Concurrent Acquisition of a Single Nucleotide Polymorphism in Diverse Influenza H5N1 Clade 2.2 Sub-clades [PDF]
, 2008 Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1,2. The number of confirmed human cases now exceeds 300 and the associated Case Fatality Rate exceeds 60% 3.
Hala M. Esmat +10 more
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Pathobiology of avian influenza in wild bird species [PDF]
, 2012 Avian influenza viruses, especially highly pathogenic avian influenza viruses (HPAIV), affect a wide range of species, including humans and have thus become a major concern for veterinary medicine and public health.
Bröjer, Caroline
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Molecular surveillance confirms absence of avian influenza virus type A in Ecuadorian poultry: A retrospective reverse transcription quantitative polymerase chain reaction study from April 2023 to June 2024 [PDF]
Veterinary WorldBackground and Aim: Avian influenza (AI) is a highly contagious zoonotic disease affecting birds and, occasionally, humans. Ecuador confirmed its first case of AI in late 2022, resulting in significant avian mortality and economic losses.
Byron Puga-Torres +2 more
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Heterosubtype neutralizing responses to influenza A (H5N1) viruses are mediated by antibodies to virus haemagglutinin. [PDF]
PLoS ONE, 2009 BACKGROUND:It is increasingly clear that influenza A infection induces cross-subtype neutralizing antibodies that may potentially confer protection against zoonotic infections. It is unclear whether this is mediated by antibodies to the neuraminidase (NA)
Jean-Michel Garcia +7 more
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Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders
Advanced Science, Volume 13, Issue 50, 7 September 2026.Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley +1 more source
Bogoch Replikins Pandemic Prevention: Increase of Strain-Specific Influenza Genomic Replikin Counts, Having Predicted Outbreaks and their Location Seven Times Consecutively, Up to Two Years in Advance, Provides Time for Prevention of Pandemics [PDF]
, 2012 Earlier studies have shown that the increased concentration of a new class of virus genomic peptides, Replikins, precedes and predicts virus outbreaks. We now find that the area in the genome of the highest concentration of Replikins, and the country in ...
Samuel Bogoch, Elenore S. Bogoch
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Tsinghua Science and Technology, 2015 Highly Pathogenic Avian Influenza (HPAI) H5N1 has attracted much attention as a potential pandemic virus in humans, which makes death inevitable in humans. Neuraminidase (NA) has an important role in viral replication.
Usman Sumo Friend Tambunan +3 more
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High‐Content CRISPR Screening: Methods and Applications
MedComm, Volume 7, Issue 9, September 2026.High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang +6 more
wiley +1 more source
Chemical & Engineering News Archive, 2012 If William Shakespeare had never lived, the plays he wrote would not exist. Someone might have written: To be or not to be, that is the question: But it most certainly would not have been followed with: Whether ’tis Nobler in the mind to suffer The Slings and Arrows of outrageous Fortune Or to take Arms against a Sea of troubles And by opposing end ...
openaire +1 more source
Ветеринария сегодня, 2018 Data on examination of chickens intranasally infected with А/duck/Altai/469/14 H5N1 isolate of avian influenza virus for clinical signs and microscopic and gross pathomorphological lesions in their organs are given in the paper.
V. Yu. Sosipatorova +3 more
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