Results 1 to 10 of about 2,355 (182)

Diverse infectivity, transmissibility, and pathobiology of clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses in chickens [PDF]

Emerging Microbes and Infections, 2023
Clade 2.3.4.4 Eurasian lineage H5Nx highly pathogenic avian influenza virus (HPAIV) has become the globally dominant clade and caused global outbreaks since 2014. The clade 2.3.4.4 viruses have evolved into eight hemagglutinin subgroups (2.3.4.4a-h).
Jung-Hoon Kwon, Kateri Bertran, Dong-Hun Lee, Miria Ferreira Criado, Lindsay Killmaster, Mary J. Pantin-Jackwood, David E. Swayne   +6 more
doaj   +5 more sources

Risk Assessment for Highly Pathogenic Avian Influenza A(H5N6/H5N8) Clade 2.3.4.4 Viruses. [PDF]

Emerg Infect Dis, 2021
The numerous global outbreaks and continuous reassortments of highly pathogenic avian influenza (HPAI) A(H5N6/H5N8) clade 2.3.4.4 viruses in birds pose a major risk to the public health.
Bui CHT, Kuok DIT, Yeung HW, Ng KC, Chu DKW, Webby RJ, Nicholls JM, Peiris JSM, Hui KPY, Chan MCW.   +9 more
europepmc   +7 more sources

Pandemic potential of highly pathogenic avian influenza clade 2.3.4.4 A(H5) viruses. [PDF]

Rev Med Virol, 2020
The panzootic caused by A/goose/Guangdong/1/96-lineage highly pathogenic avian influenza (HPAI) A(H5) viruses has occurred in multiple waves since 1996.
Yamaji R, Saad MD, Davis CT, Swayne DE, Wang D, Wong FYK, McCauley JW, Peiris JSM, Webby RJ, Fouchier RAM, Kawaoka Y, Zhang W.   +11 more
europepmc   +6 more sources

Assessment of Survival Kinetics for Emergent Highly Pathogenic Clade 2.3.4.4 H5Nx Avian Influenza Viruses [PDF]

Viruses
High pathogenicity avian influenza viruses (HPAIVs) cause high morbidity and mortality in poultry species. HPAIV prevalence means high numbers of infected wild birds could lead to spill over events for farmed poultry.
Caroline J. Warren, Sharon M. Brookes, Mark E. Arnold, Richard M. Irvine, Rowena D. E. Hansen, Ian H. Brown, Ashley C. Banyard, Marek J. Slomka   +7 more
doaj   +4 more sources

A broad-spectrum vaccine candidate against H5 viruses bearing different sub-clade 2.3.4.4 HA genes [PDF]

npj Vaccines
The global spread of H5 clade 2.3.4.4 highly pathogenic avian influenza (HPAI) viruses threatens poultry and public health. The continuous circulation of these viruses has led to their considerable genetic and antigenic evolution, resulting in the ...
Yuancheng Zhang, Pengfei Cui, Jianzhong Shi, Xianying Zeng, Yongping Jiang, Yuan Chen, Jie Zhang, Congcong Wang, Yan Wang, Guobin Tian, Hualan Chen, Huihui Kong, Guohua Deng   +12 more
doaj   +4 more sources

Continuous Reassortment of Clade 2.3.4.4 H5N6 Highly Pathogenetic Avian Influenza Viruses Demonstrating High Risk to Public Health [PDF]

Pathogens, 2020
Since it firstly emerged in China in 2013, clade 2.3.4.4 H5N6 highly pathogenic avian influenza viruses (HPAIVs) has rapidly replaced predominant H5N1 to become the dominant H5 subtype in China, especially in ducks.
Huanan Li, Qian Li, Bo Li, Yang Guo, Jinchao Xing, Qiang Xu, Lele Liu, Jiahao Zhang, Wenbao Qi, Weixin Jia, Ming Liao   +10 more
doaj   +5 more sources

Highly Pathogenic Avian Influenza Clade 2.3.4.4 Subtype H5N6 Viruses Isolated from Wild Whooper Swans, Mongolia, 2020 [PDF]

Emerging Infectious Diseases, 2021
We identified clade 2.3.4.4 highly pathogenic avian influenza A(H5N6) viruses from whooper swans (Cygnus cygnus) found dead in Mongolia. The identification of these infections in wild birds in this area is of concern because of the potential for virus ...
Sol Jeong, Nyamsuren Otgontogtokh, Dong-Hun Lee, Bayarmagnai Davganyam, Sun-Hak Lee, Andrew Y. Cho, Erdene-Ochir Tseren-Ochir, Chang-Seon Song   +7 more
doaj   +5 more sources

Key Amino Acid Residues That Determine the Antigenic Properties of Highly Pathogenic H5 Influenza Viruses Bearing the Clade 2.3.4.4 Hemagglutinin Gene [PDF]

Viruses, 2023
The H5 subtype highly pathogenic avian influenza viruses bearing the clade 2.3.4.4 HA gene have been pervasive among domestic poultry and wild birds worldwide since 2014, presenting substantial risks to human and animal health.
Yuancheng Zhang, Pengfei Cui, Jianzhong Shi, Yuan Chen, Xianying Zeng, Yongping Jiang, Guobin Tian, Chengjun Li, Hualan Chen, Huihui Kong, Guohua Deng   +10 more
doaj   +2 more sources

Subclinical Infection and Transmission of Clade 2.3.4.4 H5N6 Highly Pathogenic Avian Influenza Virus in Mandarin Duck (Aix galericulata) and Domestic Pigeon (Columbia livia domestica) [PDF]

Viruses, 2021
Since 2014, H5Nx clade 2.3.4.4 highly pathogenic avian influenza viruses (HPAIV) have caused outbreaks in wild birds and poultry in multiple continents, including Asia, Europe, Africa, and North America. Wild birds were suspected to be the sources of the
Sol Jeong, Jung-Hoon Kwon, Sun-Hak Lee, Yu-Jin Kim, Jei-Hyun Jeong, Jung-Eun Park, Weon-Hwa Jheong, Dong-Hun Lee, Chang-Seon Song   +8 more
doaj   +2 more sources

Human Clade 2.3.4.4 A/H5N6 Influenza Virus Lacks Mammalian Adaptation Markers and Does Not Transmit via the Airborne Route between Ferrets [PDF]

mSphere, 2018
Since their emergence in 1997, A/H5N1 influenza viruses of the A/goose/Guangdong/1/96 lineage have diversified in multiple genetic and antigenic clades upon continued circulation in poultry in several countries in Eurasia and Africa.
Sander Herfst, Chris K. P. Mok, Judith M. A. van den Brand, Stefan van der Vliet, Miruna E. Rosu, Monique I. Spronken, Zifeng Yang, Dennis de Meulder, Pascal Lexmond, Theo M. Bestebroer, J. S. Malik Peiris, Ron A. M. Fouchier, Mathilde Richard   +12 more
doaj   +3 more sources