Arabidopsis SWR1-associated protein methyl-CpG-binding domain 9 is required for histone H2A.Z deposition. [PDF]
Deposition of the histone variant H2A.Z by the SWI2/SNF2-Related 1 chromatin remodeling complex (SWR1-C) is important for gene regulation in eukaryotes, but the composition of the Arabidopsis SWR1-C has not been thoroughly characterized.
Ausin, Israel +11 more
core
Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila
The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause +5 more
wiley +1 more source
The Role of the Histone Variant H2A.Z in Metazoan Development
During the emergence and radiation of complex multicellular eukaryotes from unicellular ancestors, transcriptional systems evolved by becoming more complex to provide the basis for this morphological diversity.
Yasmin Dijkwel, David J. Tremethick
doaj +1 more source
The true story of Yeti, the "abominable" heterochromatic gene of drosophila melanogaster [PDF]
The Drosophila Yeti gene (CG40218) was originally identified by recessive lethal mutation and subsequently mapped to the deep pericentromeric heterochromatin of chromosome 2. Functional studies have shown that Yeti encodes a 241 amino acid protein called
Cuticone, Stefano +5 more
core +1 more source
The environmentally responsive plant epigenome: insights from jasmonate signaling
Summary The environmental responsiveness of the plant epigenome is essential for spatiotemporally precise gene regulation, enabling plants to adapt to external cues. Elucidating the mechanisms underlying this responsiveness is therefore fundamental to deciphering the molecular logic of plant‐environment interactions.
Mark Zander, Emily Vesper
wiley +1 more source
H2A.Z overexpression promotes cellular proliferation of breast cancer cells [PDF]
We recently showed that histone H2A.Z, as well as members of the ATP-dependent p400 chromatin remodeling complex (p400.com), are essential components of estrogen receptor alpha (ERalpha) signaling. More specifically, we showed that H2A.Z and p400.com are incorporated into the promoter regions of ERalpha target genes only upon gene induction, and also ...
Amy, Svotelis +3 more
openaire +2 more sources
Epigenetic regulation of mycorrhizal symbioses: from plastic responses to transgenerational legacies
Summary Mycorrhizal symbioses represent one of the most widespread and ecologically significant plant–microbe interactions, shaping plant nutrition, stress resilience, and ecosystem functioning. Beyond their role in nutrient exchange and systemic defense, growing evidence suggests that these symbioses also influence plant plasticity within and across ...
Gerson Beltrán‐Torres +9 more
wiley +1 more source
The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects. [PDF]
Genome instability is associated with tumorigenesis. Here, we identify a role for the histone Htz1, which is deposited by the Swr1 chromatin-remodeling complex (SWR-C), in preventing genome instability in the absence of the replication fork/replication ...
Branzei, Dana +5 more
core +2 more sources
Integrated GWAS and Fst analysis identify flowering‐time regulatory genes in maize
Abstract Flowering time in maize is a complex quantitative trait regulated by multiple genes, and its genetic variation mechanisms remain to be fully elucidated. In this study, we phenotypically evaluated flowering‐related traits (days to tasseling, days to pollen shedding, days to silking) across six different environments using an association ...
Dong Wang +17 more
wiley +1 more source
DNA Methylation, H2A.Z, and the Regulation of Constitutive Expression [PDF]
The most well-studied function of DNA methylation in eukaryotic cells is the transcriptional silencing of genes and transposons. More recent results showed that many eukaryotes methylate the bodies of genes as well and that this methylation correlates with transcriptional activity rather than repression.
D, Coleman-Derr, D, Zilberman
openaire +2 more sources

