Results 31 to 40 of about 16,847 (244)
Journal of Blood Medicine, 2022 Budi Santosa,1 Ali Rosidi,2 Herlisa Anggraini,3 Zahra Maharani Latrobdiba,2 Fitriani Nur Damayanti,4 Heru Santoso Wahito Nugroho5 1Department of Medical Laboratory Science, Universitas Muhammadiyah Semarang, Semarang, Indonesia; 2Department of Nutrition,
Santosa B +5 more
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Cells, 2020 Acute myeloid leukaemia (AML) is a haematopoietic malignancy caused by a combination of genetic and epigenetic lesions. Activation of the oncoprotein FLT3 ITD (Fms-like tyrosine kinase with internal tandem duplications) represents a key driver mutation ...
Isabel Bär +6 more
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CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development [PDF]
, 2011 The C-type lectin receptor CLEC-2 signals through a pathway that is critically dependent on the tyrosine kinase Syk. We show that homozygous loss of either protein results in defects in brain vascular and lymphatic development, lung inflation and ...
Abramoff +66 more
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Therapeutic Modulation of Autophagy in Leukaemia and Lymphoma
Cells, 2019 Haematopoiesis is a tightly orchestrated process where a pool of hematopoietic stem and progenitor cells (HSPCs) with high self-renewal potential can give rise to both lymphoid and myeloid lineages.
Mojgan Djavaheri-Mergny +3 more
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Preliminary investigation of the effects of long-term dietary intake of genistein and daidzein on hepatic histopathology and biochemistry in domestic cats (Felis catus) [PDF]
, 2012 Dietary isoflavones have been hypothesised to play a role in hepatic veno-occlusive disease in captive exotic felids, although empirical evidence is lacking. This study aimed to investigate the effect of long-term (>1 year) dietary genistein and daidzein
Cave, NJ +4 more
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Effect of simvastatin on thrombopoiesis in porcine bone marrow
Journal of Veterinary Research, 2019 Introduction: Statins are pharmacological agents commonly used to lower serum cholesterol level. The aim of the experiment was to investigate the effect of the statin simvastatin on thrombopoiesis in the porcine model because it is the closest to the ...
Snarska Anna +2 more
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Frontiers in Cell and Developmental Biology, 2021 PurposeRepairing the irradiation-induced osteogenic differentiation injury of bone marrow mesenchymal stem cells (BM-MSCs) is beneficial to recovering haematopoiesis injury in radiotherapy; however, its mechanism is elusive.
Fengjie Li +10 more
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Identification of stromal cells in spleen which support myelopoiesis [PDF]
, 2019 Stromal cells in spleen organize tissue into red pulp, white pulp and marginal zone, and also interact with hematopoietic cells to regulate immune responses.
Lim, Hong, O'Neill, Helen C
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Disease Models & Mechanisms, 2021 Down syndrome (DS), trisomy 21, results in many complex phenotypes including cognitive deficits, heart defects and craniofacial alterations. Phenotypes arise from an extra copy of human chromosome 21 (Hsa21) genes.
Eva Lana-Elola +25 more
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The role of the CCN family of proteins in blood cancers [PDF]
, 2016 Haematopoiesis is the term used to describe the production of blood cells. This is a tightly regulated hierarchical system in which mature circulating blood cells develop from a small population of haematopoietic stem (HSC) and progenitor cells within ...
Crawford, Lisa Judith +1 more
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