Results 101 to 110 of about 12,258 (237)
, 2018 Background: The chromatin remodelers of the SWI/SNF family are critical transcriptional regulators. Recognition of lysine acetylation through a bromodomain (BRD) component is key to SWI/SNF function; in most eukaryotes, this function is attributed to ...
Burtch, Alyson +9 more
core +1 more source
Crop biotechnology: prospects and opportunities [PDF]
, 2010 SUMMARYThis paper is a brief review summarizing some of the important areas of activity in crop biotechnology likely to be exploited over the medium term (10–20 years), with an emphasis on agronomic traits.
Dunwell, J. M.
core +1 more source
New Phytologist, Volume 249, Issue 2, Page 930-944, January 2026.Summary Chromatin organization and histone modifications play essential roles in regulating gene expression during development. DEK is a conserved chromatin‐associated protein implicated in DNA topology and transcriptional regulation, yet its in vivo function in plants has remained elusive.
Miyuki Nakamura +8 more
wiley +1 more source
NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis
Nature Communications, 2020 The histone variant H2A.Z is deposited by the SWR1 complex to replace H2A in Arabidopsis, but the mechanism of H2A.Z removal is unclear. Here, the authors show that NRP proteins can regulate gene expression by counteracting SWR1 and prevent excessive ...
Yafei Wang +9 more
doaj +1 more source
Multiple roles of H2A.Z in regulating promoter chromatin architecture in human cells
Nature Communications, 2021 Histone variant H2A.Z has been suggested to contribute to the regulation of promoter accessibility. Here, the authors present high-depth maps of the position and accessibility of H2A.Z-containing nucleosomes for human Pol II promoters and provide ...
Lauren Cole +6 more
doaj +1 more source
Canonical histone H2Ba and H2A.X dimerize in an opposite genomic localization to H2A.Z/H2B.Z dimers in Toxoplasma gondii [PDF]
, 2014 Histone H2Ba of Toxoplasma gondii was expressed as recombinant protein (rH2Ba) and used to generate antibody in mouse that is highly specific. Antibody recognizing rH2Ba detects a single band in tachyzoite lysate of the expected molecular weight (12kDa).
Angel, Sergio O. +6 more
core +2 more sources
The Plant Journal, Volume 125, Issue 2, January 2026.SUMMARY The molecular and genetic mechanisms regulating female germline development remain largely unknown in basal and early‐divergent angiosperms. This contrasts with recent progress in model eudicots such as Arabidopsis thaliana and monocots, such as rice, barley, and maize. In this study, we investigate the genetic pathway governing female germline
Jorge Lora +4 more
wiley +1 more source
Chromatin remodelers and their roles in chromatin organization [PDF]
, 2012 The DNA in the eukaryotic nucleus is organized into a complex DNA-protein structure called chromatin. The basic repeating unit of chromatin is the nucleosome, which consists of 147 bp of DNA wrapped around a histone protein octamer. The nucleosomes
Strålfors, Annelie
core +1 more source
Nuclear destabilisation – a possible genesis of cancer?
Biological Reviews, Volume 100, Issue 6, Page 2420-2434, December 2025.ABSTRACT This review examines the increasingly prominent role of mechanics within cancer formation and progression. The extremely varied and contradictory genetic landscape of cancer is in stark contrast to the seemingly universal mechanical characteristics of cancer cells and their tumour microenvironment, and mechanics may be a principal unifying ...
Daniel D. Scott +4 more
wiley +1 more source
Histone Variant H2A.Z and RNA Polymerase II Transcription Elongation [PDF]
Molecular and Cellular Biology, 2011 Nucleosomes containing histone variant H2A.Z (Htz1) serve to poise quiescent genes for activation and transcriptional initiation. However, little is known about their role in transcription elongation. Here we show that dominant mutations in the elongation genes SPT5 and SPT16 suppress the hypersensitivity of htz1Δ strains to drugs that inhibit ...
Maria Soledad, Santisteban +2 more
openaire +2 more sources