Results 31 to 40 of about 3,454 (171)

Exploring the global immune landscape of peripheral blood mononuclear cells in H5N6-infected patient with single-cell transcriptomics

BMC Medical Genomics, 2023
Background Avian influenza viruses (AIV), particularly H5N6, have risen in infection frequency, prompting major concerns. Single-cell RNA sequencing (scRNA-seq) can illustrate the immune cell landscape present in the peripheral circulation of influenza ...
Jiamin Gao, Jing Wei, Simei Qin, Sheng Liu, Shuangyan Mo, Qian Long, Shiji Tan, Ning Lu, Zhouhua Xie, Jianyan Lin   +9 more
doaj   +1 more source

Amino Acid Substitutions Associated with Avian H5N6 Influenza A Virus Adaptation to Mice

Frontiers in Microbiology, 2017
At least 15 cases of human beings infected with H5N6 have been reported since 2014, of which at least nine were fatal. The highly pathogenic avian H5N6 influenza virus may pose a serious threat to both public health and the poultry industry. However, the
Chunmao Zhang, Zongzheng Zhao, Zhendong Guo, Jiajie Zhang, Jiaming Li, Yifei Yang, Shaoxia Lu, Zhongyi Wang, Min Zhi, Yingying Fu, Xiaoyu Yang, Lina Liu, Yi Zhang, Yuping Hua, Linna Liu, Hongliang Chai, Jun Qian   +16 more
doaj   +1 more source

Epidemiologic, Clinical, and Genetic Characteristics of Human Infections with Influenza A(H5N6) Viruses, China

Emerging Infectious Diseases, 2022
The recent rise in the frequency of influenza A(H5N6) infections in China has raised serious concerns about whether the risk for human infection has increased.
Wenfei Zhu, Xiyan Li, Jie Dong, Hong Bo, Jia Liu, Jiaying Yang, Ye Zhang, Hejiang Wei, Weijuan Huang, Xiang Zhao, Tao Chen, Jing Yang, Zi Li, Xiaoxu Zeng, Chao Li, Jing Tang, Li Xin, Rongbao Gao, Liqi Liu, Min Tan, Yuelong Shu, Lei Yang, Dayan Wang   +22 more
doaj   +1 more source

Serosurveillance of avian influenza A/H5N6 virus infection in poultry farmers, Gyeonggi Province, Republic of Korea, 2016–2017

International Journal of Infectious Diseases, 2018
Objectives: Between November 20, 2016 and April 17, 2017, outbreaks of highly pathogenic avian influenza (HPAI) A/H5N6 occurred on poultry farms in Gyeonggi Province in the Republic of Korea.
Sukhyun Ryu, Chi-Kyeong Kim, Kisoon Kim, Sang Hee Woo, Byung Chul Chun   +4 more
doaj   +1 more source

Nomenclature updates resulting from the evolution of avian influenza A(H5) virus clades 2.1.3.2a, 2.2.1, and 2.3.4 during 2013-2014. [PDF]

, 2015
AIM: The A/goose/Guangdong/1/96-like hemagglutinin (HA) genes of highly pathogenic avian influenza (HPAI) A(H5) viruses have continued to rapidly evolve since the most recent update to the H5 clade nomenclature by the WHO/OIE/FAO H5N1 Evolution Working ...
Donis, Ruben O, Smith, Gavin JD, World Health Organization/World Organisation for Animal Health/Food and Agriculture Organization (WHO/OIE/FAO) H5 Evolution Working Group   +2 more
core   +2 more sources

Viral factors in influenza pandemic risk assessment [PDF]

, 2016
The threat of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tiny fraction of which spark sustained transmission in humans.
Barclay, Wendy, Beauchemin, Catherine A.A., Bedford, Trevor, Belser, Jessica A., Cobey, Sarah, Friedrich, Thomas C., Handel, Andreas, Herfst, Sander, Kasson, Peter M., Lipsitch, Marc, Lloyd-Smith, James O., Maurer-Stroh, Sebastian, Murcia, Pablo R., Raman, Rahul, Riley, Steven, Roche, Benjamin, Russell, Charles J., Russell, Colin A., Wilke, Claus O.   +18 more
core   +4 more sources

Continuing Reassortant of H5N6 Subtype Highly Pathogenic Avian Influenza Virus in Guangdong

Frontiers in Microbiology, 2016
First identified in May 2014 in China’s Sichuan Province, initial cases of H5N6 avian influenza virus (AIV) infection in humans raised great concerns about the virus’s prevalence, origin, and development.
Runyu eYuan, Runyu eYuan, Zheng eWang, Yinfeng eKang, Jie eWu, Lirong eZou, Lijun eLiang, Xin eZhang, Yingchao eSong, Hanzhong eNi, Jinyan eLin, Changwen eKe   +11 more
doaj   +1 more source

Trade patterns facilitating highly pathogenic avian influenza virus dissemination in the free-grazing layer duck system in Vietnam [PDF]

, 2018
Highly pathogenic avian influenza (HPAI) viruses continue to threaten smallholder poultry producers in several South‐east Asian countries, including Vietnam.
Amonsin, Beaudoin, Braun, Bui, Cha, Chen, FAO, Fournié, Gilbert, Henning, Hulse-Post, Indriani, Kaplinsky, Le, McLeod, Meyer, Minh, Negovetich, Nguyen, Nguyen, Paul, R Core Team, Reardon, Rich, Rushton, Songserm, Sturm-Ramirez, Swayne, Tai, Tian, Van Kerkhove   +30 more
core   +4 more sources

Isolation of H5N6, H7N9 and H9N2 avian influenza A viruses from air sampled at live poultry markets in China, 2014 and 2015 [PDF]

, 2016
Zoonotic infections by avian influenza viruses occur at the human-poultry interface, but the modes of transmission have not been fully investigated. We assessed the potential for airborne and fomite transmission at live poultry markets in Guangzhou city ...
Cowling, BJ, GOPINATH, D, Huang, G, Kang, M, Ke, C, Lin, J, Lindsley, WG, Peiris, JSM, Song, Y, Wu, J, Yen, H, Zeng, X, Zhang, X, ZHOU, J, Zou, L   +14 more
core   +1 more source

N-linked glycosylation at site 158 of the HA protein of H5N6 highly pathogenic avian influenza virus is important for viral biological properties and host immune responses

Veterinary Research, 2021
Since 2014, clade 2.3.4.4 has become the dominant epidemic branch of the Asian lineage H5 subtype highly pathogenic avian influenza virus (HPAIV) in southern and eastern China, while the H5N6 subtype is the most prevalent. We have shown earlier that lack
Ruyi Gao, Min Gu, Liwei Shi, Kaituo Liu, Xiuli Li, Xiaoquan Wang, Jiao Hu, Xiaowen Liu, Shunlin Hu, Sujuan Chen, Daxin Peng, Xinan Jiao, Xiufan Liu   +12 more
doaj   +1 more source