Results 41 to 50 of about 3,267 (182)
Crystal structure of fucoxanthin: resolving a long‐standing crystallographic challenge
The first small‐molecule single‐crystal X‐ray structure of fucoxanthin is reported, resolving a long‐standing crystallographic problem in carotenoid structural chemistry.Fucoxanthin (C42H58O6) is a highly functionalized allenic epoxy xanthophyll containing hydroxy, acetoxy, ketone and conjugated polyene units.
Yui Wakasa, Mao Minoura
wiley +1 more source
Yb[N(CN)2]2Cl·5H2O: The First Mixed‐Anionic Dicyanamide‐Based Chloride Hydrate
The title compound Yb[N(CN)2]2Cl·5H2O crystallizes in the triclinic space group P 1¯$\overline{1}$ with the lattice parameters as a = 926.57(5) pm, b = 1111.65(6) pm, c = 1252.08(7) pm, α = 97.239(2)°, β = 94.641(2)°, γ = 103.038(2)° for Z = 4. Partial metathesis reactions of ytterbium trichloride hexahydrate (YbCl3·6H2O) with silver(I) dicyanamide (Ag[
Ralf J. C. Locke +2 more
wiley +1 more source
Assessment of the in vitro antimalarial activity of PU-H71.
(A) Antimalarial activity of PU-H71 using a standard SYBR Green cell-based assay using the laboratory strain 3D7 resulted in an IC50 of 89.4±15.3 (SEM) nM (n = 3, performed in duplicate).
Dylan R. Pillai (239521) +5 more
core +1 more source
Precision Chemistry for Protein Lysine Modification
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source
Summary: Epichaperomes are disease-associated pathologic scaffolds composed of tightly bound chaperones and co-chaperones. They provide opportunities for precision medicine where aberrant protein-protein interaction networks, rather than a single protein,
Sahil Sharma +8 more
doaj +1 more source
Integrative Analysis Uncover the Effects and Multi‐Omics Features of Thigh Muscle Fat Infiltration
Thigh muscle fat infiltration (TMFI), estimated from MRI, is associated with increased mortality and diseases affecting multiple organ systems and mediates the effects of lifestyle factors on health. Multi‐omics analyses delineate the genetic, cellular, transcriptional, proteomic, and metabolic architecture of TMFI.
Yiwei Zhang +12 more
wiley +1 more source
This paper examines how the demographic and economic structure of the municipalities´ population relates to the share of real property tax on local tax revenue in the Slovak republic.
Lenka Maličká +2 more
doaj +1 more source
The Welfare Effects of Cash Transfers of Electrical Energy Subsidies on Iran Economy [PDF]
Withdrawing energy subsidies has inevitably welfare effects on the Iranian economy. The estimation of this effect can help policy-makers and planners to take the right decisions.
Majid Eslami Andargoly +3 more
doaj
Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source
Semi‐automated MicroED system unveils multiple polymorphs in fish‐derived guanine crystals
A semi‐automated MicroED data collection and processing system was established and shown to be suitable for the structural investigation of submicrometer‐scale biogenic crystals.Certain fish display silvery or blue colour, not through pigments, but through specialized guanine crystals that exist within iridophore cells in their skin. Within these cells,
Minato Nakazawa +6 more
wiley +1 more source

