Cats are more susceptible to the prevalent H3 subtype influenza viruses than dogs [PDF]
Recent reports have highlighted the increasing frequency of influenza A virus (IAV) spillover events from other species to dogs and cats. IAV, particularly the H3 subtype, exhibits a broad host range and a propensity for interspecies transmission, as ...
Jie Deng +5 more
doaj +2 more sources
Negative regulation of reassortant canine influenza virus replication and key site identification in porcine and ferret bronchial epithelial cell lines [PDF]
The segmented nature and high mutability of the influenza virus RNA genome facilitate rapid mutation and reassortment, allowing the virus to breach host barriers and migrate between different species, potentially leading to unpredictable influenza ...
Jingjing Guo +13 more
doaj +2 more sources
Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants [PDF]
Background In 2007, the canine influenza H3N2 virus (H3N2-CIV) first emerged in the canine population in South Korea. The virus had since spread internationally and continues to circulate in the canines.
Tonia T. Kam +9 more
doaj +2 more sources
Canine Influenza Virus A(H3N2) Clade with Antigenic Variation, China, 2016–2017 [PDF]
During 2012–2017, we collected throat swabs from dogs in China to characterize canine influenza virus (CIV) A(H3N2) isolates. A new antigenically and genetically distinct CIV H3N2 clade possessing mutations associated with mammalian adaptation emerged in
Yanli Lyu +13 more
doaj +3 more sources
Intranasal NS1-truncated live attenuated canine influenza vaccine confers superior protection compared to inactivated vaccine in beagles [PDF]
Canine influenza virus (CIV) H3N2 continues to circulate among companion animals, posing a zoonotic risk due to its potential for cross-species transmission.
Jaehyun Hwang +15 more
doaj +2 more sources
The influenza B virus candidate vaccine expressing H3 hemagglutinin developed in suspension MDCK cells confers protection against lethal H3N2 avian influenza in BALB/c mice [PDF]
Influenza viruses cause annual seasonal epidemics and occasional pandemics. Vaccination is most effective at preventing influenza virus infections.
Yushu Wu +8 more
doaj +2 more sources
Genetic and evolutionary analysis of emerging H3N2 canine influenza virus. [PDF]
The H3N2 canine influenza virus (CIV) originated from an avian species. Since its emergence, it has circulated in multiple states and has caused pandemics among dog populations; however, no comprehensive studies have explored the causes driving these ongoing cases. The study of the codon usage patterns of viruses can reveal the genetic changes required
Li G +9 more
europepmc +4 more sources
H3N2 canine influenza virus and Enterococcus faecalis coinfection in dogs in China. [PDF]
In May 2017, 17 dogs in a German Shepherd breeding kennel in northern China developed respiratory clinical signs. The owner treated the dogs with an intravenous injection of Shuang-Huang-lian, a traditional Chinese medicine, and azithromycin. The respiratory signs improved 3 days post-treatment, however, cysts were observed in the necks of eight dogs ...
Zhou L +6 more
europepmc +5 more sources
The evolution and epidemiology of H3N2 canine influenza virus after 20 years in dogs. [PDF]
ABSTRACT The H3N2 canine influenza virus (CIV) emerged from an avian reservoir in Asia around 2004. As the virus has now been circulating entirely among dogs for 20 years, we here update our understanding of the evolution of virus in its new host.
Wasik BR +9 more
europepmc +3 more sources
Origins and Evolutionary Dynamics of H3N2 Canine Influenza Virus. [PDF]
ABSTRACT Influenza A viruses (IAVs) are maintained mainly in wild birds, and despite frequent spillover infections of avian IAVs into mammals, only a small number of viruses have become established in mammalian hosts. A new H3N2 canine influenza virus (CIV) of avian origin emerged in Asia in the mid-2000s and is now circulating in dog ...
Zhu H, Hughes J, Murcia PR.
europepmc +4 more sources

