Results 41 to 50 of about 1,651 (113)

A Triplex Real‐Time PCR Assay for Simultaneous Detection of Streptococcus suis, Glaesserella parasuis, and Actinobacillus pleuropneumoniae

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine respiratory disease complex is a multifactorial disease syndrome in swine in which bacterial pathogens play important roles. Among them, Streptococcus suis (SS), Glaesserella parasuis (GPS), and Actinobacillus pleuropneumoniae (APP) are important bacterial agents associated with respiratory disease in pigs, underscoring the need for a rapid ...
Hongkun Zhuang   +6 more
wiley   +1 more source

Two Glycosyltransferase Genes of Haemophilus parasuis SC096 Implicated in Lipo-oligosaccharide Biosynthesis, Serum Resistance, Adherence and Invasion

open access: yesFrontiers in Cellular and Infection Microbiology, 2016
Haemophilus parasuis is a common opportunistic pathogen known for its ability to colonize healthy piglets and causes Glässer’s disease. The lipooligosaccharide (LOS) of H. parasuis is a potential virulence-associated factor.
Qi Zhou   +16 more
doaj   +1 more source

Characterization of Pilin A and Thioredoxin A Mutant Strains of Acinetobacter baumannii, From a Transposon Insertion Library, for Pili Production and Virulence‐Associated Properties

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
Acinetobacter baumannii transposon insertion mutant strains ΔpilA and ΔtrxA display marked reductions of surface pili. The PilA (a major pilin protein) and TrxA (thioredoxin A) deficient bacteria also show attenuation in pathogenesis including the reduction of intestinal bacterial attachment, increased phagocytic uptake and decreased mortality from ...
Jadelynn Aki   +11 more
wiley   +1 more source

Construction and Characterization of Novel Shuttle Expression Vectors for Actinobacillus succinogenes

open access: yesBiotechnology and Applied Biochemistry, Volume 72, Issue 5, Page 1265-1273, October 2025.
ABSTRACT Actinobacillus succinogenes is a ruminal microorganism of biotechnological importance due to its capacity to produce succinic acid at high yields. Despite the scientific interest in this organism, molecular vehicles for the transfer and expression of genetic material are limited compared to the existing demand.
Angélica Vallejo‐Giraldo   +7 more
wiley   +1 more source

Haemophilus parasuis α-2,3-sialyltransferase-mediated lipooligosaccharide sialylation contributes to bacterial pathogenicity

open access: yesVirulence, 2018
Bacterial lipooligosaccharide (LOS) is an important virulence-associated factor, and its sialylation largely confers its ability to mediate cell adhesion, invasion, inflammation, and immune evasion.
Huan Wang   +10 more
doaj   +1 more source

Evaluation of immunogenicity and protective efficacy of recombinant outer membrane proteins of Haemophilus parasuis serovar 5 in a murine model. [PDF]

open access: yesPLoS ONE, 2017
Glässer's disease is an economically important infectious disease of pigs caused by Haemophilus parasuis. Few vaccines are currently available that could provide effective cross-protection against various serovars of H. parasuis. In this study, five OMPs
Miao Li   +8 more
doaj   +1 more source

Development of a Ready‐To‐Use Bioluminescence Immunosensor for the One‐Step Sensitive Detection of Antibodies Against African Swine Fever Virus

open access: yesMicrobial Biotechnology, Volume 18, Issue 10, October 2025.
A ready‐to‐use bioluminescence immunosensor for rapid, one‐step detection of ASFV antibodies, offering high specificity, high sensitivity, and ease of use, with promising applications for point‐of‐care diagnostics. ABSTRACT Rapid and reliable analytical techniques play important roles in various research fields and are particularly crucial for ...
Zhonghui Zhang   +10 more
wiley   +1 more source

Phenotype‐Specific Semi‐Mechanistic Modelling of Florfenicol Time‐Kill Curves in G. Parasuis Compared to Other Respiratory Pathogens

open access: yesJournal of Veterinary Pharmacology and Therapeutics, Volume 48, Issue 4, Page 318-339, July 2025.
ABSTRACT This study examines the pharmacodynamics (PD) of florfenicol (FFN) for treating porcine respiratory diseases by comparing its effects on Glaesserella parasuis, Actinobacillus pleuropneumoniae and Pasteurella multocida. In vitro time‐kill assays and semi‐mechanistic PD modeling were used to assess bacterial growth and killing rates at varying ...
Andrew Mead   +4 more
wiley   +1 more source

Pigs Overexpressing Porcine β-Defensin 2 Display Increased Resilience to Glaesserella parasuis Infection

open access: yesAntibiotics, 2020
As the causative agent of Glässer’s disease, Glaesserella (Haemophilus) parasuis has led to serious economic losses to the swine industry worldwide. Due to the low cross-protection of vaccines and increasing antimicrobial resistance of G. parasuis, it is
Jing Huang   +11 more
doaj   +1 more source

Molecular serotyping of clinical strains of Haemophilus (Glaesserella) parasuis brings new insights regarding Glässer’s disease outbreaks in Brazil [PDF]

open access: yesPeerJ, 2019
Glässer’s disease (GD) is an important infectious disease of swine caused by Haemophilus (Glaesserella) parasuis. Vaccination with inactivated whole cell vaccines is the major approach for prevention of H.
Julia Pires Espíndola   +9 more
doaj   +2 more sources

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