Reassortant Highly Pathogenic Influenza A(H5N6) Virus in Laos
In March 2014, avian influenza in poultry in Laos was caused by an emergent influenza A(H5N6) virus. Genetic analysis indicated that the virus had originated from reassortment of influenza A(H5N1) clade 2.3.2.1b, variant clade 2.3.4, and influenza A(H6N6) viruses that circulate broadly in duck populations in southern and eastern China.
Frank Y.K. Wong +17 more
openaire +4 more sources
Characterization of Highly Pathogenic Avian Influenza Virus A(H5N6), Japan, November 2016 [PDF]
Highly pathogenic avian influenza viruses (HPAIVs) A(H5N6) were concurrently introduced into several distant regions of Japan in November 2016. These viruses were classified into the genetic clade 2.3.4.4c and were genetically closely related to H5N6 HPAIVs recently isolated in South Korea and China.
Okamatsu, Masatoshi +19 more
openaire +6 more sources
A human monoclonal antibody targeting the monomeric N6 neuraminidase confers protection against avian H5N6 influenza virus infection. [PDF]
The influenza neuraminidase (NA) is a potential target for the development of a next-generation influenza vaccine, but its antigenicity is not well understood.
Wang M +9 more
europepmc +2 more sources
Immune Responses of Chickens Infected with Wild Bird-Origin H5N6 Avian Influenza Virus [PDF]
Since April 2014, new infections of H5N6 avian influenza virus (AIV) in humans and domestic poultry have caused considerable economic losses in the poultry industry and posed an enormous threat to human health worldwide.
Shimin Gao +13 more
doaj +2 more sources
Emergence of HPAI H5N6 Clade 2.3.4.4b in Wild Birds: A Case Study From South Korea, 2023. [PDF]
The emergence and evolution of avian influenza A viruses (AIVs) pose significant challenges to both public health and animal husbandry worldwide. Here, we characterized a novel reassortant highly pathogenic avian influenza virus (HPAIV), clade 2.3.4.4b ...
Jeong CG +12 more
europepmc +2 more sources
Highly pathogenic avian influenza viruses (HPAIV), such as H5N1, H5N6, and H7N9, have been reported to frequently infect humans, but acute encephalitis caused by HPAIV in humans has been rarely reported.
Libing Zhang +13 more
exaly +2 more sources
Objectives: Between November 20, 2016 and April 17, 2017, outbreaks of highly pathogenic avian influenza (HPAI) A/H5N6 occurred on poultry farms in Gyeonggi Province in the Republic of Korea.
Sukhyun Ryu +4 more
doaj +2 more sources
Genetic diversity of highly pathogenic avian influenza H5N6 and H5N8 viruses in poultry markets in Guangdong, China, 2020-2022. [PDF]
H5 highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/96 (Gs/Gd) lineage continue to evolve and cause outbreaks in domestic poultry and wild birds, with sporadic spillover infections in mammals.
Yang K +10 more
europepmc +2 more sources
P-1476. Safety of Homologous or Heterologous Priming and Booster Vaccinations with H5N8 or H5N6 MF59-Adjuvanted Cell Culture-derived Influenza Vaccine in Healthy Subjects ≥18 Years of Age [PDF]
Background Avian influenza is a global threat. This study assessed safety of a homologous and heterologous prime-boost regimen with MF59 adjuvanted, cell culture-derived H5N8 or H5N6 influenza vaccine (aH5N8c, aH5N6c) in adults aged ≥18 years. Methods In
A. Brosz +4 more
europepmc +2 more sources
The Novel 2.3.4.4b H5N6 Highly Pathogenic Avian Influenza Viruses Isolated From Wild Birds in 2023 Posing a Potential Risk to Human Health. [PDF]
The highly pathogenic avian influenza 2.3.4.4b H5 viruses have been a cause for concern recently, as they have been responsible for continuous outbreaks since 2021. In China, the H5N6 subtype has been predominantly circulating in domestic poultry but has
Xu Y +7 more
europepmc +2 more sources

