Results 151 to 160 of about 16,285 (195)
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The efferents interconnecting auditory inner hair cells
Hearing Research, 1994The work describes the system of efferent terminals that interconnect inner hair cells through a chain of direct somatic synapses organized in repetitive patterns. The efferent boutons were discovered in the apical turns of 12-day-old (hearing) mice.
S M Slapnick, H M Sobkowicz
exaly +3 more sources
Inner hair cell synapse density influences auditory processing
2022Abstract Loss of synapses between spiral ganglion neurons and inner hair cells (IHC synaptopathy), leads to an auditory neuropathy called hidden hearing loss (HHL) characterized by normal auditory thresholds but reduced amplitude of sound-evoked auditory potentials.
Lingchao Ji +6 more
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A revised model of the inner-hair cell and auditory-nerve complex
The Journal of the Acoustical Society of America, 2002A revised computational model of the inner-hair cell (IHC) and auditory-nerve (AN) complex is presented and evaluated. Building on previous models, the algorithm is intended as a component for use in more comprehensive models of the auditory periphery. It combines smaller components that aim to be faithful to physiology in so far as is practicable and ...
Christian J, Sumner +3 more
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Simulation of the efficiency of inner hair cell secretion in the auditory pathway
2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019Sound coding involves several stages of processing along the auditory path. Specifically, the Inner Hair Cells (IHC) act as sensory receptors and transduce acoustic information -frequency, intensity and duration of the stimulus- into neuronal signals. In this work, a stochastic model was implemented to achieve a better understanding of the IHC-auditory
Jessica Soto +3 more
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Analysis of models for the synapse between the inner hair cell and the auditory nerve
The Journal of the Acoustical Society of America, 2005A general mathematical approach was proposed to study phenomenological models of the inner-hair-cell and auditory-nerve (AN) synapse complex. Two models (Meddis, J. Acoust. Soc. Am. 79(3), 702–711 (1986); Westerman and Smith, J. Acoust. Soc. Am. 83(6), 2266–2276 (1988)) were studied using this unified approach.
Xuedong, Zhang, Laurel H, Carney
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Journal of Basic and Clinical Physiology and Pharmacology, 2010
The present study was designed to assess whether, in the presence of a depression of the cochlear amplifier i.e. a sensorineural hearing loss (SNHL), the inner hair cells (IHCs) require the presence of a normal endocochlear potential for transduction. An SNHL was induced by injecting salicylic acid (which binds to the motor protein prestin in the outer
Cahtia, Adelman +2 more
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The present study was designed to assess whether, in the presence of a depression of the cochlear amplifier i.e. a sensorineural hearing loss (SNHL), the inner hair cells (IHCs) require the presence of a normal endocochlear potential for transduction. An SNHL was induced by injecting salicylic acid (which binds to the motor protein prestin in the outer
Cahtia, Adelman +2 more
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The masking level difference in chinchilla auditory cortex. Effects of inner hair cell loss
Hearing Research, 2003The purpose of the present study was to investigate responses from the unanesthetized chinchilla auditory cortex (AC) to conditions producing a masking level difference (MLD) in perceptual studies, both before and after inner hair cell (IHC) loss caused by carboplatin. Tungsten electrodes were chronically implanted in the right AC (active) and anterior
Yuqing, Guo, Robert, Burkard
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The Journal of Comparative Neurology, 1997
Ultrastructural investigation of the gamma-aminobutyric acid (GABA) component of the inner spiral bundle in adolescent mice revealed a pathway of glutamic acid decarboxylase (GAD)-positive and -negative fibers and vesiculated endings that contact inner hair cells and their afferents through a complex of axosomatic and axodendritic synapses ...
H M, Sobkowicz +3 more
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Ultrastructural investigation of the gamma-aminobutyric acid (GABA) component of the inner spiral bundle in adolescent mice revealed a pathway of glutamic acid decarboxylase (GAD)-positive and -negative fibers and vesiculated endings that contact inner hair cells and their afferents through a complex of axosomatic and axodendritic synapses ...
H M, Sobkowicz +3 more
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Hearing Research, 2020
Hair cells in the auditory organ of the vertebrate inner ear are the sensory receptors that convert acoustic stimuli into electrical signals that are conveyed along the auditory nerve to the brainstem. Hair cells are highly susceptible to ototoxic drugs, infection, and acoustic trauma, which can cause cellular degeneration.
Liangcai, Wan +3 more
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Hair cells in the auditory organ of the vertebrate inner ear are the sensory receptors that convert acoustic stimuli into electrical signals that are conveyed along the auditory nerve to the brainstem. Hair cells are highly susceptible to ototoxic drugs, infection, and acoustic trauma, which can cause cellular degeneration.
Liangcai, Wan +3 more
openaire +2 more sources