Results 31 to 40 of about 15,735 (180)

H5N1 influenza and the implications for Europe [PDF]

BMJ, 2005
In the 20th century, the world experienced three influenza A pandemics: “Spanish flu” claiming 20-40 million lives in 1918-9 and the “Asian flu” of 1957 and “Hong Kong flu” of 1968, each of which claimed 1-4 million lives.1 It might be about to face another.
Denis, Coulombier, Karl, Ekdahl
openaire   +2 more sources

H5N1 Clade 2.2 Polymorphism Tracing Identifies Influenza Recombination and Potential Vaccine Targets [PDF]

, 2007
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1. The number of confirmed human cases now exceeds 300 and the associated Case Fatality Rate exceeds 60% 2.
Nasr M. ElSayed, A Nayei, A A. Abdelghani, Jeffery Tjaden, Mona Aly, Marshall Monteville, Hala Essmat, A Abdelghani, Bruce Boynton, A I. Nayei, Henry Niman, Moustafa Mansour, Kenneth Earhart, Henry L. Niman, Magdi Saad, Moustafa M. Mansour, Hala M. Essmat, Mona M. Aly, Nasr ElSayed, Magdi D. Saad, A-SA Arafa, Kenneth C. Earhart, Elassai Labib, Bruce R. Boynton, E Ayoub, Marshall R. Monteville, Elassai M. Labib   +26 more
core   +1 more source

Epizootic outbreak of influenza A / H5N1 among wild and farm birds in the vicinity of Komsomolsk‐on‐Amur in the autumn of 2022

Юг России: экология, развитие
Aim of the work was to investigate an epizootic outbreak in the vicinity of Komsomolsk‐on‐Amur (Khabarovsk Territory) in October 2022 among wild and agricultural birds.Material and methods included analysis of epizootic data, pathologic and anatomical ...
M. Yu. Shchelkanov, M. N. Dunaeva, A. A. Belik, M. V. Getke, A. B. Pott, I. S. Chalenko, O. V. Iunikhina, I. E. Dombrovskaya, D. V. Pankratov   +8 more
doaj   +1 more source

Multiplex real-time reverse transcription polymerase chain reaction for differential detection of H5, N1, and N8 genes of highly pathogenic avian influenza viruses

Veterinární Medicína, 2017
Rapid and differential diagnosis of highly pathogenic avian influenza virus (HPAIV) subtype H5 is essential for the effective prevention and control of outbreaks caused by this pathogen.
Y.R. Park, E.M. Kim, Y.J. Lee, S.G. Yeo, C.K. Park   +4 more
doaj   +1 more source

The H5N1 Moratorium Controversy and Debate [PDF]

mBio, 2012
The pause in gain-of-function experiments involving highly pathogenic avian influenza virus to dissect mechanisms of mammalian transmission and virulence is a historic moment for science. The scientific community and the greater society that it serves are currently engaged in a vigorous debate on whether and how to carry out experiments that could ...
Arturo Casadevall, Thomas Shenk
openaire   +3 more sources

A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles [PDF]

, 2012
© 2012 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Shui-Ling Chu, Béatrice Nal, Tang, D, Chi-Hong Lam, Yuen-Man Lam, Tang Dong-Jiang, Lam Chi-Hong, Lam Yuen-Man, Bruzzone Roberto, Peiris, JS, Buchy Philippe, Siu, YL, Dong-Jiang Tang, Chu Shui-Ling, Tang, DJ, Yu-Lam Siu, Nal, B, Peiris J. S. Malik, J S Malik Peiris, Peiris, J S Malik, Siu Yu-Lam, Bruzzone, R, Chu, SL, Lam, CH, Philippe Buchy, Buchy, Philippe, Tang, Dong-Jiang, Bruzzone, Roberto, Nal Béatrice, Lam, YM, Chu, Shui-Ling, Siu, Yu-Lam, Lam, Chi-Hong, Roberto Bruzzone, Peiris, JSM, Nai, B, Buchy, P, Nal, Béatrice, Lam, Yuen-Man   +38 more
core   +2 more sources

Randomized, double-blind, multi-center, phase III clinical trial to evaluate the immunogenicity and safety of MG1109 (egg-based pre-pandemic influenza A/H5N1 vaccine) in healthy adults

Human Vaccines & Immunotherapeutics, 2017
Considering the pandemic potential of avian influenza A/H5N1, development of an effective and well-tolerated vaccine is an essential part of pandemic preparedness plans.
Joon Young Song, Min Joo Choi, Ji Yun Noh, Won Suk Choi, Hee Jin Cheong, Seong-Heon Wie, Jin-Soo Lee, Gyu-Jin Woo, Sang Ho Lee, Woo Joo Kim   +9 more
doaj   +1 more source

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]

, 2011
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, Adolfo, García-Sastre, A., Rong Hai, Hale Benjamin G., Pena, Lindomar, Hai, Rong, John Steel, Manicassamy Balaji, Daniel R. Pérez, Pérez Daniel R., Manicassamy, Balaji, Pena, L., Benjamin G. Hale, Sutton, T., Zsuzsanna T Varga, Troy Sutton, Sutton Troy, Varga Zsuzsanna T., Hale, B.G., Varga, Zsuzsanna T, Pena Lindomar, Zsuzsanna T. Varga, Hale, Benjamin G, Balaji Manicassamy, Adolfo García-Sastre, Schmolke, M., Hai Rong, Hai, R., Daniel R Pérez, Pérez, D.R., Sutton, Troy, Steel, John, Pérez, Daniel R, Steel, J., Steel John, García-Sastre Adolfo, Manicassamy, B., Mirco Schmolke, Lindomar Pena, Benjamin G Hale, Schmolke, Mirco, Varga, Z.T., Schmolke Mirco   +42 more
core   +2 more sources

Purification and immunogenicity of hemagglutinin from highly pathogenic avian influenza virus H5N1 expressed in Nicotiana benthamiana

Human Vaccines & Immunotherapeutics, 2017
Highly pathogenic avian influenza (HPAI) H5N1 is an ongoing global health concern due to its severe sporadic outbreaks in Asia, Africa and Europe, which poses a potential pandemic threat.
Teen-Lee Pua, Xiao Ying Chan, Hwei-San Loh, Abdul Rahman Omar, Vidadi Yusibov, Konstantin Musiychuk, Alexandra C. Hall, Megan V. Coffin, Yoko Shoji, Jessica A. Chichester, Hong Bi, Stephen J. Streatfield   +11 more
doaj   +1 more source

Highly Pathogenic Avian Flu A(H5N1): State of Affairs in 2009–2012 and Forecast of Its Pandemic Potential

Проблемы особо опасных инфекций, 2013
Avian flu is an infectious viral disease in birds that still retains its positions in some parts of Asia and Africa. This review contains summarization and analysis of facts regarding the current situation on highly pathogenic avian flu A-type subtype ...
A. M. Shestopalov, N. V. Kikhtenko, A. N. Sergeev, V. N. Mikheev, T. N. Il’Icheva, A. B. Ryzhikov   +5 more
doaj   +1 more source