Results 91 to 100 of about 12,258 (237)

VivosX, a disulfide crosslinking method to capture site-specific, protein-protein interactions in yeast and human cells

open access: yeseLife, 2018
VivosX is an in vivo disulfide crosslinking approach that utilizes a pair of strategically positioned cysteines on two proteins to probe physical interactions within cells.
Chitra Mohan   +6 more
doaj   +1 more source

Finding balance: the dynamic interplay between H3K27me3 writers and erasers in regulating environmental plasticity and memory

open access: yesNew Phytologist, Volume 249, Issue 5, Page 2241-2250, March 2026.
Summary Subject to an ever‐changing world, plants must respond to harmful conditions and environmental fluctuations. Their evolutionary success can be attributed to their plasticity in both perceiving and integrating these variations to facilitate adaptation.
Rory Osborne
wiley   +1 more source

How does evolution tune biological noise? [PDF]

open access: yes, 2014
International audiencePart of molecular and phenotypic differences between individual cells, between body parts, or between individuals can result from biological noise.
Richard, Magali, Yvert, Gaël
core   +5 more sources

Beyond bacterial defences: the role of lysozyme in cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang   +4 more
wiley   +1 more source

Slx5/Slx8-dependent ubiquitin hotspots on chromatin contribute to stress tolerance [PDF]

open access: yes, 2019
Chromatin is a highly regulated environment, and protein association with chromatin is often controlled by post-translational modifications and the corresponding enzymatic machinery.
Habermann, B.   +6 more
core   +3 more sources

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 409-422, 15 January 2026.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert   +3 more
wiley   +1 more source

The Schizosaccharomyces pombe JmjC-protein, Msc1, prevents H2A.Z localization in centromeric and subtelomeric chromatin domains. [PDF]

open access: yesPLoS Genetics, 2009
Eukaryotic genomes are repetitively packaged into chromatin by nucleosomes, however they are regulated by the differences between nucleosomes, which establish various chromatin states.
Luke Buchanan   +10 more
doaj   +1 more source

Versatile toolbox for high throughput biochemical and functional studies with fluorescent fusion proteins [PDF]

open access: yes, 2012
Fluorescent fusion proteins are widely used to study protein localization and interaction dynamics in living cells. However, to fully characterize proteins and to understand their function it is crucial to determine biochemical characteristics such as ...
Hake, Sandra B.   +3 more
core   +4 more sources

Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning.

open access: yesPLoS Biology, 2005
H2A.Z is an evolutionary conserved histone variant involved in transcriptional regulation, antisilencing, silencing, and genome stability. The mechanism(s) by which H2A.Z regulates these various biological functions remains poorly defined, in part due to
Benoît Guillemette   +6 more
doaj   +2 more sources

Biological noise and H2A.Z: a promising connection for language [PDF]

open access: yesFrontiers in Genetics, 2015
This Document is Protected by copyright and was first published by Frontiers. All rights reserved.
openaire   +4 more sources

Home - About - Disclaimer - Privacy