Results 31 to 40 of about 3,267 (182)
Pre‐clinical efficacy of PU‐H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma [PDF]
Molecular Oncology, 2013 Ewing sarcoma is characterized by multiple deregulated pathways that mediate cell survival and proliferation. Heat shock protein 90 (HSP90) is a critical component of the multi‐chaperone complexes that regulate the disposition and activity of a large number of proteins involved in cell‐signaling systems.
Srikanth R, Ambati +10 more
openaire +2 more sources
DECENTRALIZATION, FISCAL CAPABILITY AND PUBLIC SPENDING EFFICIENCY
Economic Journal of Emerging Markets, 2012 Assigning autonomy to regency governments in Indonesia has failed to increase regency’s economies.While it increases regency government role in planning and initiating policies, its impact oneconomic development has been insignificant.
Abdul Hakim, Jaka Sriyana
doaj +7 more sources
Real Estate Value Tax Based on the Latvian Experience
Real Estate Management and Valuation, 2015 The article deals with the subject of the planned real estate changes in Poland as viewed in relation to the solutions accepted in Latvia. The current basis for real estate tax is a set fee per 1m² of the estate’s area established in a town council ...
Hełdak Maria +2 more
doaj +1 more source
Mitochondria‐Targeting Moieties Based on N‐Tethered Pyridinium Cations
Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.Pyridinium cations were benchmarked as mitochondria‐targeting moieties in a panel of N‐tethered fluorescent‐, bioactive‐, and inert‐cargo conjugates. 3,5‐Diphenylpyridinium (DPPy+) is a competent triphenylphosphonium (TPP+) surrogate, combining high mitochondria‐targeting efficiency with lower intrinsic effects on mitochondrial function.
Ivan Džajić +27 more
wiley +2 more sources
Impact of excise tax on the South African economy: A dynamic CGE approach
Journal of Economics and Management, 2019 Aim/purpose – This paper analyses the impact of excise tax on the South African economy by means of a Dynamic Computable General Equilibrium (CGE) model.
Erero Jean Luc
doaj +1 more source
Naše Gospodarstvo, 2017 Personal income taxation remains an ongoing issue in Croatia. It is used as an important instrument of income redistribution. Moreover, it directly affects purchasing power of the working population.
Palić Irena +2 more
doaj +1 more source
Communications Biology, 2021 Joshi, Gomes et al. employ a chemical modulation approach of the cellular interactome to a hyperconnectivity state and show association with the increased response of pancreatic cancer cell lines to specific drugs, including those that target the MAPK ...
Suhasini Joshi +39 more
doaj +1 more source
Fiscal Capacities of Large Cities in Croatia – Financial Support for Smart Cities
Naše Gospodarstvo, 2020 In a dynamic market, the city has become a main source of competitiveness, along with financial and economic benefits. Due to the processes of digitalization, a new concept has been developed, namely smart cities.
Hodžić Sabina, Paleka Hana
doaj +1 more source
Bell's Palsy in 11,255 Cases: Cardiometabolic Associations in a Population‐Based Healthcare Database
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To estimate Bell's palsy incidence and evaluate the prevalence and associations with diabetes and other cardiometabolic conditions. Study Design Population‐based cohort study. Setting Clalit Health Services, the largest healthcare provider organization in Israel (2005‐2022).
Tomer Boldes +5 more
wiley +1 more source
Biochemical evaluation of the affinity of PU-H71 for PfHsp90.
, 2013 (A) Illustration of geldanamycin (GA, left) and PU-H71 (right) docked within the ATP-binding site of PfHsp90. The models were generated using the PfHsp90 crystal structure (PDB ID: 3K60) [45].
Dylan R. Pillai (239521) +5 more
core +1 more source