Results 161 to 170 of about 16,285 (195)
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Kainic acid selectively alters auditory dendrites connected with cochlear inner hair cells
Hearing Research, 1985Cochleas of adult guinea pigs and rats, and 6-day-old rat pups, were injected, through the round window, with 2 microliters of artificial classical Konishi perilymph containing 1 nmol kainic acid (KA). 5 min later, they were fixed, removed, and processed for electron microscopy. In all KA-treated cochleas, the injection resulted in a severe swelling of
R, Pujol +4 more
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Hearing Research, 2018
The basolateral membrane of the mammalian inner hair cell (IHC) expresses large voltage and Ca2+ gated outward K+ currents. To quantify how the voltage-dependent activation of the K+ channels affects the functionality of the auditory nerve innervating the IHC, this study adopts a model of mechanical-to-neural transduction in which the basolateral K ...
Pulkki, Ville +3 more
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The basolateral membrane of the mammalian inner hair cell (IHC) expresses large voltage and Ca2+ gated outward K+ currents. To quantify how the voltage-dependent activation of the K+ channels affects the functionality of the auditory nerve innervating the IHC, this study adopts a model of mechanical-to-neural transduction in which the basolateral K ...
Pulkki, Ville +3 more
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Journal of Comparative Neurology, 1992
AbstractThe 275 kD hair cell antigen (HCA) is a protein that is specifically associated with the apical surface of sensory hair cells in the chick inner ear. A comparative study of the vestibular and auditory organs of the inner ear, using both wholemounts and cryosections double labelled for the HCA and F‐actin, reveals that two distinct types of hair
R, Goodyear, G, Richardson
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AbstractThe 275 kD hair cell antigen (HCA) is a protein that is specifically associated with the apical surface of sensory hair cells in the chick inner ear. A comparative study of the vestibular and auditory organs of the inner ear, using both wholemounts and cryosections double labelled for the HCA and F‐actin, reveals that two distinct types of hair
R, Goodyear, G, Richardson
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Phase opposition between inner and outer hair cells and auditory sound analysis
International Journal of Audiology, 1975Recordings of single-unit responses in the auditory nerve of normal and kanamycin-treated Mongolian gerbils indicate that inner and outer hair cells of the cochlea interact in phase opposition. After kanamycin treatment, the firing rate in some fibers is increased during the basilar membrane motion toward scala vestibuli, in others, during its motion ...
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An Analog VLSI Implementation of the Inner Hair Cell and Auditory Nerve Using a Dual AGC Model
IEEE Transactions on Biomedical Circuits and Systems, 2014An analog inner hair cell and auditory nerve circuit using a dual AGC model has been implemented using 0.35 micron mixed-signal technology. A fully-differential current-mode architecture is used and the ability to correct channel mismatch is evaluated with matched layouts as well as with digital current tuning.
David S. Freedman +4 more
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Two Modes of Auditory Hair Cell Loss following Acoustic Overstimulation in the Avian Inner Ear
ORL, 2010To determine the type of cell death occurring and how the removal of damaged cells proceeds following overstimulation, we examined chick basilar papillae using an in situ DNA nick end labeling method and transmission electron microscopy. Two distinct modes of hair cell loss were identified.
T, Nakagawa +5 more
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Loss of inner hair cell ribbon synapses and auditory nerve fiber regression in Cldn14 knockout mice
Hearing Research, 2020Proper functioning of the auditory nerve is of critical importance for auditory rehabilitation by cochlear implants. Here we used the Cldn14-/- mouse to study in detail the effects of Claudin 14 loss on auditory synapses and the auditory nerve. Mutations in the tight junction protein Claudin 14 cause autosomal recessive non-syndromic hearing loss ...
Maike, Claußen +2 more
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The Journal of the Acoustical Society of America, 2023
Sensorineural hearing loss (SNHL) effects on neural coding and perception have been largely associated with outer-hair-cell (OHC) dysfunction (e.g., reduced cochlear gain, reduced compression, broadened tuning). However, both inner-hair-cell (IHC) and OHC dysfunction occur in common hearing-loss etiologies, e.g., noise-induced and age-related ...
Madhurima Patra +3 more
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Sensorineural hearing loss (SNHL) effects on neural coding and perception have been largely associated with outer-hair-cell (OHC) dysfunction (e.g., reduced cochlear gain, reduced compression, broadened tuning). However, both inner-hair-cell (IHC) and OHC dysfunction occur in common hearing-loss etiologies, e.g., noise-induced and age-related ...
Madhurima Patra +3 more
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Hearing Research, 1992
Inner hair cell (IHC) recordings were made from second turn of the guinea pig cochlea where characteristic frequencies are approximately 4000 Hz. In order to compare IHC responses with rate suppression measured in the auditory nerve, suppressors were introduced that produced little or no response in the hair cell.
M A, Cheatham, P, Dallos
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Inner hair cell (IHC) recordings were made from second turn of the guinea pig cochlea where characteristic frequencies are approximately 4000 Hz. In order to compare IHC responses with rate suppression measured in the auditory nerve, suppressors were introduced that produced little or no response in the hair cell.
M A, Cheatham, P, Dallos
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The Journal of Laryngology & Otology, 2011
AbstractThe stereocilia of the inner ear are unique cellular structures which correlate anatomically with distinct cochlear functions, including mechanoelectrical transduction, cochlear amplification, adaptation, frequency selectivity and tuning. Their function is impaired by inner ear stressors, by various types of hereditary deafness, syndromic ...
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AbstractThe stereocilia of the inner ear are unique cellular structures which correlate anatomically with distinct cochlear functions, including mechanoelectrical transduction, cochlear amplification, adaptation, frequency selectivity and tuning. Their function is impaired by inner ear stressors, by various types of hereditary deafness, syndromic ...
openaire +2 more sources