard, Charlee Nardin, Kamal Asgarov, Ugo Chartral, Virginie Mougey, Morgane Lopez   +22 more
doaj   +1 more source

Selective Production of 9R-Hydroxy-10E,12Z,15Z-Octadecatrienoic Acid from α-Linolenic Acid in Perilla Seed Oil Hydrolyzate by a Lipoxygenase from Nostoc Sp. SAG 25.82. [PDF]

PLoS ONE, 2015
Hydroxy fatty acids (HFAs) derived from omega-3 polyunsaturated fatty acids have been known as versatile bioactive molecules. However, its practical production from omega-3 or omega-3 rich oil has not been well established.
Kyoung-Rok Kim, Jung-Ung An, Seon-Hwa Lee, Deok-Kun Oh   +3 more
doaj   +1 more source