Results 121 to 130 of about 5,371,069 (241)

An efficient strategy for establishing a model of sensorineural deafness in rats

Neural Regeneration Research, 2015
Ototoxic drugs can be used to produce a loss of cochlear hair cells to create animal models of deafness. However, to the best of our knowledge, there is no report on the establishment of a rat deafness model through the combined application of ...
Long Ma, Hai-jin Yi, Fen-qian Yuan, Wei-wei Guo, Shi-ming Yang   +4 more
doaj   +1 more source

Erythropoietin but not VEGF has a protective effect on auditory hair cells in the inner ear [PDF]

, 2018
It has recently been shown that the oxygen-regulated factors erythropoietin (Epo) and vascular endothelial growth factor (VEGF) confer protection on different cells, including neuronal-derived ones.
Bodmer, Daniel, Gassmann, Max, Monge Naldi, Arianne   +2 more
core  

Herbal Formula AC591 Protects Against Cisplatin‐Induced Hearing Loss by Inhibiting p53‐Mediated Ferroptosis

Smart Medicine, Volume 5, Issue 5, October 2026.
AC591 and its core active component 18β‐glycyrrhetinic acid effectively alleviate cisplatin‐induced ototoxicity by binding p53 and suppressing p53‐mediated ferroptosis, representing promising agents for preventing cisplatin‐related hearing loss. ABSTRACT Cisplatin is a widely utilized chemotherapeutic agent for the treatment of malignant cancers ...
Yunhao Wu, Yu Tao, Lin Wei, Qiuping Liu, Jiaxin Liu, Wen Jiang, Weiwei Shi, Peng Cao, Xiaolong Fu, Cheng Cheng   +9 more
wiley   +1 more source

Visual-auditory Volume Rendering of Scalar Fields

, 2019
Presented at the 25th International Conference on Auditory Display (ICAD 2019) 23-27 June 2019, Northumbria University, Newcastle upon Tyne, UK.Presented at the 25th International Conference on Auditory Display (ICAD 2019) 23-27 June 2019, Northumbria ...
Alexander Pasko, Malikova, E., Evgeniya Malikova, Valery Adzhiev, Adzhiev, V., Fryazinov, O., Oleg Fryazinov, Pasko, A.   +7 more
core   +1 more source

IGF‐1/SLC25A33 Maintains Blood‐Labyrinth Barrier Integrity by Suppressing TGF‐β/Smad2‐Mediated Pericyte Activation in Age‐Related Hearing Loss

Aging Cell, Volume 25, Issue 10, October 2026.
IGF‐1/SLC25A33–TGF‐β/Smad2 axis can regulate pericyte activation and BLB integrity, which may be a potential therapeutic target for preserving hearing in ARHL. ABSTRACT Age‐related hearing loss (ARHL) is a prevalent sensory disorder in the elderly, yet the molecular mechanisms underlying cochlear aging remain incompletely understood. While insulin‐like
Rui Xu, Jia Tang, Huan Lin, Qi Li, Yajin Feng, Xiaorong Zhang, Xiaohong Hu, Jiacai Yang, Yuhong Li, Yang Bai   +9 more
wiley   +1 more source

The in vitro plasticity of hair follicle dermal and mesenchymal stem cells [PDF]

, 2008
Stem cells from the hair follicle are an easily accessible population of cells that have a broad in vitro developmental capabilities and potential for autologous replacement of damaged adult tissue.
Emmerson, Robert
core  

1.3 channels in mouse auditory hair cells

, 2007
Sound coding at the auditory inner hair cell synapse requires graded changes in neurotransmitter release, triggered by sustained activation of presynaptic Ca(v)1.3 voltage-gated Ca2+ channels.
Meyer, Alexander C., Françoise Haeseleer, Guiying Cui, Irina Calin‐Jageman, Jakob Neef, Lee, Amy, Haeseleer, Francoise, Alexander C. Meyer, Cui, Guiying, Calin-Jageman, Irina E., Neef, Jakob, Amy Lee, Moser, Tobias, Tobias Moser   +13 more
core   +1 more source

Multi‐omics analysis of ion channels expressed by chicken embryo vestibular type I and type II hair cells

Experimental Physiology, Volume 111, Issue 10, Page 4894-4914, 1 October 2026.
Abstract Balance and gaze rely on the rapid and accurate detection and signalling of head movements by vestibular type I and type II hair cells. Signal transduction and transmission involve several types of ion channels, which are acquired progressively during hair cell differentiation and whose identity is known only in part.
Giulia Cheli, Roberta Giunta, Francesca Stella, Eleonora Guidi, Umberto Laforenza, Mariarosa Polimeni, Giancarlo Russo, Francesca Borgo, Lazarevic Dejan, Sergio Masetto   +9 more
wiley   +1 more source

The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns

Neural Plasticity, 2018
Inner ear formation requires that a series of cell fate decisions and morphogenetic events occur in a precise temporal and spatial pattern. Previous studies have shown that transcription factors, including Pax2, Sox2, and Prox1, play important roles ...
Shaofeng Liu, Yunfeng Wang, Yongtian Lu, Wen Li, Wenjing Liu, Jun Ma, Fuqin Sun, Mao Li, Zheng-Yi Chen, Kaiming Su, Wenyan Li   +10 more
doaj   +1 more source

Auditory Displays for Automated Driving — Challenges and Opportunities

, 2019
Presented at the 25th International Conference on Auditory Display (ICAD 2019) 23-27 June 2019, Northumbria University, Newcastle upon Tyne, UK.Presented at the 25th International Conference on Auditory Display (ICAD 2019) 23-27 June 2019, Northumbria ...
Lachmann, Max, Fagerlönn, Johan, Justyna Maculewicz, Maculewicz, Justyna, Max Lachmann, Pontus Larsson, Johan Fagerlönn, Larsson, Pontus   +7 more
core   +1 more source