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The Next Disease X‐ H5N6 Avian Influenza's Evolving Threat to Human Health and Chances of Future Global Outbreak: A Narrative Review [PDF]

open access: yesHealth Science Reports
Background and Aims H5N6 avian influenza has been a concern that can initiate the next global pandemic (called Disease X). Most infections have been among those in Asia, especially China, since the 2014 first human case.
Shoubeho Sadique Shandhi   +3 more
doaj   +4 more sources

Phylogenetic and Phylogeographic Analysis of the Highly Pathogenic H5N6 Avian Influenza Virus in China

open access: yesViruses, 2022
The clade 2.3.4.4b H5N8 avian influenza viruses (AIVs) have caused the loss of more than 33 million domestic poultry worldwide since January 2020. Novel H5N6 reassortants with hemagglutinin (HA) from clade 2.3.4.4b H5N8 AIVs are responsible for multiple ...
Hanlin Liu, Ming Liao, Hailiang Sun
exaly   +6 more sources

H5N6 influenza virus infection, the newest influenza

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2015
The most recent new emerging infection is the H5N6 influenza virus infection. This infection has just been reported from China in early May 2014. The disease is believed to be a cross species infection. All indexed cases are from China.
Beuy Joob
exaly   +5 more sources

Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective study [PDF]

open access: yesFrontiers in Public Health
ObjectiveThe objective is to examine the epidemiology and clinical features of human cases infected with H5N6 avian influenza in Sichuan Province from 2014 to 2024, and to offer guidance for the prevention and management of human infections with H5N6 ...
Lijun Zhou   +17 more
doaj   +5 more sources

Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice [PDF]

open access: yesFrontiers in Microbiology, 2017
At least 15 cases of human beings infected with H5N6 have been reported since 2014, of which at least nine were fatal. The highly pathogenic avian H5N6 influenza virus may pose a serious threat to both public health and the poultry industry. However, the
Chunmao Zhang, Zhongyi Wang, Min Zhi
exaly   +6 more sources

Novel Reassortant Avian Influenza A(H5N6) Virus, China, 2021

open access: yesEmerging Infectious Diseases, 2022
Although reports of human infection with influenza A(H5N6) increased in 2021, reports of similar H5N6 virus infection in poultry are few. We detected 10 avian influenza A(H5N6) clade 2.3.4.4b viruses in poultry from 4 provinces in China.
Junhong Chen   +13 more
doaj   +4 more sources

Risk distribution of human infections with avian influenza A (H5N1, H5N6, H9N2 and H7N9) viruses in China [PDF]

open access: yesFrontiers in Public Health
BackgroundThis study aimed to investigate epidemiologic characteristics of major human infection with avian influenza and explore the factors underlying the spatial distributions, particularly H5N6 and H9N2, as H9N2 could directly infect mankind and ...
Rongrong Qu   +9 more
doaj   +5 more sources

The complexity of human infected AIV H5N6 isolated from China [PDF]

open access: yesBMC Infectious Diseases, 2016
Background Novel avian influenza viruses (AIVs) of H7N9, H10N8, and H5N6 are currently circulating in China’s poultry flocks, occasionally infecting human and other mammals.
Zhijie Zhang   +6 more
doaj   +5 more sources

Continuous Reassortment of Clade 2.3.4.4 H5N6 Highly Pathogenetic Avian Influenza Viruses Demonstrating High Risk to Public Health

open access: yesPathogens, 2020
Since it firstly emerged in China in 2013, clade 2.3.4.4 H5N6 highly pathogenic avian influenza viruses (HPAIVs) has rapidly replaced predominant H5N1 to become the dominant H5 subtype in China, especially in ducks.
Huanan Li, Qian Li, Jiahao Zhang
exaly   +4 more sources

Emergence and Genetic Characteristics of H5N1, H5N6, and H5N3 Clade 2.3.4.4b High Pathogenicity Avian Influenza Viruses in South Korea During the 2023-2024 and 2024-2025 Winter Seasons. [PDF]

open access: yesTransbound Emerg Dis
Since 2020, clade 2.3.4.4b H5Nx high pathogenicity avian influenza viruses (HPAIVs) have consistently spread across continents, causing outbreaks worldwide.
Cha RM   +10 more
europepmc   +3 more sources

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