Research progress on Haemophilus parasuis vaccines [PDF]
Frontiers in Veterinary ScienceHaemophilus parasuis (HPS) is the causative agent of porcine Glässer’s disease, which has become prevalent in China in recent years. It is characterized by fibrinous polyserositis, arthritis, and meningitis, but often shows mixed infection with other ...
Yu Duan +4 more
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Resistin secreted by porcine alveolar macrophages leads to endothelial cell dysfunction during Haemophilus parasuis infection [PDF]
Virulence, 2023 Haemophilus parasuis (H. parasuis) causes exudative inflammation, implying endothelial dysfunction during pathogen infection. However, so far, the molecular mechanism of endothelial dysfunction caused by H. parasuis has not been clarified.
Kexin Hua +10 more
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Enhanced Systemic and Mucosal Immune Responses to Haemophilus parasuis by Intranasal Administration of Lactic-Co-Glycolic Acid Microspheres [PDF]
VaccinesSwine Glasser’s disease, instigated by Haemophilus parasuis (H. parasuis), is a significant bacterial infection that causes substantial economic losses in pig farming operations. The role of mucosal immunity is pivotal in defending against H.
Tianyu Lei +6 more
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Proteome Analysis of Outer Membrane Vesicles From a Highly Virulent Strain of Haemophilus parasuis [PDF]
Frontiers in Veterinary Science, 2021 Haemophilus parasuis has emerged as an important bacterial pathogen in pig husbandry, as H. parasuis can coinfect pigs with a variety of pathogenic microorganisms and further cause an aggravation of the disease.
Kunli Zhang +19 more
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Design of a multi-epitope vaccine against Haemophilus parasuis based on pan-genome and immunoinformatics approaches [PDF]
Frontiers in Veterinary Science, 2022 BackgroundGlässer's disease, caused by Haemophilus parasuis (HPS), is responsible for economic losses in the pig industry worldwide. However, the existing commercial vaccines offer poor protection and there are significant barriers to the development of ...
Maonan Pang +15 more
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Modeling Co-Infection by Streptococcus suis and Haemophilus parasuis Reveals Influences on Biofilm Formation and Host Response [PDF]
Animals, 2023 Streptococcus suis (S. suis) and Haemophilus parasuis (H. parasuis) are two primary pathogens currently affecting the porcine industry. They often cause encephalitis and arthritis. They also frequently co-infect in clinical settings. In the current study,
Mengxia Gao +7 more
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Evidence for Establishing the Clinical Breakpoint of Cefquinome against Haemophilus Parasuis in China [PDF]
Pathogens, 2021 Haemophilus parasuis can cause high morbidity and mortality in swine. Cefquinome possesses excellent antibacterial activity against pathogens causing diseases of the respiratory tract.
Kun Mi +7 more
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The Role of Antibodies Against the Crude Capsular Extract in the Immune Response of Porcine Alveolar Macrophages to In Vitro Infection of Various Serovars of Glaesserella (Haemophilus) parasuis [PDF]
Frontiers in Immunology, 2021 In Glässer’s disease outbreaks, Glaesserella (Haemophilus) parasuis has to overcome the non-specific immune system in the lower respiratory tract, the alveolar macrophages.
Katarína Matiašková +8 more
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Variations in association of nasal microbiota with virulent and non-virulent strains of Glaesserella (Haemophilus) parasuis in weaning piglets [PDF]
Veterinary Research, 2020 Glaesserella (formerly Haemophilus) parasuis causes Glässer’s disease, which results in high economic loss in the swine industry. To understand the polymicrobial interactions of G.
Yasser S. Mahmmod +2 more
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Deletion of Polyamine Transport Protein PotD Exacerbates Virulence in Glaesserella (Haemophilus) parasuis in the Form of Non-biofilm-generated Bacteria in a Murine Acute Infection Model [PDF]
Virulence, 2021 Polyamines are small, polycationic molecules with a hydrocarbon backbone and multiple amino groups required for optimal cell growth. The potD gene, belonging to the ABC (ATP-binding cassette) transport system potABCD, encodes the bacterial substrate ...
Ke Dai +14 more
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