Results 241 to 250 of about 13,881 (340)

Blood-generating heart-forming organoids recapitulate co-development of the human haematopoietic system and the embryonic heart. [PDF]

Nat Cell Biol
Dardano M, Kleemiß F, Kosanke M, Lang D, Wilson L, Franke A, Teske J, Shivaraj A, de la Roche J, Fischer M, Lange L, Schambach A, Drakhlis L, Zweigerdt R.   +13 more
europepmc   +1 more source

Characterization of Genetic Landscape and Novel Inflammatory Biomarkers in Patients With Adult‐Onset Still's Disease

Arthritis &Rheumatology, EarlyView.
Objective Adult‐onset Still disease (AOSD) is a systemic autoinflammatory disorder (AID) of unknown etiology. Genetic studies have been limited. Here, we conducted detailed genetic and inflammatory biomarker analysis of a large cohort with AOSD to investigate the underlying pathology and identify novel targets for potential treatment.
Joanne Topping, Leon Chang, Fatima Nadat, James A. Poulter, Alice Ibbotson, Samuel Lara‐Reyna, Christopher M. Watson, Clive Carter, Linda P. Pournara, Jan Zernicke, Rebecca L. Ross, Catherine Cargo, Paul A. Lyons, Kenneth G. C. Smith, Francesco Del Galdo, Jürgen Rech, Bruno Fautrel, Eugen Feist, Michael F. McDermott, Sinisa Savic, on behalf of the ImmunAID Consortium   +20 more
wiley   +1 more source

Error-corrected ultradeep next-generation sequencing for detection of clonal haematopoiesis and haematological neoplasms - sensitivity, specificity and accuracy. [PDF]

PLoS One
Tursky ML, Artuz CM, Rapadas M, Wittert GA, Molloy TJ, Ma DD.   +5 more
europepmc   +1 more source

Humanised mouse models for haematopoiesis and infectious diseases

, 2017
Veronika Lysenko, Donal McHugh, Lena Behrmann, Mary-Aude Rochat, C. Matthias Wilk, Larisa V. Kovtonyuk, Jean‐Pierre Bourquin, Christian Münz, Markus G. Manz, Roberto F. Speck, Alexandre Theocharides   +10 more
openalex   +1 more source

Substitution of Glutamic Acid at Position 71 of DRβ1*04:01 and Collagen‐Specific Tolerance Without Alloreactivity

Arthritis &Rheumatology, EarlyView.
Objective The DRB1 locus is strongly associated with both susceptibility and resistance to rheumatoid arthritis (RA). DRB1 alleles encoding the VKA or VRA epitope in positions 11, 71, and 74 confer the highest risk of developing RA, whereas the allele encoding VEA is protective.
Vibha Jha, Brian M. Freed, Elizabeth R. Sunderhaus, Jessica E. Lee, Edward B. Prage, Manjula Miglani, Edward F. Rosloniec, Jennifer L. Matsuda, Marilyne G. Coulombe, Amy S. McKee, Christina L. Roark   +10 more
wiley   +1 more source

Anti-Inflammatory Resveratrol Protects Mice From Early Mortality After Haematopoietic Stem Cell Transplantation. [PDF]

J Cell Mol Med
Zhang X, Yu W, Sun Y, Ye X, He Y, Huang X, Wang F, Lu Y, Zhang J.   +8 more
europepmc   +1 more source

Endometrial and cervical osseous metaplasia with extramedullary haematopoiesis presenting as amenorrhea: Report of three cases

, 2020
Rakesh Kumar Gupta, Iffat Jamal, Surabhi Raj, Punam Prasad Bhadani   +3 more
openalex   +1 more source

Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation for Diffuse Cutaneous Systemic Sclerosis: Identifying Disease Risk Factors for Toxicity and Long‐Term Outcomes in a Prospective, Single‐Arm Trial

Arthritis &Rheumatology, EarlyView.
Objective Two randomized trials for patients with diffuse systemic sclerosis (SSc) demonstrated an overall survival (OS) and event‐free survival (EFS) advantage of autologous hematopoietic stem cell transplantation (AHSCT) using CD34+ selected peripheral blood stem cells (PBSCs) compared with monthly cyclophosphamide (CY).
George E. Georges, Dinesh Khanna, Mark H. Wener, Matthew G. Mei, Maureen D. Mayes, Robert W. Simms, Vaishali Sanchorawala, Chitra Hosing, Suzanne Kafaja, Attaphol Pawarode, Leona A. Holmberg, Jason Kolfenbach, Daniel E. Furst, Keith M. Sullivan, Suiyuan Huang, Ted Gooley, Richard A. Nash   +16 more
wiley   +1 more source

Spatial transcriptomic approaches for characterising the bone marrow landscape: pitfalls and potential. [PDF]

Leukemia
Cooper RA, Thomas E, Sozanska AM, Pescia C, Royston DJ.   +4 more
europepmc   +1 more source

Maintenance of primitive haematopoiesis is shared by SCL and LYL1

, 2017
Sung Kai Chiu, Jesslyn Saw, Yizhou Huang, Dominic Beck, David Powell, John E. Pimanda, Cédric S. Tremblay, David J. Curtis   +7 more
openalex   +1 more source