Results 41 to 50 of about 156,103 (307)

HAEMOPHILUS INFLUENZAE INFECTION IN CHILDREN DURING SPORADIC MORBIDITY: CLINICAL CASES WITH DIFFERENT (FAVORABLE OR FATAL) OUTCOMES

Вопросы современной педиатрии, 2017
Haemophilus influenzae infection in children is detected as sporadic cases and is characterized by polymorphism of clinical symptoms (rhinopharyngitis, purulent meningitis, acute epiglottitis, panniculitis, etc.), which complicates an early diagnosis and
Gennadii A. Kharchenko, Olga G. Kimirilova   +1 more
doaj   +1 more source

The role of NTHi colonization and infection in the pathogenesis of neutrophilic asthma

Respiratory Research, 2020
Asthma is a complex heterogeneous disease. The neutrophilic subtypes of asthma are described as persistent, more severe and corticosteroid-resistant, with higher hospitalization and mortality rates, which seriously affect the lives of asthmatic patients.
Jing Zhang, Zhenxing Zhu, Xu Zuo, He Pan, Yinuo Gu, Yuze Yuan, Guoqiang Wang, Shiji Wang, Ruipeng Zheng, Zhongmin Liu, Fang Wang, Jingtong Zheng   +11 more
doaj   +1 more source

Vaccines for Nontypeable Haemophilus influenzae: the Future Is Now

Clinical and Vaccine Immunology, 2015
Infections due to nontypeable Haemophilus influenzae result in enormous global morbidity in two clinical settings: otitis media in children and respiratory tract infections in adults with chronic obstructive pulmonary disease (COPD).
T. Murphy
semanticscholar   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

A biphasic epigenetic switch controls immunoevasion, virulence and niche adaptation in non-typeable Haemophilus influenzae

Nature Communications, 2015
Non-typeable Haemophilus influenzae contains an N6-adenine DNA-methyltransferase (ModA) that is subject to phase-variable expression (random ON/OFF switching).
John M. Atack, Y. Srikhanta, Kate L. Fox, J. Jurcisek, K. Brockman, Tyson A. Clark, Matthew Boitano, P. Power, F. Jen, A. McEwan, S. Grimmond, Arnold L. Smith, S. Barenkamp, J. Korlach, L. Bakaletz, M. Jennings   +15 more
semanticscholar   +1 more source

Resistance decay in individuals after antibiotic exposure in primary care: A systematic review and meta-analysis [PDF]

, 2012
Background Antibiotic resistance is an urgent global problem, but reversibility is poorly understood. We examined the development and decay of bacterial resistance in community patients after antibiotic use.
Bakhit, Mina, Hoffmann, Tammy, Scott, Anna Mae, Beller, Elaine, Rathbone, John, Del Mar, Chris   +5 more
core   +1 more source

A Hunt for the Resistance of Haemophilus influnezae to Beta-Lactams

Antibiotics
Infections due to Haemophilus influnezae require prompt treatment using beta-lactam antibiotics. We used a collection of 81 isolates obtained between 1940 and 2001 from several countries.
Mélanie Denizon, Eva Hong, Aude Terrade, Muhamed-Kheir Taha, Ala-Eddine Deghmane   +4 more
doaj   +1 more source

The Lung Immune Response to Nontypeable Haemophilus influenzae (Lung Immunity to NTHi)

Journal of Immunological Research, 2015
Haemophilus influenzae is divided into typeable or nontypeable strains based on the presence or absence of a polysaccharide capsule. The typeable strains (such as type b) are an important cause of systemic infection, whilst the nontypeable strains ...
P. King, Roleen Sharma
semanticscholar   +1 more source

Sputum Induction in Children Is Feasible and Useful in a Bustling General Hospital Practice [PDF]

, 2016
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The Jeroen Bosch Hospital funded this study.Peer reviewedPublisher ...
Bart, Ingeborg Y., de Vries, Esther, Hilbink, Mirrian, Mourits, Mariëlle, van Gent, René, van Leuken, Maarten H., Warris, Adilia, Wever, Peter C.   +7 more
core   +1 more source

The Application Value of Bronchoalveolar Lavage Fluid Metagenomic Next‐Generation Sequencing in Moderate‐to‐Severe Bronchiectasis

Journal of Clinical Laboratory Analysis, EarlyView.
This study analyzed the clinical data of 52 patients with moderate‐to‐severe bronchiectasis who were admitted to our hospital. It explored the diagnostic value of bronchoalveolar lavage fluid (BALF) metagenomic next‐generation sequencing (mNGS) in identifying infectious pathogens in patients with moderate‐to‐severe bronchiectasis, and clarified the ...
Jiachun Li, Qiuping Quan, Junshan Chen, Xiaoyun Jian, Weijie Zhan, Jingmin Wang, Rongbin Jiang   +6 more
wiley   +1 more source