Results 111 to 120 of about 1,861,445 (361)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

ALMA-QUARKS: Few-thousand-year “Hatching out of the Egg:” The Supersonic Breakout of a Hypercompact H II Region from Its Parental Hot Core

open access: yesThe Astrophysical Journal
The kinematic evolution of hypercompact (HC) H ii regions around young high-mass stars remains poorly understood due to complex interactions with parental environs.
Siju Zhang   +21 more
doaj   +1 more source

He II emission in extragalactic H II regions

open access: yesThe Astrophysical Journal, 1991
Spectroscopic observations confirming the presence of nebular He II 4686-A emission in the SMC H II region N76 are presented, and it is demonstrated that the He II emission associated with the WO star in IC 1613 is also extended. The properties of four H II regions are discussed.
Donald R. Garnett   +3 more
openaire   +1 more source

Radiation hydrodynamic simulations of massive star formation via gravitationally trapped H ii regions – spherically symmetric ionized accretion flows [PDF]

open access: green, 2019
Kristin Lund   +7 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Magnetic Field Alignment Relative to Multiple Tracers in the High-mass Star-forming Region RCW 36

open access: yesThe Astrophysical Journal
We use polarization data from SOFIA HAWC+ to investigate the interplay between magnetic fields and stellar feedback in altering gas dynamics within the high-mass star-forming region RCW 36, located in Vela C.
Akanksha Bij   +11 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The Population of H ii Regions in NGC 7020 [PDF]

open access: bronze, 2021
H. Dottori   +4 more
openalex   +1 more source

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