Results 231 to 237 of about 12,258 (237)

Patterning chromatin: form and function for H2A.Z variant nucleosomes

Current Opinion in Genetics & Development, 2006
Although many histone variants are specific to higher eukaryotes, the H2A variant H2A.Z has been conserved during eukaryotic evolution. Genetic studies have demonstrated roles for H2A.Z in antagonizing gene-silencing, chromosome stability and gene activation. Biochemical work has identified a conserved chromatin-remodeling complex responsible for H2A.Z
Ryan M, Raisner, Hiten D, Madhani
openaire   +2 more sources

Reuniting the contrasting functions of H2A.Z.

Biochemistry and cell biology = Biochimie et biologie cellulaire, 2007
It is now well established that cells modify chromatin to set transcriptionally active or inactive regions. Such control of chromatin structure is essential for proper development of organisms. In addition to the growing number of histone post-translational modifications, cells can exchange canonical histones with different variants that can directly ...
Benoît, Guillemette, Luc, Gaudreau
openaire   +1 more source

Histone variant H2A.Z facilitates DNA replication

Science China Life Sciences, 2020
Lei, Qiu, Xinyi, Zeng, Junhong, Han
openaire   +2 more sources

[H2A.Z: a histone variant that decorates gene promoters].

Medecine sciences : M/S, 2007
The nucleosome, fundamental unit of chromatin, is composed of four basic histones, H2A, H2B, H3 and H4, around which DNA is wrapped. In order to have access to DNA, cells must modify the structure of chromatin by different known mechanisms. One such mechanism is by replacing canonical histones in the nucleosome with variants, which can confer special ...
Benoît, Guillemette, Luc, Gaudreau
openaire   +1 more source

Mechanisms of gene regulation by SRCAP and H2A.Z

AbstractDiscriminating regulatory functions of chromatin composition from those of chromatin-modifying complexes is a central problem in gene regulation. This question remains unexplored in the context of histone variants and their dedicated chromatin remodelers.
Armelle Tollenaere, Enes Ugur, Susanna Dalla-Longa, Cédric Deluz, Devin Assenheimer, J Christof M Gebhardt, Heinrich Leonhardt, David M Suter   +7 more
openaire   +1 more source

Faculty Opinions recommendation of H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2013
Yamini Dalal, Delphine Quenet
openaire   +1 more source

Probing the effect of histone variant H2A.Z

Biophysical Journal
Helen K. Moos, Evgenia N. Nikolova
openaire   +1 more source