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Haematopoiesis in Zebrafish (Danio Rerio)
Frontiers in Immunology, 2022 Haematopoiesis in fish and mammals is a complex process, and many aspects regarding its model and the differentiation of haematopoietic stem cells (HSCs) still remain enigmatic despite advanced studies.
Michał Stosik +2 more
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Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
Nature Communications, 2016 Clonal haematopoiesis has been thought to occur in less than 10% of individuals younger than 70 years old. Here, the authors use an error corrected next-generation sequencing method to find clonal haematopoiesis in the peripheral blood of 19 of 20 ...
Andrew L. Young +3 more
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Extramedullary haematopoiesis in the kidney [PDF]
Clinical Kidney Journal, 2012 Extramedullary haematopoiesis (EMH) is the development of haematopoietic tissue outside the bone marrow and it most often occurs in the liver and spleen. Renal EMH is quite rare and there are very few case reports concerning the kidney. We describe two cases of 'renal histologically documented EMH' and, in particular, in the second of these two, the ...
Davide Ricci +4 more
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MicroRNAs as Haematopoiesis Regulators
Advances in Hematology, 2013 The production of different types of blood cells including their formation, development, and differentiation is collectively known as haematopoiesis.
Ram Babu Undi +2 more
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Adhesion Molecules Involved in Stem Cell Niche Retention During Normal Haematopoiesis and in Acute Myeloid Leukaemia [PDF]
Frontiers in Immunology, 2021 In the bone marrow (BM) of adult mammals, haematopoietic stem cells (HSCs) are retained in micro-anatomical structures by adhesion molecules that regulate HSC quiescence, proliferation and commitment.
Julien M. P. Grenier +4 more
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South African Medical Journal, 2019 Human immunodeficiency virus (HIV) infection not only leads to a compromised immune system, but also disrupts normal haematopoiesis, resulting in the frequent manifestation of cytopenias (anaemia, thrombocytopenia and neutropenia). Although there is a definite association between the severity of cytopenia and HIV disease stage, this relationship is not
Chrisna Durandt +7 more
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Irradiation Haematopoiesis Recovery Orchestrated by IL-12/IL-12Rβ1/TYK2/STAT3-Initiated Osteogenic Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells [PDF]
Frontiers in Cell and Developmental Biology, 2021 PurposeRepairing the irradiation-induced osteogenic differentiation injury of bone marrow mesenchymal stem cells (BM-MSCs) is beneficial to recovering haematopoiesis injury in radiotherapy; however, its mechanism is elusive.
Fengjie Li +10 more
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A newly identified gene Ahed plays essential roles in murine haematopoiesis [PDF]
Nature CommunicationsThe development of haematopoiesis involves the coordinated action of numerous genes, some of which are implicated in haematological malignancies. However, the biological function of many genes remains elusive and unknown functional genes are likely to ...
Ritsuko Nakai +19 more
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Disordered haematopoiesis and athero-thrombosis [PDF]
European Heart Journal, 2016 Atherosclerosis, the major underlying cause of cardiovascular disease, is characterized by a lipid-driven infiltration of inflammatory cells in large and medium arteries. Increased production and activation of monocytes, neutrophils, and platelets, driven by hypercholesterolaemia and defective high-density lipoproteins-mediated cholesterol efflux ...
Andrew Murphy, Alan R. Tall
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The embryonic origins of human haematopoiesis [PDF]
British Journal of Haematology, 2001 Caroline Marshall, Adrian J. Thrasher
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