Glycosylation of canine tetherin is essential for its antiviral activity against H3N2 canine influenza virus [PDF]
Tetherin is an interferon-induced-expressing transmembrane protein that utilizes a unique topology to restrict the release of enveloped viruses from the surface of the cell membrane.
Liang Xu +17 more
doaj +4 more sources
Host Adaptive Evolution of Avian-Origin H3N2 Canine Influenza Virus [PDF]
Since its first isolation in around 2007, the avian-origin H3N2 canine influenza virus (CIV) has become established and continues to circulate in dog populations. This virus serves as a useful model for deciphering the complex evolutionary process of interspecies transmission of influenza A virus (IAV) from one species to its subsequent circulation in ...
Ayan Roy, Jinjin Yang, Zhipeng Zhang
exaly +6 more sources
The biological characteristics and infection dynamics of a novel H3N2 canine influenza virus genotype in beagles [PDF]
Background The canine influenza virus (CIV) outbreak has garnered considerable attention as it poses a significant threat to dog health. During the H3N2 CIV evolution in beagles, the virus formed a new clade after 2019 and gradually became more adaptable
Fei-fei Ge +6 more
doaj +4 more sources
Zoonotic Risk, Pathogenesis, and Transmission of Avian-Origin H3N2 Canine Influenza Virus [PDF]
ABSTRACT Two subtypes of influenza A virus (IAV), avian-origin canine influenza virus (CIV) H3N2 (CIV-H3N2) and equine-origin CIV H3N8 (CIV-H3N8), are enzootic in the canine population. Dogs have been demonstrated to seroconvert in response to diverse IAVs, and naturally occurring reassortants of CIV-H3N2 and the 2009 H1N1 ...
Hailiang Sun, Feng Wen, Larry A Hanson
exaly +5 more sources
Transmission and pathogenicity of canine H3N2 influenza virus in dog and guinea pig models
Background Influenza A virus causes respiratory disease in many animal species as well as in humans. Due to the high human-animal interface, the monitoring of canine influenza in dogs and the study of the transmission and pathogenicity of canine ...
Ratanaporn Tangwangvivat +9 more
doaj +3 more sources
Host-Adaptive Signatures of H3N2 Influenza Virus in Canine
Wild aquatic birds are the primary natural reservoir of influenza A viruses (IAVs), although a small number of viruses can spill over to mammals and circulate.
Xueyun Li +6 more
doaj +3 more sources
Spread of Canine Influenza A(H3N2) Virus, United States [PDF]
A canine influenza A(H3N2) virus emerged in the United States in February–March 2015, causing respiratory disease in dogs. The virus had previously been circulating among dogs in Asia, where it originated through the transfer of an avian-origin influenza
Ian E.H. Voorhees +12 more
doaj +3 more sources
Characterization of Canine Influenza Virus A (H3N2) Circulating in Dogs in China from 2016 to 2018 [PDF]
Avian H3N2 influenza virus follows cross-host transmission and has spread among dogs in Asia since 2005. After 2015–2016, a new H3N2 subtype canine influenza epidemic occurred in dogs in North America and Asia.
Yuanguo Li +21 more
doaj +3 more sources
Association between nasal shedding and fever that influenza A (H3N2) induces in dogs [PDF]
Background Avian origin canine influenza virus was reported in Korea. The dog to dog contact transmission of the avian origin canine influenza virus (CIV) H3N2 and CIV H3N8 was shown by experimental contact transmission.
Oh Jinsik +10 more
doaj +3 more sources
The PB2 I714S mutation influenced mammalian adaptation of the H3N2 canine influenza virus by interfering with nuclear import efficiency and RNP complex assembly [PDF]
Avian influenza viruses (AIVs) are the origin of multiple mammal influenza viruses. The genetic determinants of AIVs adapted to humans have been widely elucidated, however, the molecular mechanism of cross-species transmission and adaptation of AIVs to ...
Xueyun Li +8 more
doaj +2 more sources

