Results 91 to 100 of about 40,688 (219)

Development of a Ready‐To‐Use Bioluminescence Immunosensor for the One‐Step Sensitive Detection of Antibodies Against African Swine Fever Virus

Microbial Biotechnology, Volume 18, Issue 10, October 2025.
A ready‐to‐use bioluminescence immunosensor for rapid, one‐step detection of ASFV antibodies, offering high specificity, high sensitivity, and ease of use, with promising applications for point‐of‐care diagnostics. ABSTRACT Rapid and reliable analytical techniques play important roles in various research fields and are particularly crucial for ...
Zhonghui Zhang, Xuesai Li, Qingli Niu, Jinming Wang, Yanghe Liu, Dossêh Jean Apôtre Afayibo, Wenting Chen, Songlin Yang, Hong Yin, Guiquan Guan, Jifei Yang   +10 more
wiley   +1 more source

Phenotype‐Specific Semi‐Mechanistic Modelling of Florfenicol Time‐Kill Curves in G. Parasuis Compared to Other Respiratory Pathogens

Journal of Veterinary Pharmacology and Therapeutics, Volume 48, Issue 4, Page 318-339, July 2025.
ABSTRACT This study examines the pharmacodynamics (PD) of florfenicol (FFN) for treating porcine respiratory diseases by comparing its effects on Glaesserella parasuis, Actinobacillus pleuropneumoniae and Pasteurella multocida. In vitro time‐kill assays and semi‐mechanistic PD modeling were used to assess bacterial growth and killing rates at varying ...
Andrew Mead, Abigail Hughes, Stefano Azzariti, Pierre‐Louis Toutain, Ludovic Pelligand   +4 more
wiley   +1 more source

Buscant marcadors de virulència per a la malaltia de Glässer en porcs [PDF]

, 2011
Investigadors del Centre de Recerca en Sanitat Animal (CReSA) han intentat identificar marcadors de virulència del Haemophilus parasuis, bacteri que causa infeccions respiratòries i sistèmiques en el porc amb greus conseqüències per al sector productiu ...
Aragon, Virginia
core   +1 more source

Etiology of acute respiratory disease in fattening pigs in Finland [PDF]

, 2017
Background: The objective of our study was to clinically and etiologically investigate acute outbreaks of respiratory disease in Finland. Our study also aimed to evaluate the clinical use of various methods in diagnosing respiratory infections under ...
Haimi-Hakala, Minna, Heinonen, Mari Leena, Hälli, Outi, Laine, Taina, Laurila, Tapio, Nokireki, Tiina, Nykäsenoja, Suvi, Oliviero, Claudio, Pelkola, Kirsti, Pelkonen, Sinikka, Peltoniemi, Olli, Raunio-Saarnisto, Mirja, Segales, Joaquim, Sibila, Marina   +13 more
core   +2 more sources

Pharmacokinetic–Pharmacodynamic Cutoff Values for Doxycycline in Pigs to Support the Establishment of Clinical Breakpoints for Antimicrobial Susceptibility Testing

Journal of Veterinary Pharmacology and Therapeutics, Volume 48, Issue 4, Page 300-317, July 2025.
ABSTRACT This meta‐analysis provides a population model of doxycycline (DOXY) disposition in pigs for computation of PK/PD cutoff values corresponding to differing modalities of DOXY administration orally in pigs. This analysis enables establishment of specific clinical breakpoints for the development of antimicrobial susceptibility testing of DOXY in ...
Pierre‐Louis Toutain, Alain Bousquet‐Melou, Aude A. Ferran, Béatrice B. Roques, Jérôme R. E. del Castillo, Peter Lees, Siska Croubels, Eric Bousquet, Ludovic Pelligand   +8 more
wiley   +1 more source

Haemophilus parasuis α-2,3-sialyltransferase-mediated lipooligosaccharide sialylation contributes to bacterial pathogenicity

Virulence, 2018
Bacterial lipooligosaccharide (LOS) is an important virulence-associated factor, and its sialylation largely confers its ability to mediate cell adhesion, invasion, inflammation, and immune evasion.
Huan Wang, Lu Liu, Qi Cao, Weiting Mao, Yage Zhang, Xinyi Qu, Xuwang Cai, Yujin Lv, Huanchun Chen, Xiaojuan Xu, Xiangru Wang   +10 more
doaj   +1 more source

Evaluation of immunogenicity and protective efficacy of recombinant outer membrane proteins of Haemophilus parasuis serovar 5 in a murine model. [PDF]

PLoS ONE, 2017
Glässer's disease is an economically important infectious disease of pigs caused by Haemophilus parasuis. Few vaccines are currently available that could provide effective cross-protection against various serovars of H. parasuis. In this study, five OMPs
Miao Li, Ru-Jian Cai, Shuai Song, Zhi-Yong Jiang, Yan Li, Hong-Chao Gou, Pin-Pin Chu, Chun-Ling Li, Hua-Ji Qiu   +8 more
doaj   +1 more source

Detection of Glasser's Disease in clinical samples using Polymerase chain reaction. [PDF]

, 2011
Glasser’s Disease is one of the porcine common respiratory problems in out country. Glasser’s disease is caused by Haemophilus parasuis (HP). The HP has a wide range of antibiotics sensitivity and can be treated during early infection; therefore early
Ooi, Peck Toung, Teh, See Wai
core  

Rational Design of Natural Xanthones Against Gram‐negative Bacteria

Advanced Science, Volume 12, Issue 14, April 10, 2025.
The skeletons are screened and obtained from natural xanthones to penetrate the outer membrane (OM) in Gram‐negative bacteria. The analog of α‐mangostin functionalized with amine groups crosses the OM through a self‐promoted pathway. The design and elucidation of antibacterial compounds crossing the OM facilitates the discovery of novel compounds ...
Xiaojia Liu, Meirong Song, Ying Liu, Shuyu Yang, Shang Chen, Jijun Kang, Jianzhong Shen, Kui Zhu   +7 more
wiley   +1 more source

Pathogenicity and Immunity Studies of Haemophilus Parasuis Serotypes [PDF]

Acta Veterinaria Scandinavica, 1993
After intranasal inoculation of SPF pigs with the 7 reference strains of Haemophilus parasuis only the reference strains of serotypes 1 and 5 proved to be pathogenic and were able to produce the lesions characteristic of Glässer's disease. Even though the reference strains of serotypes 2, 3, 4, 6 and 7 proved to be apathogenic, intranasal inoculation ...
openaire   +2 more sources