Results 31 to 40 of about 68,044 (228)

Randomized, double-blind, multi-center, phase III clinical trial to evaluate the immunogenicity and safety of MG1109 (egg-based pre-pandemic influenza A/H5N1 vaccine) in healthy adults

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Considering the pandemic potential of avian influenza A/H5N1, development of an effective and well-tolerated vaccine is an essential part of pandemic preparedness plans.
Joon Young Song   +9 more
doaj   +1 more source

Modeling highly pathogenic avian influenza transmission in wild birds and poultry in West Bengal, India. [PDF]

open access: yes, 2013
Wild birds are suspected to have played a role in highly pathogenic avian influenza (HPAI) H5N1 outbreaks in West Bengal. Cluster analysis showed that H5N1 was introduced in West Bengal at least 3 times between 2008 and 2010.
Aly, Sharif S   +3 more
core   +1 more source

Purification and immunogenicity of hemagglutinin from highly pathogenic avian influenza virus H5N1 expressed in Nicotiana benthamiana

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Highly pathogenic avian influenza (HPAI) H5N1 is an ongoing global health concern due to its severe sporadic outbreaks in Asia, Africa and Europe, which poses a potential pandemic threat.
Teen-Lee Pua   +11 more
doaj   +1 more source

H5N1: A Cautionary Tale [PDF]

open access: yesFrontiers in Public Health, 2014
The history of the research with the highly pathogenic avian influenza virus H5N1 and the publication of the results of that research is reminiscent of the Buddhist “Parable of the Blind Men and the Elephant.” In the parable, the Buddha relates a story of a raja who, when confronted with disputatious scholars, gathered blind men and presented each man ...
openaire   +3 more sources

Bogoch Replikins Pandemic Prevention: Increase of Strain-Specific Influenza Genomic Replikin Counts, Having Predicted Outbreaks and their Location Seven Times Consecutively, Up to Two Years in Advance, Provides Time for Prevention of Pandemics [PDF]

open access: yes, 2012
Earlier studies have shown that the increased concentration of a new class of virus genomic peptides, Replikins, precedes and predicts virus outbreaks. We now find that the area in the genome of the highest concentration of Replikins, and the country in ...
Elenore S. Bogoch, Samuel Bogoch
core   +2 more sources

analysis of antiviral immune response against avian influenza virus in chicken tracheal epithelial cells [PDF]

open access: yesAnimal Bioscience
Objective Avian influenza virus (AIV) infections first affect the respiratory tract of chickens. The epithelial cells activate the host immune system, which leads to the induction of immune-related genes and the production of antiviral molecules against ...
Jubi Heo   +4 more
doaj   +1 more source

Marked Rise in Replikin Counts in H5N1 Influenza Virus Localized to Lethality Gene p B1. [PDF]

open access: yes, 2011
: Virus outbreaks have been found to be related to the concentration of a new class of genomic peptides, Replikins^1^. The eight genes of H5N1 influenza virus were analyzed for the distribution of Replikin Counts (number Replikins /100 amino acids) in 2 ...
Elenore S. Bogoch, Samuel Bogoch
core   +2 more sources

Highly Pathogenic Avian Flu A(H5N1): State of Affairs in 2009–2012 and Forecast of Its Pandemic Potential

open access: yesПроблемы особо опасных инфекций, 2013
Avian flu is an infectious viral disease in birds that still retains its positions in some parts of Asia and Africa. This review contains summarization and analysis of facts regarding the current situation on highly pathogenic avian flu A-type subtype ...
A. M. Shestopalov   +5 more
doaj   +1 more source

A comparison of clinical and epidemiological characteristics of fatal human infections with H5N1 and human influenza viruses in Thailand, 2004-2006. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: The National Avian Influenza Surveillance (NAIS) system detected human H5N1 cases in Thailand from 2004-2006. Using NAIS data, we identified risk factors for death among H5N1 cases and described differences between H5N1 and human (seasonal ...
Vivek Shinde   +8 more
doaj   +1 more source

H5N1 outbreaks and enzootic influenza

open access: yesBiodiversity, 2006
Ongoing outbreaks of H5N1 avian influenza in migratory waterfowl, domestic poultry, and humans in Asia during the summer of 2005 present a continuing, protean pandemic threat. We review the zoonotic source of highly pathogenic H5N1 viruses and their genesis from their natural reservoirs. The acquisition of novel traits, including lethality to waterfowl,
Guan, Y, Webster, RG, Peiris, M, Chen, H
openaire   +4 more sources

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