Results 141 to 150 of about 1,094,944 (319)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The Nearest H II Regions.

The Astrophysical Journal, 1952
Stewart Sharpless, Donald Osterbrock
openaire   +1 more source

Clumpy ultracompact H II regions – I. Fully supersonic wind-blown models [PDF]

, 1995
J. E. Dyson, R. J. R. Williams, M. P. Redman   +2 more
openalex   +1 more source

The Population of H ii Regions in NGC 7020 [PDF]

, 2021
H. Dottori, Rubén Díaz, P. Grosbøl, A. Bueno, G. Gimeno   +4 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

DYNAMICS OF H II REGIONS [PDF]

Proceedings of the National Academy of Sciences, 1963
openaire   +1 more source

Isolated Extragalactic H II Regions

The Astrophysical Journal, 1970
Wallace L. W. Sargent, Leonard Searle
openaire   +1 more source

THE METALLICITY PROFILE OF M31 FROM SPECTROSCOPY OF HUNDREDS OF H II REGIONS AND PNe [PDF]

, 2012
Nathan E. Sanders, Nelson Caldwell, Jonathan McDowell, Paul Harding   +3 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Studies of ultracompact H II regions -- III. Near-infrared survey of selected regions [PDF]

, 1999
Andrew Walsh, Michael Burton, A. R. Hyland, G. Robinson   +3 more
openalex   +1 more source