Results 141 to 150 of about 16,350 (151)
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The H3K4me1 histone mark recruits DNA repair to functionally constrained genomic regions in plants
2022Abstract Mutation is the ultimate source of genetic variation. Mutation rate variability has been observed within plant genomes, but the underlying mechanisms have been unclear. We previously found that mutations occur less often in functionally constrained regions of the genome in Arabidopsis ...
Daniela Quiroz +8 more
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H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells
Genome Research, 2015 Acknowledgments: we thank Ronnie Lendrum for manuscript preparation and Tim Triche Jr. for his invaluable advice. This work has been financially supported by the Plan Nacional de I+D+I 2008-2011/2013-2016/ FEDER (PI11/01728 to A.F.F., PI 12/0615 to J.A.R., PI10/0449 to P.M., and PI11/0119 to C.B.); the ISCIII-Subdireccion General de Evaluacion y ...
Corrado Fagnani +2 more
exaly +4 more sources
Biochemical and Biophysical Research Communications
Post-translational modifications of histones play a crucial role in chromatin structure maintenance and epigenetic regulation. The LiveMIEL (Live-cell Microscopic Imaging of Epigenetic Landscape) method represents a promising approach for tracking histone modifications.
Konstantin A Lukyanov +2 more
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Post-translational modifications of histones play a crucial role in chromatin structure maintenance and epigenetic regulation. The LiveMIEL (Live-cell Microscopic Imaging of Epigenetic Landscape) method represents a promising approach for tracking histone modifications.
Konstantin A Lukyanov +2 more
exaly +3 more sources
Biology of Reproduction
Abstract Epigenetic dysregulation in the human endometrium contributes significantly to infertility, and especially to recurrent implantation failure (RIF). Impaired endometrial decidualization is a major cause of RIF, although the underlying epigenetic mechanisms remain unclear.
Qiaoqiao Chen +10 more
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Abstract Epigenetic dysregulation in the human endometrium contributes significantly to infertility, and especially to recurrent implantation failure (RIF). Impaired endometrial decidualization is a major cause of RIF, although the underlying epigenetic mechanisms remain unclear.
Qiaoqiao Chen +10 more
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Cellular Signalling
Dipeptidyl peptidase-4 (DPP4)-targeted therapy is widely employed in the therapy of pulmonary diseases, but the role of its H3K4me1 modification in pulmonary arterial hypertension (PAH) disease remains unknown. This study aims to investigate the function of histone methyltransferase SET domain containing 7 (Set7)-mediated monomethylation of histone 3 ...
Bingyuan Wang, Yilin Xie
exaly +3 more sources
Dipeptidyl peptidase-4 (DPP4)-targeted therapy is widely employed in the therapy of pulmonary diseases, but the role of its H3K4me1 modification in pulmonary arterial hypertension (PAH) disease remains unknown. This study aims to investigate the function of histone methyltransferase SET domain containing 7 (Set7)-mediated monomethylation of histone 3 ...
Bingyuan Wang, Yilin Xie
exaly +3 more sources
H3K4me1 in VTA Mediates Early Life Stress-Induced Stress Sensitivity
Biological Psychiatry, 2021Julie-Anne Rodier, Catherine Pena
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Applied Biochemistry and Biotechnology
Tubal factor infertility (TFI) is one of the most common causes of infertility. TFI may be caused by impaired muscle contractions and ciliary beats. Further study on the molecular mechanism of tubal inflammation and cilia beat frequency is of great clinical significance for improving and preventing TFI.
Liang, Shao +7 more
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Tubal factor infertility (TFI) is one of the most common causes of infertility. TFI may be caused by impaired muscle contractions and ciliary beats. Further study on the molecular mechanism of tubal inflammation and cilia beat frequency is of great clinical significance for improving and preventing TFI.
Liang, Shao +7 more
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Molecular Carcinogenesis
ABSTRACTCutaneous squamous cell carcinoma (cSCC) is a common type of cutaneous cancer globally. M2 macrophage‐derived exosomes (M2 exosomes) facilitate the development of cancer. Ferroptosis, a newly uncovered form of cell death, is linked to cancer progression.
Jun, Yin +6 more
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ABSTRACTCutaneous squamous cell carcinoma (cSCC) is a common type of cutaneous cancer globally. M2 macrophage‐derived exosomes (M2 exosomes) facilitate the development of cancer. Ferroptosis, a newly uncovered form of cell death, is linked to cancer progression.
Jun, Yin +6 more
openaire +2 more sources