Results 101 to 110 of about 22,562,840 (346)

Reliability and validity of a novel haemophilia-specific self-efficacy scale [PDF]

, 2014
Higher self-efficacy in chronic disease patients is associated with higher development of self-management skills and increased quality-of-life. Quantification and monitoring of self-efficacy is therefore of importance.
Cnossen, M.H. (Marjon), Leebeek, F.W.G. (Frank), Lock, J. (Janske), Moll, H.A. (Henriëtte), Peters, M.A.D. (Marjolein), Raat, H. (Hein), Tamminga, R.   +6 more
core   +2 more sources

The experiences of people with haemophilia and their families of gene therapy in a clinical trial setting: regaining control, the Exigency study

Orphanet Journal of Rare Diseases, 2022
Background Gene therapy has the potential to change the life experience of people with haemophilia and family members. Few studies have sought to explore the impact of gene therapy on both individuals and families.
Simon Fletcher, Kathryn Jenner, Luke Pembroke, Michael Holland, Kate Khair   +4 more
doaj   +1 more source

Investigating the role of SARM1 in central nervous system

Ibrain, EarlyView.
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang, Yuhang Shi, Jinglei Tian, Liming Tang, Fang Cao   +4 more
wiley   +1 more source

Long‐term safety and efficacy of recombinant factor VIII Fc fusion protein (rFVIIIFc) in subjects with haemophilia A

Haemophilia, 2016
The safety, efficacy and prolonged half‐life of recombinant factor VIII Fc fusion protein (rFVIIIFc) in previously treated patients with severe haemophilia A was demonstrated in the phase 3 A‐LONG and Kids A‐LONG studies.
B. Nolan, J. Mahlangu, David J. Perry, Guy Young, R. Liesner, Barbara A Konkle, Savita Rangarajan, S. A. Brown, H. Hanabusa, K. J. Pasi, Ingrid Pabinger, Shannon Jackson, L. Cristiano, X. Li, Glenn F Pierce, G. Allen   +15 more
semanticscholar   +1 more source

Evaluation of coagulation disorders and iron deficiency in women with heavy menstrual bleeding

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To explore the incidence of congenital bleeding disorders (CBD), which may result in anemia, in a large cohort of women referred for heavy menstrual bleeding (HMB) in a specialized gynecologic unit. Methods Between January 2022 and January 2024, all women referred for HMB were screened.
Lucia Rugeri, Yelena Fruchou, Caroline Brodbeck, Marianne Bastien, Amandine Lioux, Giulia Gouy, Marion Cortet, Gil Dubernard, Yesim Dargaud   +8 more
wiley   +1 more source

The impact of severe haemophilia and the presence of target joints on health-related quality-of-life [PDF]

, 2018
Background: Joint damage remains a major complication associated with haemophilia and is widely accepted as one of the most debilitating symptoms for persons with severe haemophilia.
Camp, Charlotte, Carroll, Liz, Hoxer, Christina, Mazza, Giuseppe, O’Hara, Jamie, Walsh, Shaun, Wilkinson, Lars   +6 more
core   +1 more source

Acquired Haemophilia Occurring in Association With Bullous Pemphigoid

JEADV Clinical Practice, EarlyView.
ABSTRACT Acquired haemophilia A (AHA) is a rare condition due to neutralizing antibodies against Factor VIII and can result in severe bleeding manifestations. The association of AHA with bullous pemphigoid (BP) is rare, most frequently observed in the elderly, and has been attributed to cross‐reactive antibodies targeting Factor VIII and BPAG2 protein.
Wen Yang Benjamin Ho, Zi Teng Chai, Haur Yueh Lee, Yen Loo Lim   +3 more
wiley   +1 more source

Assessment of Risk Factors of Septic Complications of the Puerperium [PDF]

, 2018
Postpartum purulent-septic complications (PPSC) and their problems are most urgent for modern obstetrics due to their significant frequency. Maternal sepsis is one of the leading causes of maternal mortality around the world, accounting for about one ...
Feyta, Y. (Yuliya), Pyrohova, V. (Vira)
core   +2 more sources

Distribution and predictors of haemophilia-related costs in the United Kingdom: analysis of the CHESS I and CHESS II burden of illness studies

BMC Health Services Research
Background Few studies have evaluated direct medical or societal costs of haemophilia in the United Kingdom (UK), and how patient characteristics impact future costs is uncertain.
Ione Woollacott, Amit Chhabra, Tom Burke, Jack Brownrigg, Lucy Richardson, Enrico Ferri Grazzi, Jamie O’Hara, Josie Godfrey, Michael Laffan   +8 more
doaj   +1 more source

Recombinant porcine sequence factor VIII (rpFVIII) for acquired haemophilia A: practical clinical experience of its use in seven patients

Haemophilia, 2017
A recombinant porcine factor VIII B‐domain‐deleted product (rpFVIII; OBIZUR, Baxalta Incorporated, Deerfield, IL 60015, USA) was recently approved for treatment of bleeding episodes in adults with acquired haemophilia A (AHA) in the United States.
M. Tarantino, A. Cuker, B. Hardesty, J. Roberts, M. Sholzberg   +4 more
semanticscholar   +1 more source