Results 281 to 290 of about 717,888 (354)

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Expression of blood group antigen (A, B, H, Le^a, Le^b) on liver allografts [PDF]

, 1992
Hayashi, S, Iwaki, Y, Noguchi, K, Starzl, TE, Yagihashi, A   +4 more
core  

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Establishment and Application of a Novel Protein Microarray for Serological Detection and Differentiation of Senecavirus A. [PDF]

Transbound Emerg Dis
Li D, Deng J, Wang Z, Zhang Y, Li Y, Hao L, Tian K, Li X.   +7 more
europepmc   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Naturally acquired antibodies to <i>Plasmodium vivax</i> Pv_LISP-2, a potential liver stage vaccine antigen. [PDF]

Front Immunol
Donassolo RA, Soares da Veiga GT, Nisimura LM, Bittencourt NC, Salazar YEAR, Barros DKADS, Lopes SCP, de Sousa TN, Costa FTM, Albrecht L.   +9 more
europepmc   +1 more source

Helminth Antigens Modulate Virus-Induced Activation of CD154 (CD40L) Expression on T Cells in Onchocerca volvulus-Infected Individuals. [PDF]

Pathogens
Fogang BAN, Arndts K, Adjobimey T, Owusu M, Opoku VS, Adu Mensah D, Boateng J, Osei-Mensah J, Meyer J, Klarmann-Schulz U, Horn S, Kroidl I, Debrah AY, Hoerauf A, Ritter M, Debrah LB.   +15 more
europepmc   +1 more source

Mutations outside the MR1 antigen binding groove differentially inhibit presentation of exogenous antigens. [PDF]

J Biol Chem
Kulicke CA, Lemon C, Krawic JR, Nieto Ramirez LM, Kim SJ, Narayanan G, Tafesse FG, Hildebrand WH, Dobos KM, Lewinsohn DM.   +9 more
europepmc   +1 more source

Glycan-binding specificities of anti-ABO(H) antibodies and lectins. [PDF]

Transfusion
Hamm P, Mehta AY, Charon KM, Heimburg-Molinaro J, Tulin EKC, Stowell SR, Yeung MY, Lane WJ, Cummings RD, Hollenhorst MA.   +9 more
europepmc   +1 more source