Results 31 to 40 of about 3,103 (197)

Evaluation of Efficacy of Oil Adjuvanted H5N6 Inactivated Vaccine against Highly Pathogenic H5N6 and H5N1 Influenza Viruses Infected Chickens

Frontiers in Bioscience-Landmark, 2022
Background: Over the last 20 years, circulating highly pathogenic (HP) Asian H5 subtype avian influenza viruses have caused global pandemics in poultry and sporadic infections in humans.
Kuruppu Arachchillage Praboda Priyangi Kuruppuarachchi, Yunyueng Jang, Sang Heui Seo   +2 more
doaj   +3 more sources

Transmission Dynamics of Highly Pathogenic Avian Influenza A(H5N1) and A(H5N6) Viruses in Wild Birds, South Korea, 2023-2024. [PDF]

Emerg Infect Dis
We analyzed 15 cases of highly pathogenic avian influenza (HPAI) clade 2.3.4.4b virus infections detected in wild birds in South Korea during September 2023–March 2024. We isolated and sequenced 8 H5N1 and 7 H5N6 viruses.
Seo YR, Cho AY, Kim DJ, Si YJ, Jeong HS, Lee SW, Song CS, Lee DH.   +7 more
europepmc   +2 more sources

Investigation of Avian Influenza H5N6 Virus-like Particles as a Broad-Spectrum Vaccine Candidate against H5Nx Viruses

Viruses, 2022
Highly pathogenic avian influenza (HPAI) clade 2.3.4.4 viruses have been reported to be the source of infections in several outbreaks in the past decades.
Yu-Hsuan Yang, Ching-Hui Tai, Dayna Cheng, Ya-Fang Wang, Jen-Ren Wang   +4 more
doaj   +3 more sources

Diversity of avian influenza A(H5N6) viruses in wild birds in southern China [PDF]

Journal of General Virology, 2020
The predominance of H5N6 in ducks and continuous human cases have heightened its potential threat to public health in China. Therefore, the detection of emerging variants of H5N6 avian influenza viruses has become a priority for pandemic preparedness. Questions remain as to its origin and circulation within the wild bird reservoir and interactions at ...
Tao Zhang, Kai Fan, Xue Zhang, Yujuan Xu, Jian Xu, Bing Xu, Ruiyun Li   +6 more
openaire   +5 more sources

Comparison of Gross Lesions in Poultry Naturally Infected With High Pathogenicity Avian Influenza H5N6 and H5N1 Viruses in South Korea, 2023-2025. [PDF]

Transbound Emerg Dis
High pathogenicity avian influenza (HPAI) is an acute infectious disease of poultry and wild birds that has been occurring worldwide and has been controlled in many countries by culling birds on farms with disease outbreaks. We compared the gross lesions
Kim HR, Lee KN, Lee YJ, Her M.
europepmc   +2 more sources

Risk Assessment for Highly Pathogenic Avian Influenza A(H5N6/H5N8) Clade 2.3.4.4 Viruses [PDF]

Emerging Infectious Diseases, 2021
The numerous global outbreaks and continuous reassortments of highly pathogenic avian influenza (HPAI) A(H5N6/H5N8) clade 2.3.4.4 viruses in birds pose a major risk to the public health.
Christine H.T. Bui, Denise I.T. Kuok, Hin Wo Yeung, Ka-Chun Ng, Daniel K.W. Chu, Richard J. Webby, John M. Nicholls, J.S. Malik Peiris, Kenrie P.Y. Hui, Michael C.W. Chan   +9 more
doaj   +2 more sources

Characterization of novel highly pathogenic avian influenza A(H5N6) clade 2.3.4.4b virus in wild birds, East China, 2024. [PDF]

Virol Sin
Highlights • We reported a novel H5N6 HPAIV belonging to clade 2.3.4.4b in wild birds in eastern China.• The novel H5N6 HPAIV most likely descended from clade 2.3.4.4b H5N1 virus in Japan.• The novel H5N6 HPAIV evolved from reassortment with H5 HPAIVs ...
Sun R, Feng X, Huang J, Zheng F, Xie R, Zhang C, Zhang H, Xue Y, Liu A, Huang X, Yuan L, Zhao L.   +11 more
europepmc   +2 more sources

A Rapid Review Contrasting the Evidence on Avian Influenza A(H5Nx) Clades 2.3.4.4b and 2.3.2.1c in Humans. [PDF]

Zoonoses Public Health
ABSTRACT Avian influenza viruses (AIV) circulate in wild and domestic bird populations, posing an on‐going risk for zoonotic transmission and virus adaptation to mammals and humans. The A(H5Nx) clades 2.3.2.1c and 2.3.4.4b currently circulating have caused sporadic infections in humans.
Corrin T, Young KM, Qamar M, Pussegoda K, Baumeister A, Atchessi N, Leonard E, Waddell LA.   +7 more
europepmc   +2 more sources

N-linked glycosylation enhances hemagglutinin stability in avian H5N6 influenza virus to promote adaptation in mammals

PNAS Nexus, 2022
Clade 2.3.4.4 avian H5Ny viruses, namely H5N2, H5N6, and H5N8, have exhibited unprecedented intercontinental spread in poultry. Among them, only H5N6 viruses are frequently reported to infect mammals and cause serious human infections. In this study, the
Honglei Sun, G. Deng, Haoran Sun, Jingwei Song, Wei Zhang, Han Li, Xiaohui Wei, Fangtao Li, Xin Zhang, Jiyu Liu, Juan Pu, Yipeng Sun, Qi Tong, Y. Bi, Yufeng Xie, J. Qi, Kin-Chow Chang, G. Gao, Jinhua Liu   +18 more
semanticscholar   +3 more sources

Exploring the global immune landscape of peripheral blood mononuclear cells in H5N6-infected patient with single-cell transcriptomics

BMC Medical Genomics, 2023
Background Avian influenza viruses (AIV), particularly H5N6, have risen in infection frequency, prompting major concerns. Single-cell RNA sequencing (scRNA-seq) can illustrate the immune cell landscape present in the peripheral circulation of influenza ...
Jiamin Gao, Jing Wei, Simei Qin, Sheng Liu, Shuangyan Mo, Qian Long, Shiji Tan, Ning Lu, Zhouhua Xie, Jianyan Lin   +9 more
doaj   +2 more sources