The recent moratorium on research using engineered H5N1 influenza viruses is a move which cannot achieve its aims as it ignores the prevalence of molecular biology.
openaire +2 more sources
The history of the research with the highly pathogenic avian influenza virus H5N1 and the publication of the results of that research is reminiscent of the Buddhist “Parable of the Blind Men and the Elephant.” In the parable, the Buddha relates a story of a raja who, when confronted with disputatious scholars, gathered blind men and presented each man ...
openaire +3 more sources
A Single Immunization with Soluble Recombinant Trimeric Hemagglutinin Protects Chickens against Highly Pathogenic Avian Influenza Virus H5N1 [PDF]
Background: The highly pathogenic avian influenza (HPAI) virus H5N1 causes multi-organ disease and death in poultry, resulting in significant economic losses in the poultry industry.
Dep Infectieziekten Immunologie +17 more
core +3 more sources
Design, Synthesis and In Vivo Evaluation of a Candidate Fusion Epitopic Construct Vaccine Based on M2e, HA1, HA2, NA and NP Fragments of the Highly Pathogenic Avian H5N1 Influenza Virus [PDF]
The H5N1 subtype of Influenza virus, have a very high pathogenicity and lethality in humans and animals, and the need to develop new vaccines with a wide range of effects against this pathogen seems to be very crucial.
Adel Hamidi +2 more
doaj +1 more source
طورنا اختبارًا حساسًا وسريعًا في الوقت الفعلي للتفاعل المتسلسل للبوليميراز والنسخ العكسي (RT - PCR) للكشف عن فيروس الأنفلونزا A H5N1 في العينات السريرية. تم تقييم هذا الفحص باستخدام عينات من مرضى مصابين بفيروس H5N1 وأظهر حساسية أكبر ووقت دوران أسرع من RT - PCR المتداخلة.
Enders K. O. Ng +4 more
openaire +3 more sources
Changes in poultry handling behavior and poultry mortality reporting among rural Cambodians in areas affected by HPAI/H5N1. [PDF]
BACKGROUND: Since 2004, 21 highly pathogenic avian influenza H5N1 outbreaks in domestic poultry and eight human cases have been confirmed in Cambodia. As a result, a large number of avian influenza education campaigns have been ongoing in provinces in ...
Inst Pasteur +35 more
core +1 more source
Antigenic drift in H5N1 avian influenza virus in poultry is driven by mutations in major antigenic sites of the hemagglutinin molecule analogous to those for human influenza virus [PDF]
H5N1 highly pathogenic avian influenza virus has been endemic in poultry in Egypt since 2008, notwithstanding the implementation of mass vaccination and culling of infected birds.
Arafa, Abdel +19 more
core +1 more source
Marked Rise in Replikin Counts in H5N1 Influenza Virus Localized to Lethality Gene p B1. [PDF]
: Virus outbreaks have been found to be related to the concentration of a new class of genomic peptides, Replikins^1^. The eight genes of H5N1 influenza virus were analyzed for the distribution of Replikin Counts (number Replikins /100 amino acids) in 2 ...
Samuel Bogoch +2 more
core +1 more source
H5N1 outbreaks and enzootic influenza
Ongoing outbreaks of H5N1 avian influenza in migratory waterfowl, domestic poultry, and humans in Asia during the summer of 2005 present a continuing, protean pandemic threat. We review the zoonotic source of highly pathogenic H5N1 viruses and their genesis from their natural reservoirs. The acquisition of novel traits, including lethality to waterfowl,
Guan, Y, Webster, RG, Peiris, M, Chen, H
openaire +4 more sources
Since the first confirmed human infection with avian influenza A(H5N1) virus was reported in Hong Kong SAR (China) in 1997, sporadic zoonotic avian influenza viruses causing human illness have been identified globally with the World Health Organization ...
Sarah Hamid +10 more
doaj +1 more source

