The role of bacterial secretion systems in the virulence of Gram-negative airway pathogens associated with cystic fibrosis [PDF]
, 2016 Cystic fibrosis (CF) is the most common lethal inherited disorder in Caucasians. It is caused by mutation of the CF transmembrane conductance regulator (CFTR) gene.
Depluverez, Sofie +2 more
core +2 more sources
Culture and PCR detection of Haemophilus influenzae and Haemophilus haemolyticus in Australian indigenous children with bronchiectasis [PDF]
, 2012 A PCR for protein D (hpd#3) was used to differentiate nontypeable Haemophilus influenzae (NTHI) from Haemophilus haemolyticus. While 90% of nasopharyngeal specimens and 100% of lower-airway specimens from 84 Indigenous Australian children with ...
A. B. Chang +18 more
core +2 more sources
Epidemiology of Invasive Haemophilus influenzae Disease, Europe, 2007–2014
Emerging Infectious Diseases, 2017 We describe the epidemiology of invasive Haemophilus influenzae disease during 2007–2014 in 12 European countries and assess overall H. influenzae disease trends by serotype and patient age. Mean annual notification rate was 0.6 cases/100,000 population,
R. Whittaker +5 more
semanticscholar +1 more source
Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection [PDF]
, 2015 Bioactive matrix fragments (matrikines) have been identified in a myriad of disorders, but their impact on the evolution of airway inflammation has not been demonstrated.
Snelgrove, RJ
core +1 more source
Haemophilus influenzae induces steroid-resistant inflammatory responses in COPD. [PDF]
, 2017 BACKGROUND: Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder partially resistant to glucocorticoids. A reduced histone deacetylase (HDAC) activity has been proposed to explain this resistance.
Agustí García-Navarro, Àlvar +5 more
core +1 more source
Future Microbiology, 2017 AIM To design a highly specific and sensitive multiplex real-time PCR assay for the differentiation of the pathogen Haemophilus influenzae from its nonpathogenic near-neighbor Haemophilus haemolyticus.
E. Price +7 more
semanticscholar +1 more source
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing [PDF]
, 2007 Airway infection by the Gram-positive pathogen Streptococcus pneumoniae (Sp) leads to recruitment of neutrophils but limited bacterial killing by these cells.
Clarke, Thomas B. +6 more
core +3 more sources
Polyarticular Septic Arthritis Due to Non-Typeable With Concomitant New-Onset Acute Gouty Arthritis
Journal of Investigative Medicine High Impact Case Reports, 2019 Haemophilus influenzae is serologically classified into two main categories based on the presence or absence of the polysaccharide capsule. Strains that possess polysaccharide capsules are identified as typeable Haemophilus influenzae , whereas strains ...
Brian Sanders MD +3 more
doaj +1 more source
Role of Haemophilus influenzae in Formation of Infectious Diseases in Children
Zdorovʹe Rebenka, 2013 The paper contains an analysis and synthesis of current views on the role of Haemophilus influenzae in the formation of infectious diseases in children.
G.O. Lezhenko +2 more
doaj +1 more source
The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]
, 2015 Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X +6 more
core +2 more sources