Results 41 to 50 of about 28,636 (337)
Mechanisms controlling anaemia in Trypanosoma congolense infected mice. [PDF]
Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa.
A Kobayashi+74 more
core +3 more sources
Updates on Old and Weary Haematopoiesis [PDF]
Blood formation, or haematopoiesis, originates from haematopoietic stem cells (HSCs), whose functions and maintenance are regulated in both cell- and cell non-autonomous ways. The surroundings of HSCs in the bone marrow create a specific niche or microenvironment where HSCs nest that allows them to retain their unique characteristics and respond ...
Joanna Konieczny, Lorena Arranz
openaire +5 more sources
Regulation of NF-κB by PML and PML-RARα [PDF]
Promyelocytic Leukemia (PML) is a nuclear protein that forms sub-nuclear structures termed nuclear bodies associated with transcriptionally active genomic regions. PML is a tumour suppressor and regulator of cell differentiation.
Ahmed, Abrar+8 more
core +1 more source
Introduction Around 5% of the world’s population is expected to have some degree and type of thalassaemia. Beta thalassaemia (BT) occurs due to a deficient production of the beta-globin chain of haemoglobin.
Eihab A Subahi+7 more
semanticscholar +1 more source
Unlocking the potential of anti-CD33 therapy in adult and childhood acute myeloid leukaemia [PDF]
Acute Myeloid Leukaemia (AML) develops when there is a block in differentiation and uncontrolled proliferation of myeloid precursors, resulting in bone marrow failure.
Gibson, Brenda E.S.+3 more
core +1 more source
Predictors and Consequences of Anaemia Among Antiretroviral-Naïve HIV-Infected and HIV-Uninfected Children in Tanzania. [PDF]
Predictors and consequences of childhood anaemia in settings with high HIV prevalence are not well known. The aims of the present study were to identify maternal and child predictors of anaemia among children born to HIV-infected women and to study the ...
Adewuyi+13 more
core +1 more source
MicroRNAs as Haematopoiesis Regulators
The production of different types of blood cells including their formation, development, and differentiation is collectively known as haematopoiesis. Blood cells are divided into three lineages erythriod (erythrocytes), lymphoid (B and T cells), and myeloid (granulocytes, megakaryocytes, and macrophages).
Ravi Kumar Gutti+2 more
openaire +4 more sources
Decoding human fetal liver haematopoiesis
Definitive haematopoiesis in the fetal liver supports self-renewal and differentiation of haematopoietic stem cells and multipotent progenitors (HSC/MPPs) but remains poorly defined in humans.
Dorin-Mirel Popescu+55 more
semanticscholar +1 more source
Deciphering cell states and genealogies of human haematopoiesis
The human blood system is maintained through the differentiation and massive amplification of a limited number of long-lived haematopoietic stem cells (HSCs)1. Perturbations to this process underlie diverse diseases, but the clonal contributions to human
Chen Weng+26 more
semanticscholar +1 more source
Identification of stromal cells in spleen which support myelopoiesis [PDF]
Stromal cells in spleen organize tissue into red pulp, white pulp and marginal zone, and also interact with hematopoietic cells to regulate immune responses.
Lim, Hong, O'Neill, Helen C
core +2 more sources