Results 71 to 80 of about 704,117 (312)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Prevalence and associated factors of intertrigo in aged nursing home residents: a multi-center cross-sectional prevalence study

BMC Geriatrics, 2019
Background In geriatric and long-term care settings, intertrigo seems to be common, but generalizable epidemiological estimates are lacking. Aim of this study was to measure the prevalence of intertrigo in aged nursing home residents and to identify ...
Sabrina Gabriel, Elisabeth Hahnel, Ulrike Blume-Peytavi, Jan Kottner   +3 more
doaj   +1 more source

Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth

International Journal of Cosmetic Science, 2018
Hair disorders such as hair loss (alopecia) and androgen dependent, excessive hair growth (hirsutism, hypertrichosis) may impact the social and psychological well‐being of an individual.
Alka Madaan, Ritu Verma, Anu T. Singh, M. Jaggi   +3 more
semanticscholar   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Identifying barriers and solution strategies for retailers’ adoption of virtual reality shopping– an experts’ perspective

Frontiers in Virtual Reality
Despite the potential advantages of virtual reality (VR) shopping in providing novel and immersive user experiences, retailers are reluctant to implement actual applications.
Sophia Elsholz, Danny Nguyen, Rüdiger Zarnekow   +2 more
doaj   +1 more source

Hair Analysis in Forensic Toxicology: An Updated Review with a Special Focus on Pitfalls.

Current pharmaceutical design, 2018
BACKGROUND The detection of drugs in hair analysis has progressively emerged as a consequence of the enhanced sensitivity of analytical techniques used in forensic toxicology; a greater advantage in using this matrix with respect to classical ones (i.e ...
P. Kintz
semanticscholar   +1 more source

Kerr black holes with Proca hair [PDF]

, 2016
Bekenstein proved that in Einstein's gravity minimally coupled to one (or many) real, Abelian, Proca field, stationary black holes (BHs) cannot have Proca hair.
C. Herdeiro, E. Radu, H. R'unarsson
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

A systematic review and meta-analysis of systematic and topical tranexamic acid administration in aesthetic plastic surgery

Perioperative Medicine
Introduction Tranexamic acid has been widely used in plastic surgery. However, its efficacy has yet to be fully established. This meta-analysis aimed to determine its effectiveness in aesthetic plastic surgery.
Jerzy Kolasiński, Tomasz Reysner, Małgorzata Kolenda, Szymon Kołacz, Małgorzata Domagalska   +4 more
doaj   +1 more source