Results 101 to 110 of about 1,861,445 (361)
We propose a new framework for the simultaneous feedback of stellar winds and photoionizing radiation from massive stars, distinguishing the locations where forces are applied, and consequences for internal spatiotemporal evolution of the whole feedback ...
Lachlan Lancaster +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Using the upGREAT instrument on board the Stratospheric Observatory for Infrared Astronomy, we imaged [C ii ] 157.74 and [O i ] 63.18 μ m line emission from a bright photodissociation region (PDR) associated with an ionized bubble located in the Nessie ...
James M. Jackson +17 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Low-mass Stellar and Substellar Content of the Young Cluster Berkeley 59
We present a multiwavelength analysis of the young star cluster Berkeley 59, based on Gaia data and deep IR observations with the 3.58 m Telescopio Nazionale Galileo and Spitzer space telescope.
Neelam Panwar +6 more
doaj +1 more source
Observations of the molecular gas surrounding the biconical H II region S106 reveal a approx.100 M/sub sun/ disk constraining the development of the ionized region. Two CO peaks are seen in the equatorial plane of the biconical nebula on opposite sides of a near infrared source thought to be the exciting star for the H II region. Although no systematic
J. Bally, N. Z. Scoville
openaire +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Detection of Diffuse Hot Gas around the Young, Potential Superstar Cluster H72.97–69.39
We present the first Chandra X-ray observations of H72.97–69.39, a highly embedded, potential superstar cluster in its infancy located in the star-forming complex N79 of the Large Magellanic Cloud. We detect particularly hard, diffuse X-ray emission that
Trinity L. Webb +8 more
doaj +1 more source

