Results 1 to 10 of about 13,036 (186)

An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells [PDF]

Proceedings of the National Academy of Sciences, 2014
Significance We show that the submembrane scaffold protein Nherf1 is necessary for correct shaping of outer hair cells stereocilia bundles in the basal cochlea. The mild elevation of hearing thresholds (22–35 dB) of Nherf1 −/− mice at high frequencies was ...
Kamiya, Kazusaku, Michel, Vincent, Giraudet, Fabrice, Riederer, Brigitte, Foucher, Isabelle, Papal, Samantha, Perfettini, Isabelle, Le Gal, Sébastien, Verpy, Elisabeth, Xia, Weiliang, Seidler, Ursula, Georgescu, Maria-Magdalena, Avan, Paul, El-Amraoui, Aziz, Petit, Christine   +14 more
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Circadian-Related Serotonin/Melatonin Level Modulates Cisplatin Ototoxicity Susceptibility Depended on NOS3-NO Pathway. [PDF]

J Pineal Res
ABSTRACT Hearing impairment is attributed to factors such as age, genetic predisposition, and environmental influences, among which environmental factors are considered modifiable. Among various environmental factors, the role of poor lifestyle habits is particularly critical, yet the specific mechanisms by which they contribute to hearing damage ...
Qiu S, Cai S, Xie R, Liu C, He Y.
europepmc   +2 more sources

Electrically evoked auditory nerve responses in the cochlea with normal outer hair cells

Journal of Otology, 2009
As hybrid cochlear implant devices are increasingly used for restoring hearing in patients with residual hearing it is important to understand electrically evoked responses in cochleae having functional hair cells. To test the hypothesis that extracochlear electrical stimulation (EES) from sinusoidal current can provoke an auditory nerve response with ...
Ren, Tianying, Meng–he, Guo, Wen–xuan, He, Miller, Josef M., Nuttall, Alfred L.   +4 more
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Organic material concentration in auditory outer hair cells measured by laser interferometry [PDF]

Cytometry, 1995
AbstractOuter hair cells (OHC) of the mammalian cochlea are quasicylindrical cells of different length, which play a major role in hearing at threshold. Their particular shape allows the use of a noninvasive laser interferometric technique of isolated cells in vitro in order to measure the organic material concentration (OMC), hence the density of each
Laffon, E., Dulon, D., Aurousseau, C., Dilhaire, S., Claeys, W.   +4 more
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Sensory Transduction and Adaptation in Inner and Outer Hair Cells of the Mouse Auditory System [PDF]

Journal of Neurophysiology, 2007
Auditory function in the mammalian inner ear is optimized by collaboration of two classes of sensory cells known as inner and outer hair cells. Outer hair cells amplify and tune sound stimuli that are transduced and transmitted by inner hair cells. Although they subserve distinct functions, they share a number of common properties. Here we compare the
Eric A, Stauffer, Jeffrey R, Holt
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Viscoelastic relaxation in the membrane of the auditory outer hair cell

Biophysical Journal, 1996
The outer hair cell (OHC) in the mammalian ear has a unique membrane potential-dependent motility, which is considered to be important for frequency discrimination (tuning). The OHC motile mechanism is located at the cell membrane and is strongly influenced by its passive mechanical properties.
Ehrenstein, D., Iwasa, K.H.
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Outer Hair Cell and Auditory Nerve Function in Speech Recognition in Quiet and in Background Noise [PDF]

Frontiers in Neuroscience, 2017
The goal of this study was to describe the contribution of outer hair cells (OHCs) and the auditory nerve (AN) to speech understanding in quiet and in the presence of background noise. Fifty-three human subjects with hearing ranging from normal to moderate sensorineural hearing loss were assayed for both speech in quiet (Word Recognition) and speech in
Hoben, Richard, Easow, Gifty, Pevzner, Sofia, Parker, Mark A.   +3 more
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Effects of outer hair cell loss on the frequency selectivity of the patas monkey auditory system [PDF]

Hearing Research, 1987
This report describes a study that took advantage of the unique reactivity of the patas monkey (Erythrocebus patas) to dihydrostreptomycin-sulfate (DHSM) to investigate the effects of selective outer hair cell (OHC) lesions on psychophysical tuning curves (PTC).
Smith, D. W., Moody, David B., Stebbins, William C., Norat, M. A.   +3 more
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Auditory Brainstem Response and Outer Hair Cell Whole-cell Patch Clamp Recording in Postnatal Rats [PDF]

Journal of Visualized Experiments, 2018
The outer hair cell is one of the two types of sensory hair cells in the mammalian cochlea. They alter their cell length with the receptor potential to amplify the weak vibration of low-level sound signal. The morphology and electrophysiological property of outer hair cells (OHCs) develop in early postnatal ages.
Aoshuang, Chang, Cuixian, Li, Jianfeng, Huang, Wenlu, Pan, Yinghong, Tian, Jie, Tang   +5 more
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Mechanical properties of the lateral cortex of mammalian auditory outer hair cells

Biophysical Journal, 1996
Mammalian auditory outer hair cells generate high-frequency mechanical forces that enhance sound-induced displacements of the basilar membrane within the inner ear. It has been proposed that the resulting cell deformation is directed along the longitudinal axis of the cell by the cortical cytoskeleton.
Tolomeo, J.A., Steele, C.R., Holley, M.C.   +2 more
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