Results 71 to 80 of about 22,513 (247)

Patient Preferences for the Treatment of Haemophilia A and B in France

Haemophilia, EarlyView.
ABSTRACT Introduction Haemophilia impacts health and quality of life. Advances in treatments such as factor replacement therapy (FRT), bispecific monoclonal antibody (BS‐mAb), gene therapy (GT), rebalancing treatment and high sustained factor necessitate understanding patient preferences to inform therapeutic strategies. Aim This study quantified trade‐
Yesim Dargaud, Yasmine Fahfouhi, Monia Ezzalfani, Astrid Foix Colonier, Alaeddine Sidhom, Aline Gauthier, Jérémie Rudant, Meriem Kessouri, Nicolas Giraud, Benoît Guillet, Anaïs Reynaud   +10 more
wiley   +1 more source

Approach to bleeding patient

Indian Journal of Anaesthesia, 2014
Managing a bleeding patient is very challenging for the perioperative physician. Bleeding in a patient would be due to inherited or acquired disorders of haemostasis.
Ramachandran Gopinath, Y Sreekanth, Monu Yadav   +2 more
doaj   +1 more source

Real‐World Outcomes of Prophylaxis With rIX‐FP in Germany: A Prospective, Non‐Interventional Study in Haemophilia B

Haemophilia, EarlyView.
ABSTRACT Introduction Efficacy and safety of albutrepenonacog alfa (rIX‐FP) in people with haemophilia B (PwHB) has been previously demonstrated in clinical trials. However, real‐world data insights are required. Aim To describe real‐world effectiveness and tolerability of rIX‐FP in PwHB in Germany.
Johannes Oldenburg, Swee Wenning, Susanne Holzhauer, Wolfgang Miesbach, Robert Klamroth, Thomas Linhoff, Patrick Sommerer, Christian Pfrepper, Martin Olivieri, all study investigators   +9 more
wiley   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source

A comparative analysis of routine hospital admission data for sickle cell anaemia, cystic fibrosis and haemophilia in England

Scientific Reports
Recent evidence of inequalities in healthcare for sickle cell disease in the UK is lacking. We aimed to describe trends in hospital admissions for sickle cell anaemia (SCA), cystic fibrosis (CF) and haemophilia in England.
Rutendo Muzambi, Alex Bottle, Mark Layton, Daniel Dexter, Siobhán B. Carr, Carl Reynolds, John James, Cherelle Augustine, Ganesh Sathyamoorthy, Frédéric B. Piel   +9 more
doaj   +1 more source

Lack of Inhibitor Development in Previously Treated People With Haemophilia Switching Factor Products—Final Results of Athn 2: Factor Switching Study

Haemophilia, EarlyView.
Erin Cockrell, Martin Chandler, Tammuella Chrisentery‐Singleton, Stacy E. Croteau, Nabil Daoud, Michael F. Guerrera, M. Nikki Hirsh, Janna Journeycake, Roshni Kulkarni, Susan U. Lattimore, Catherine McGuinn, Margaret Ragni, Michael Recht, Ulrike M. Reiss, Robert Sidonio Jr., Cliffford M. Takemoto, Michael Tarantino, Annette von Drygalski, Ellis J. Neufeld   +18 more
wiley   +1 more source

Use of an Oral Health‐Related Quality of Life Instrument to Measure Unmet Dental Care Needs in Adults With Inherited Bleeding Disorders

Haemophilia, EarlyView.
ABSTRACT Introduction Preventive dental care is vital for individuals with bleeding disorders to reduce the need for potentially invasive procedures. Although dental care is a mandated function of U.S. federally supported hemophilia treatment centers (HTCs), access to dental care is widely variable.
Miguel A. Escobar, Megan M. Ullman, Joanna Larson, Michael M. Chan, Marisela Trujillo   +4 more
wiley   +1 more source

Physical Activity and Sedentary Behaviour in Children With Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Physical activity (PA) is vital in child development, while inactivity remains a leading contributor to global mortality. Therapeutic advances have enabled greater PA in boys with haemophilia (BwH), yet robust UK data on objectively measured PA and sedentary behaviour (SB) across severities are limited.
Melanie Bladen, Lucy Alderson, Eleanor Main, Mario Cortina‐Borja   +3 more
wiley   +1 more source

Haemophilia Management in Natural Disasters—From Field to Consensus Report

Haemophilia, EarlyView.
ABSTRACT Objective The earthquake in Türkiye had a profound impact on both haemophilia patients and healthcare services in the region. This experience highlighted the need for an effective action plan for patients with bleeding disorders in extraordinary situations.
Ahmet Muzaffer Demir, Selin Aytaç, Serap Karaman, Can Acıpayam, Muhlis Cem Ar, Bülent Antmen, Adalet Meral Güneş, Kaan Kavaklı, Hasan Kaya, Vahap Okan, Sayime Başak Koç Şenol, Ayşegül Ünüvar, Osman BülentZülfikar, Merve Altunbaş   +13 more
wiley   +1 more source

Smartphone‐Based Teledentistry to Support Clinical Triage and Risk‐Informed Dental Care in Patients With Inherited Bleeding and Haemoglobin Disorders: A Cross‐Sectional Diagnostic Agreement Study

Haemophilia, EarlyView.
ABSTRACT Introduction Patients with inherited bleeding and haemoglobin disorders face barriers to accessing timely dental care, increasing the risk of untreated oral disease and complications related to invasive procedures. Aim To evaluate the agreement between smartphone‐based asynchronous teledentistry and face‐to‐face examination for oral conditions,
Victor Cordeiro da Silva, Carolina Mendes Frusca do Monte, Leandro Tavares da Silva, Gabriela Silva Almeida, Claudia Santos Lorenzato, José Vitor Nogara Borges de Menezes, Fabian Calixto Fraiz, Cassius Carvalho Torres‐Pereira   +7 more
wiley   +1 more source