Gating of Ca2+-Activated K+ Channels Controls Fast Inhibitory Synaptic Transmission at Auditory Outer Hair Cells [PDF]
Neuron, 2000 Fast inhibitory synaptic transmission in the central nervous system is mediated by ionotropic GABA or glycine receptors. Auditory outer hair cells present a unique inhibitory synapse that uses a Ca2+-permeable excitatory acetylcholine receptor to activate a hyperpolarizing potassium current mediated by small conductance calcium-activated potassium (SK)
Oliver, Dominik +5 more
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Mutations in ap1b1 Cause Mistargeting of the Na(+)/K(+)-ATPase Pump in Sensory Hair Cells. [PDF]
, 2013 The hair cells of the inner ear are polarized epithelial cells with a specialized structure at the apical surface, the mechanosensitive hair bundle.
Kindt, Katie +14 more
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The phase response of primary auditory afferents in a songbird (Sturnus vulgaris L.) [PDF]
, 1988 The effects of stimulus frequency and intensity on phase-locking characteristics of cochlear ganglion cells were studied in the starling. All cells showed phase-locking to tone stimuli within their response area. Phase-locking at CF is found on average 9
Gleich, Otto, Narins, P. M.
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Distinct Sensory Representations of Wind and Near-Field Sound in the Drosophila Brain [PDF]
, 2010 Behavioral responses to wind are thought to play a critical role in controlling the dispersal and population genetics of wild Drosophila species, as well as their navigation in flight, but their underlying neurobiological basis is unknown.
Yorozu, Suzuko
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Static length changes of cochlear outer hair cells can tune low-frequency hearing. [PDF]
, 2018 The cochlea not only transduces sound-induced vibration into neural spikes, it also amplifies weak sound to boost its detection. Actuators of this active process are sensory outer hair cells in the organ of Corti, whereas the inner hair cells transduce ...
Ciganovic, Nikola, +18 more
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The diameters of guinea pig auditory nerve fibres: Distribution and correlation with spontaneous rate [PDF]
, 1993 In the mammalian auditory nerve physiological recordings revealed that the spontaneous discharge rate of single auditory fibres correlates with the diversity of input-output functions which may be important for intensity discrimination (e.g., Sachs and ...
Wilson, Shirley +3 more
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Differences in auditory nerve fiber responses in regard to inner and outer hair cells [PDF]
The Journal of the Acoustical Society of America, 1978 Single unit recordings were made from auditory nerve fibers in the monkey to pure tone stimuli. Extensive studies of frequency response areas suggested the existence of two types of auditory nerve fibers. One type showed a flat-bottomed response area and the other showed a conventional sharp one.
M. Nomoto, M. Maekawa
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Auditory Brainstem Response Altered in Humans With Noise Exposure Despite Normal Outer Hair Cell Function [PDF]
Ear & Hearing, 2017 Objectives: Recent animal studies demonstrated that cochlear synaptopathy, a partial loss of inner hair cell-auditory nerve fiber synapses, can occur in response to noise exposure without any permanent auditory threshold shift.
Naomi F, Bramhall +3 more
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Hair bundles of cochlear outer hair cells are shaped to minimize their fluid-dynamic resistance [PDF]
, 2017 The mammalian sense of hearing relies on two types of sensory cells: inner hair cells transmit the auditory stimulus to the brain, while outer hair cells mechanically modulate the stimulus through active feedback.
Amanuel Wolde-Kidan +2 more
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, 2012 The inner ear is our most sensitive sensory organ and can be subdivided into three functional units: organ of Corti, stria vascularis and spiral ganglion.
Diensthuber, M +3 more
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