Results 51 to 60 of about 13,036 (186)

Application of force to the cochlear wall: Effect on auditory thresholds, outer hair cell transduction, and distortion-product otoacoustic emissions [PDF]

The Journal of the Acoustical Society of America, 2006
Described are the changes in cochlear sensitivity and mechanoelectrical transduction during a novel cochlear perturbation: the application of force to the cochlear wall. While numerous methods exist to create transient shifts in the operating point of the outer hair cell (OHC) transducer, including low-frequency acoustic bias [G. Frank and M.
Greg A. O’Beirne, Robert B. Patuzzi
openaire   +1 more source

Coreceptor and Cytokine Concentrations May Not Explain Differences in Disease Progression Observed in HIV-1 Clade A and D Infected Ugandans [PDF]

, 2011
Background: The use of cellular coreceptors and modulation of cytokine concentrations by HIV to establish a productive infection is well documented. However, it is unknown whether the expression of these proteins affects the course of HIV clade A and D ...
Zampighi Lorenzo M., Schietroma, Cataldo, Wright Edward, Ernest M. Wright, Parkes-Ratanshi, Rosalind, Grosskurth, H., Woodruff Michael, Kaleebu, Pontiano, Cataldo Schietroma, Grant, P, Ernest M, Wright, E, Parkes-Ratanshi, R., Brecha Nicholas C., Van der Paal, L., Woodruff, Michael, Lieve Van der Paal, Kaleebu, P, Brecha, Nicholas C, Zampighi Guido A., Parkes-Ratanshi, R, Wright, Edward, Guido A Zampighi, Ernest M Wright, Susan Mugaba, Grosskurth Heiner, Van der Paal, Lieve, Parkes-Ratanshi Rosalind, Grosskurth, Heiner, Mugaba, Susan, Guido A. Zampighi, Kaleebu Pontiano, Mugaba, S., Wright, Ernest M, van der Paal, L, Van der Paal Lieve, Lorenzo M Zampighi, Edward Wright, Wright Ernest M., Mugaba Susan, Paul Grant, Pontiano Kaleebu, Lorenzo M. Zampighi, Kaleebu, P., Michael Woodruff, Mugaba, S, Zampighi, Lorenzo M, Grant, P., Heiner Grosskurth, Schietroma Cataldo, Rosalind Parkes-Ratanshi, Grosskurth, H, Nicholas C. Brecha, Wright, E., Grant, Paul, Zampighi, Guido A, Grant Paul, Nicholas C Brecha   +57 more
core   +1 more source

Intermediate filaments link glutamate–aspartate transporter deficiency to cochlear synaptopathy

The FEBS Journal, EarlyView.
In a healthy ear, GLAST transporters in supporting cells clear excess glutamate to protect auditory connections. When GLAST is missing, glutamate accumulates and leads to the destruction of structural scaffolding within the postsynaptic nerve endings. This internal collapse causes a loss of synapses that are essential for hearing, ultimately resulting ...
Paul Emmerich Krumpoeck, Lukas David Landegger   +1 more
wiley   +1 more source

The tympanic covering layer contributes to basilar membrane elasticity potentially influencing human frequency resolution and speech perception

Journal of Anatomy, EarlyView.
In this study we show for the first time that the human basilar membrane contains elastin produced by the so‐called tympanic covering layer. It is believed to play an important functional role in human cochlear tuning, particularly low frequencies linked to our remarkable speech and music perception.
Wei Liu, Claudia Steinacher, Alexander Glueckert, Rudolf Glueckert, Hao Li, Karin Staxäng, Anneliese Schrott‐Fischer, Hanif M. Ladak, Sumit Agrawal, Helge Rask‐Andersen   +9 more
wiley   +1 more source

Advantages of horizontal centrifugation of platelet‐rich fibrin in regenerative medicine and dentistry

Periodontology 2000, EarlyView.
Abstract The aim of this comprehensive review was to evaluate comparative studies on horizontal and fixed‐angle centrifugation methods for preparing platelet‐rich fibrin (PRF). Furthermore, additional studies utilizing horizontal PRF (H‐PRF) were systematically investigated.
Nima Farshidfar, Karol Alí Apaza Alccayhuaman, Nathan E. Estrin, Paras Ahmad, Anton Sculean, Yufeng Zhang, Richard J. Miron   +6 more
wiley   +1 more source

FM1-43 reveals membrane recycling in adult inner hair cells of the mammalian cochlea

, 2002
Neural transmission of complex sounds demands fast and sustained rates of synaptic release from the primary cochlear receptors, the inner hair cells (IHCs). The cells therefore require efficient membrane recycling.
Ashmore, JF, Griesinger, CB, Richards, CD   +2 more
core  

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Intraspecific variation of cochlear morphology in bowhead and beluga whales

The Anatomical Record, Volume 309, Issue 6, Page 1514-1529, June 2026.
Abstract The bony labyrinth of the petrosal bone, a distinctive feature of mammal skulls, is often identified in micro‐computed tomography imaging to infer species' physiological and ecological traits. When done as part of a comparative study, one individual specimen is normally considered representative of a species, and intraspecific variation is ...
John Peacock, J. G. M. Thewissen
wiley   +1 more source

Severe hearing loss and outer hair cell death in homozygous Foxo3 knockout mice after moderate noise exposure [PDF]

, 2017
Noise induced hearing loss (NIHL) is a disease that affects millions of Americans. Identifying genetic pathways that influence recovery from noise exposure is an important step forward in understanding NIHL.
Paquette, ST, Gilels, F, Beaulac, HJ, White, PM, Bullen, A   +4 more
core   +2 more sources

Perspectives on Auditory Neuropathy: Disorders of Inner Hair Cell, Auditory Nerve, and Their Synapse [PDF]

, 2008
The term auditory neuropathy (Starr, A. et al., 1996) was first used to describe a hearing disorder due to altered function of the auditory nerve in the presence of preserved functions of cochlear outer hair cells (OHCs; Starr, A. et al., 1991).
A. Starr, Michalewski, HJ, H.J. Michalewski, T. Moser, F.G. Zeng, Starr, A, Zeng, FG, Moser, T   +7 more
core   +1 more source