Results 1 to 10 of about 10,512 (289)

Paraspinal extramedullary haematopoiesis in a patient with sickle cell disease: a rare clinical presentation [PDF]

European Journal of Case Reports in Internal Medicine
Background: Extramedullary haematopoiesis refers to the formation of blood cells outside the bone marrow, typically as a compensatory response to chronic anaemia or bone marrow failure.
Anurag Raje, Gowtham Siddi, Amita D'Souza, Amit Correa   +3 more
doaj   +2 more sources

Faster postnatal decline in hepatic erythropoiesis than granulopoiesis in human newborns [PDF]

Frontiers in Pediatrics
BackgroundDuring human foetal development, the liver is the primary site of blood cell production, but this activity declines in the third trimester and postnatally as haematopoiesis shifts to bone marrow.
Petra Janovska, Kristina Bardova, Zuzana Prouzova, Zuzana Prouzova, Ilaria Irodenko, Tatyana Kobets, Eliska Haasova, Eliska Haasova, Lenka Steiner Mrazova, Lenka Steiner Mrazova, Viktor Stranecky, Stanislav Kmoch, Martin Rossmeisl, Petr Zouhar, Jan Kopecky   +14 more
doaj   +2 more sources

Haematopoiesis in Zebrafish (Danio Rerio)

Frontiers in Immunology, 2022
Haematopoiesis in fish and mammals is a complex process, and many aspects regarding its model and the differentiation of haematopoietic stem cells (HSCs) still remain enigmatic despite advanced studies.
Michał Stosik, Beata Tokarz-Deptuła, Wiesław Deptuła   +2 more
doaj   +1 more source

Association of clonal haematopoiesis with recurrent venous thromboembolism: A case-control study. [PDF]

Br J Haematol
Englisch C, Vostatek R, Schramm T, Binder CJ, Pabinger I, Jäger R, Ay C.   +6 more
europepmc   +3 more sources

New light shed on the early evolution of limb-bone growth plate and bone marrow

eLife, 2021
The production of blood cells (haematopoiesis) occurs in the limb bones of most tetrapods but is absent in the fin bones of ray-finned fish. When did long bones start producing blood cells?
Jordi Estefa, Paul Tafforeau, Alice M Clement, Jozef Klembara, Grzegorz Niedźwiedzki, Camille Berruyer, Sophie Sanchez   +6 more
doaj   +1 more source

Retinoic acid receptor regulation of decision-making for cell differentiation

Frontiers in Cell and Developmental Biology, 2023
All-trans retinoic acid (ATRA) activation of retinoic acid receptors (RARs) is crucial to an organism’s proper development as established by findings for mouse foetuses from dams fed a vitamin A-deficient diet.
Geoffrey Brown
doaj   +1 more source

Searching for the Origin and the Differentiation of Haemocytes before and after Larval Settlement of the Colonial Ascidian Botryllus schlosseri: An Ultrastructural Viewpoint

Journal of Marine Science and Engineering, 2022
The colonial ascidian Botryllus schlosseri possesses an innate immunity, which plays fundamental roles in its survival, adaptability, worldwide spread and ecological success.
Francesca Cima
doaj   +1 more source

Zoledronic acid inhibits the growth of leukemic MLL-AF9 transformed hematopoietic cells

Heliyon, 2020
A leukemic in vitro model produced by transducing Cord Blood derived-hematopoietic CD34+ cells with the MLL-AF9 translocation resulting in the oncogenic fusion protein, is used to assess for sensitivity to Zoledronic acid.
Emanuela Chiarella, Bruna Codispoti, Annamaria Aloisio, Emanuela G. Cosentino, Stefania Scicchitano, Ylenia Montalcini, Daniela Lico, Giovanni Morrone, Maria Mesuraca, Heather M. Bond   +9 more
doaj   +1 more source

GATA2 mitotic bookmarking is required for definitive haematopoiesis

Nature Communications, 2023
In mitosis, most transcription factors detach from chromatin, but some are retained and bookmark genomic sites. Mitotic bookmarking has been implicated in lineage inheritance, pluripotency and reprogramming.
Rita Silvério-Alves, Ilia Kurochkin, Anna Rydström, Camila Vazquez Echegaray, Jakob Haider, Matthew Nicholls, Christina Rode, Louise Thelaus, Aida Yifter Lindgren, Alexandra Gabriela Ferreira, Rafael Brandão, Jonas Larsson, Marella F. T. R. de Bruijn, Javier Martin-Gonzalez, Carlos-Filipe Pereira   +14 more
doaj   +1 more source

Monocytes, Macrophages, and Metabolic Disease in Atherosclerosis

Frontiers in Pharmacology, 2019
Atherosclerotic cardiovascular disease (CVD) is a lipid-driven chronic inflammatory disease, in which macrophages are responsible for taking up these lipids and driving disease progression.
Michelle C. Flynn, Gerard Pernes, Man Kit Sam Lee, Prabhakara R. Nagareddy, Andrew J. Murphy   +4 more
doaj   +1 more source