Results 41 to 50 of about 22,731 (338)

Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner [PDF]

, 2021
journal ...
Hirao Atsushi, Ito Chiaki, Kasahara Atsuko, Kobayashi Masahiko, Kohno Susumu, Komatsu Masaaki, Kurayoshi Kenta, Nomura Naho, Ooshio Takako, Si Sha, Tadokoro Yuko, Takahashi Chiaki, Takase Yusuke, Ueno Masaya, Yanagawa Toru   +14 more
core   +4 more sources

SOX7-enforced expression promotes the expansion of adult blood progenitors and blocks B-cell development [PDF]

Open Biology, 2016
During embryogenesis, the three SOXF transcription factors, SOX7, SOX17 and SOX18, regulate the specification of the cardiovascular system and are also involved in the development of haematopoiesis.
Sara Cuvertino, Georges Lacaud, Valerie Kouskoff   +2 more
doaj   +1 more source

Irradiation Haematopoiesis Recovery Orchestrated by IL-12/IL-12Rβ1/TYK2/STAT3-Initiated Osteogenic Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells

Frontiers in Cell and Developmental Biology, 2021
PurposeRepairing the irradiation-induced osteogenic differentiation injury of bone marrow mesenchymal stem cells (BM-MSCs) is beneficial to recovering haematopoiesis injury in radiotherapy; however, its mechanism is elusive.
Fengjie Li, Rong Zhang, Changpeng Hu, Qian Ran, Yang Xiang, Lixin Xiang, Li Chen, Yang Yang, Shengwen Calvin Li, Gang Zhang, Zhongjun Li   +10 more
doaj   +1 more source

Preliminary investigation of the effects of long-term dietary intake of genistein and daidzein on hepatic histopathology and biochemistry in domestic cats (Felis catus) [PDF]

, 2012
Dietary isoflavones have been hypothesised to play a role in hepatic veno-occlusive disease in captive exotic felids, although empirical evidence is lacking. This study aimed to investigate the effect of long-term (>1 year) dietary genistein and daidzein
Cave, NJ, Roe, WD, Thomas, DG, Ugarte, CE, Whitehouse-Tedd, KM   +4 more
core   +1 more source

Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes

Disease Models & Mechanisms, 2021
Down syndrome (DS), trisomy 21, results in many complex phenotypes including cognitive deficits, heart defects and craniofacial alterations. Phenotypes arise from an extra copy of human chromosome 21 (Hsa21) genes.
Eva Lana-Elola, Heather Cater, Sheona Watson-Scales, Simon Greenaway, Jennifer Müller-Winkler, Dorota Gibbins, Mihaela Nemes, Amy Slender, Tertius Hough, Piia Keskivali-Bond, Cheryl L. Scudamore, Eleanor Herbert, Gareth T. Banks, Helene Mobbs, Tara Canonica, Justin Tosh, Suzanna Noy, Miriam Llorian, Patrick M. Nolan, Julian L. Griffin, Mark Good, Michelle Simon, Ann-Marie Mallon, Sara Wells, Elizabeth M. C. Fisher, Victor L. J. Tybulewicz   +25 more
doaj   +1 more source

A gene trap transposon eliminates haematopoietic expression of zebrafish Gfi1aa, but does not interfere with haematopoiesis [PDF]

, 2016
A transposon-mediated gene trap screen identified the zebrafish line qmc551 that expresses a GFP reporter in primitive erythrocytes and also in haemogenic endothelial cells, which give rise to haematopoietic stem and progenitor cells (HSPCs) that seed ...
Aday, Bertrand, Bjerknes, Boisset, Broadbent, Burns, Butko, Chen, Chen, Chris Moore, Ciau-Uitz, Clements, Cooney, de Bruijn, Deniz Ucanok, Detrich, Doan, Doulatov, Dufourcq, Ellett, Fiolka, Flicek, Frame, Frame, Geling, Gering, Gering, Gerlach, Gordon-Keylock, Gray, Haddon, Herbomel, Hock, Hock, Huber, Itoh, Jin, Kalev-Zylinska, Karsunky, Kathryn McMahon, Khandanpour, Kissa, Kissa, Kohli, Kotani, Lam, Lancrin, Lawson, Le Guyader, Liao, Ma, Martin Gering, Maryam Jalali, Medvinsky, Medvinsky, Moignard, Montoya-Durango, Murayama, Möröy, Orkin, Palis, Qian, Renaud, Robert Neil Wilkinson, Robu, Roshana Thambyrajah, Rowlinson, Saleque, Schoenebeck, Sieger, Stainier, Tamplin, Taoudi, Thambyrajah, Tober, Traver, Wallis, Wei, Weinstein, Yasmin Hough, Yokomizo, Yücel, Zeng, Zhen, Zovein   +84 more
core   +2 more sources

Mask Protection Against Lead Exposure and Its Correlation with Erythropoiesis in Automotive Body Painters at Ligu District, Semarang, Indonesia

Journal of Blood Medicine, 2022
Budi Santosa,1 Ali Rosidi,2 Herlisa Anggraini,3 Zahra Maharani Latrobdiba,2 Fitriani Nur Damayanti,4 Heru Santoso Wahito Nugroho5 1Department of Medical Laboratory Science, Universitas Muhammadiyah Semarang, Semarang, Indonesia; 2Department of Nutrition,
Santosa B, Rosidi A, Anggraini H, Latrobdiba ZM, Damayanti FN, Nugroho HSW   +5 more
doaj  

Infant leukaemia – faithful models, cell of origin and the niche

Disease Models & Mechanisms, 2021
For patients and their families, the diagnosis of infant leukaemia is devastating. This disease has not seen the improvements in outcomes experienced with other paediatric leukaemias and it is becoming ever more apparent that infant leukaemia is a ...
Alasdair Duguid, Domenico Mattiucci, Katrin Ottersbach   +2 more
doaj   +1 more source

Bivalve Haemocyte Subpopulations: A Review

Frontiers in Immunology, 2022
Bivalve molluscs stand out for their ecological success and their key role in the functioning of aquatic ecosystems, while also constituting a very valuable commercial resource. Both ecological success and production of bivalves depend on their effective
Nuria R. de la Ballina, Francesco Maresca, Asunción Cao, Antonio Villalba, Antonio Villalba, Antonio Villalba   +5 more
doaj   +1 more source

Effect of simvastatin on thrombopoiesis in porcine bone marrow

Journal of Veterinary Research, 2019
Introduction: Statins are pharmacological agents commonly used to lower serum cholesterol level. The aim of the experiment was to investigate the effect of the statin simvastatin on thrombopoiesis in the porcine model because it is the closest to the ...
Snarska Anna, Wysocka Dominika, Rytel Liliana   +2 more
doaj   +1 more source