Results 11 to 20 of about 22,415 (245)

Optimal experimental design for mathematical models of haematopoiesis. [PDF]

, 2021
The haematopoietic system has a highly regulated and complex structure in which cells are organized to successfully create and maintain new blood cells.
Iniguez, Abdon, Jena, Nilamani, Lander, Arthur D, Liu, Zhong-Ying, Lomeli, Luis Martinez, Lowengrub, John S, Minin, Vladimir N, Shahbaba, Babak, Tata, Prasanthi, Van Etten, Richard   +9 more
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Heterochromatin and Polycomb as regulators of haematopoiesis [PDF]

Biochemical Society Transactions, 2021
Haematopoiesis is the process by which multipotent haematopoietic stem cells are transformed into each and every type of terminally differentiated blood cell. Epigenetic silencing is critical for this process by regulating the transcription of cell-cycle genes critical for self-renewal and differentiation, as well as restricting alternative fate genes ...
Christine R. Keenan, Christine R. Keenan
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Pulmonary extramedullary haematopoiesis [PDF]

Case Reports, 2011
A 72-year-old Caucasian lady with myeloproliferative disorder was admitted for evaluation of progressive dyspnoea, weight loss, fatigue and mild hypoxia. A diffuse ground glass opacity was seen on CT pulmonary angiogram. Differential diagnoses included heart failure, infection, progression of myeloproliferative disorder with extramedullary ...
Stephen Fanning, Veenu Mubarak, Simon D. Bowler, Morgon Windsor, Edwina Duhig   +4 more
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The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain [PDF]

, 2020
Chromatin remodelling and transcription factors play important roles in lineage commitment and development through control of gene expression. Activation of selected lineage-specific genes and repression of alternative lineage-affiliated genes results in
Biasutto, Antonio J, Gilbert, Robert C G, Karia, Dimple, Mancini, Erika J, Porcher, Catherine   +4 more
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Germline risk of clonal haematopoiesis [PDF]

Nature Reviews Genetics, 2021
Clonal haematopoiesis (CH) is a common, age-related expansion of blood cells with somatic mutations that is associated with an increased risk of haematological malignancies, cardiovascular disease and all-cause mortality. CH may be caused by point mutations in genes associated with myeloid neoplasms, chromosomal copy number changes and loss of ...
Alexander J. Silver, Alexander G. Bick, Michael R. Savona   +2 more
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The MLL/SET family and haematopoiesis [PDF]

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020
As demonstrated through early work in Drosophila, members of the MLL/SET family play essential roles during embryonic development through their participation in large protein complexes that are central to epigenetic regulation of gene expression. One of its members, MLL1, has additionally received a lot of attention as it is a potent oncogenic driver ...
Antunes, Eric, Ottersbach, Katrin
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Extramedullary haematopoiesis in the kidney [PDF]

Clinical Kidney Journal, 2012
Extramedullary haematopoiesis (EMH) is the development of haematopoietic tissue outside the bone marrow and it most often occurs in the liver and spleen. Renal EMH is quite rare and there are very few case reports concerning the kidney. We describe two cases of 'renal histologically documented EMH' and, in particular, in the second of these two, the ...
Elena Sabattini, Massimo Valentino, Antonio Santoro, Marcora Mandreoli, Davide Ricci   +4 more
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Zebrafish Caudal Haematopoietic Embryonic Stromal Tissue (CHEST) Cells Support Haematopoiesis. [PDF]

, 2017
Haematopoiesis is an essential process in early vertebrate development that occurs in different distinct spatial locations in the embryo that shift over time.
Aggio, Julian, Campbell, Clyde, Marquez, Gabriel, Stachura, David L, Traver, David, Wolf, Anja, Wright, Francis   +6 more
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Drosophila haematopoiesis

Cellular Microbiology, 2007
Like in vertebrates, Drosophila haematopoiesis occurs in two waves. It gives rise to three types of haemocytes: plasmatocytes (phagocytosis), crystal cells (melanization) and lamellocytes (encapsulation of parasites). A first population of haemocytes, specified during embryogenesis, gives rise to an invariant number of plasmatocytes and crystal cells ...
Crozatier, Michèle, Meister, Marie
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Mechanisms controlling anaemia in Trypanosoma congolense infected mice. [PDF]

, 2009
Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa.
A Kobayashi, A Shamseddine, AI Su, AJ Nok, Andy Brass, B Mertens, B Stijlemans, B Stijlemans, B Vanhollebeke, Birgit Rathkolb, BM Bolstad, C Beaumont, C Li, CA Facer, CA Schaer, Delnaz Roshandel, DM Wrighting, E Nemeth, E Nemeth, E Nemeth, Eckard Wolf, Fuad Iraqi, G Weiss, Gd Haan, Gordon Langsley, Harry A. Noyes, HC Greenblatt, Helen Hulme, Helmut Fuchs, HH Kazazian, J Naessens, J Naessens, J Naessens, J Naessens, Jan Naessens, JCM Trail, KAN Esievo, KC Corbit, LY Shih, M Murray, M Murray, M Shi, M Shi, M Sileghem, M Sileghem, Martin Hrabé de Angelis, Mohammad H. Alimohammadian, Morris Agaba, MR Rifkin, N Mabbott, O Van Assendaelft, PM Kristjanson, R Ferreira, RC Gregory, RH Wang, RKG Assoku, RM Ngure, S Kemp, S Kierstein, S Magez, S Magez, S Taniguchi, SH Goh, SJ Kemp, SK Moestrup, Stephen Kemp, T Sato, TC Cheng, Valerie Gailus-Durner, VO Anosa, W Morrison, W Morrison, W Zumkeller, Y Liang, Y Nakamura   +74 more
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