Results 51 to 60 of about 3,090 (189)
Naše Gospodarstvo, 2017 Personal income taxation remains an ongoing issue in Croatia. It is used as an important instrument of income redistribution. Moreover, it directly affects purchasing power of the working population.
Palić Irena +2 more
doaj +1 more source
Communications Biology, 2021 Joshi, Gomes et al. employ a chemical modulation approach of the cellular interactome to a hyperconnectivity state and show association with the increased response of pancreatic cancer cell lines to specific drugs, including those that target the MAPK ...
Suhasini Joshi +39 more
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Fiscal Capacities of Large Cities in Croatia – Financial Support for Smart Cities
Naše Gospodarstvo, 2020 In a dynamic market, the city has become a main source of competitiveness, along with financial and economic benefits. Due to the processes of digitalization, a new concept has been developed, namely smart cities.
Hodžić Sabina, Paleka Hana
doaj +1 more source
Biochemical evaluation of the affinity of PU-H71 for PfHsp90.
, 2013 (A) Illustration of geldanamycin (GA, left) and PU-H71 (right) docked within the ATP-binding site of PfHsp90. The models were generated using the PfHsp90 crystal structure (PDB ID: 3K60) [45].
Dylan R. Pillai (239521) +5 more
core +1 more source
Precision Chemistry for Protein Lysine Modification
Chemistry – A European Journal, EarlyView.Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source
STAR Protocols, 2022 Summary: Epichaperomes are disease-associated pathologic scaffolds composed of tightly bound chaperones and co-chaperones. They provide opportunities for precision medicine where aberrant protein-protein interaction networks, rather than a single protein,
Sahil Sharma +8 more
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Assessment of the in vitro antimalarial activity of PU-H71.
, 2013 (A) Antimalarial activity of PU-H71 using a standard SYBR Green cell-based assay using the laboratory strain 3D7 resulted in an IC50 of 89.4±15.3 (SEM) nM (n = 3, performed in duplicate).
Dylan R. Pillai (239521) +5 more
core +1 more source
Supplemental Figure 5 from First-in-Human Trial of Epichaperome-Targeted PET in Patients with Cancer
, 2020 PET detects PU-H71 retention by lymphoma. 62-year-old female with non-Hodgkin lymphoma. 124I-PU-H71 fusion PET/CT (left), CT (middle), and F-18 FDG fusion PET/CT (right) images show corresponding axial planes of chest.
Milan Grkovski (15026429) +22 more
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International Journal of Quantum Chemistry, Volume 126, Issue 12, June 15, 2026.DFT (GGA) analysis reveals that the Rh‐Met metallodrug forms a stable ionic pair driven by a network of supramolecular interactions. QTAIM and IGMH insights elucidate the quantum‐mechanical nature of intra‐ and intermolecular contacts governing its self‐assembly and structural organization in the crystal. ABSTRACT A recently proposed (J. Am. Chem. Soc.
Costantino Zazza +2 more
wiley +1 more source
Supplemental Figure 4 from First-in-Human Trial of Epichaperome-Targeted PET in Patients with Cancer
, 2020 PET detects subcentimeter PU-H71 retention by breast cancer metastases. 65-year-old female with stage IV breast cancer, off-treatment. 124I-PU-H71 PET (right), CT (left), and fusion PET/CT (middle) images show corresponding axial planes of chest ...
Milan Grkovski (15026429) +22 more
core +1 more source